Rchr
J-GLOBAL ID:201801003754924788
Update date: Jan. 27, 2025 Miyamoto Tomofumi
ミヤモト トモフミ | Miyamoto Tomofumi
Affiliation and department: Job title:
Professor
Homepage URL (1): https://juntendo.ac.jp/academics/faculty/pha/ Research field (1):
Pharmaceuticals - chemistry and drug development
Research keywords (2):
糖脂質
, 天然物化学
Research theme for competitive and other funds (17): - 2019 - 2022 Functional analysis of a new glycolipid consists of mannnosyl-oxystearates
- 2014 - 2019 Identification of endogenous glycolipids that activate immune responses via lectin receptors
- 2015 - 2018 Identification of the target molecule of bis-acetylenic alcohols which inhibit the lymphangiogenesis
- 2015 - 2018 Development of a new therapy through the clarification of innate immune receptor for PAMPs in children with vasculitis
- 2013 - 2016 Analyses of the roles of CARD9-dependent innate immunity against protozoa infection
- 2012 - 2015 Nnew approch to discover the medicinal seeds using the cross-reactivity of monoclonal antibody
- 2006 - 2007 新規血管新生阻害剤ブリヨアントラチオフェンの合成と高機能化
- 2005 - 2006 アミロイド線維の凝集が関与するフォールディング病への有機化学からのアプローチ
- 2005 - 2005 新規血管新生阻害剤ブリヨアントラチオフェンの合成と作用メカニズムの解明
- 2000 - 2002 Search for the New Biological Response Modifiers Targeting on TNFα from the Marine Invertebrates
- 1997 - 1999 Research of Biologically Active Glycosphingolipids as Medical Resources from Echinoderms
- 1996 - 1996 PC12細胞の神経突起伸展作用を指標とした海洋無脊椎動物の新規分化誘導物質の探索
- 1994 - 1995 RESEARCH OF NEW MEDICINAL RESOURCES FROM MARINE INVERTEBRATES
- 1991 - 1991 Japan-German Common Researches on Pharmaceutical Natural Product Chemistry
- 1989 - 1989 有棘目動物の生産する細胞毒性活性成分の化学的研究
- 1987 - 1987 オニヒトデ棘の毒成分に関する化学的研究
- 1986 - 1987 CHEMICAL STUDY OF NEW ALLELOCHEMICS BASED ON THE MARINE NATURAL PRODUCTS
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Papers (148): -
Samvel Nazaryan, Antoine Bruguière, Nelli Hovhannisyan, Tomofumi Miyamoto, Alexandre M.M. Dias, Pierre Simon Bellaye, Bertrand Collin, Loïc Briand, Anne Claire Mitaine-Offer. Oleanolic Acid Glycosides from Scabiosa caucasica and Scabiosa ochroleuca: Structural Analysis and Cytotoxicity. Molecules. 2023. 28. 11
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Samir Hobloss, Antoine Bruguière, Anne Sophie Champy-Tixier, Tomofumi Miyamoto, Chiaki Tanaka, Simon Dessertaine, Marc Sautour, Marie Aleth Lacaille-Dubois, Anne Claire Mitaine-Offer. Oleanane-type glycosides from Weigela x Styriaca and two cultivars of W. florida: “Minor black” and “Brigela”. Phytochemistry Letters. 2022. 50. 77-84
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David Pertuit, Anne Claire Mitaine-Offer, Tomofumi Miyamoto, Chiaki Tanaka, Clément Delaude, Pierre Simon Bellaye, Bertrand Collin, Marie Aleth Lacaille-Dubois. Oleanane-type glycosides isolated from the trunk barks of the Central African tree Millettia laurentii. Fitoterapia. 2022. 159
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Akihiro Ochi, Makoto Yoritate, Tomofumi Miyamoto, Kazuteru Usui, Gorawit Yusakul, Waraporn Putalun, Hiroyuki Tanaka, Go Hirai, Satoshi Morimoto, Seiichi Sakamoto. Harringtonine Ester Derivatives with Enhanced Antiproliferative Activities against HL-60 and HeLa Cells. Journal of Natural Products. 2022. 85. 2. 345-351
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Romuald Tématio Fouedjou, Beaudelaire Kemvoufo Ponou, Rémy Bertrand Teponno, Matthias Melzig, Chiaki Tanaka, Tomofumi Miyamoto, Léon Azefack Tapondjou. Two new triterpenoid saponins: telephiifoliosides A and B from the roots of Corrigiola litoralis subsp. telephiifolia (Pourr.) Briq. Natural Product Research. 2022. 36. 19. 4949-4956
more... MISC (24): -
Anne Sophie Champy, Anne Claire Mitaine-Offer, Tomofumi Miyamoto, Chiaki Tanaka, Anna Maria Papini, Marie Aleth Lacaille-Dubois. Structural analysis of oleanane-type saponins from the roots of Wisteria frutescens. Magnetic Resonance in Chemistry. 2017. 55. 6. 595-600
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S Sakamoto, G Yusakul, R Nagamitsu, Y Tsuneura, W Putalun, T Miyamoto, H Tanaka, S Morimoto. Development of highly sensitive immunological techniques for determination of cephalotaxus alkaloids, harringtonine. Planta Medica. 2016. 81. S 01. S1-S381
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渡辺 昂, 伊藤 友治, 石橋 洋平, 合田 初美, 宮本 智文, 池田 和貴, 沖野 望, 田口 良, 伊東 信. 病原性真菌Cryptococcus neoformansのエルゴステリル-β-グルコシド分解酵素(EGCrP2)の同定とその生物機能の解明. 脂質生化学研究. 2014. 56. 187-189
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渡辺 昂, 伊藤 友治, 石橋 洋平, 合田 初美, 宮本 智文, 池田 和貴, 沖野 望, 田口 良, 伊東 信. 病原体が広げる膜生化学、膜生化学が切り込む感染症 クリプトコッカス症原因菌の糖脂質代謝経路の解明から浮上した抗真菌剤の新しいターゲット. 日本生化学会大会プログラム・講演要旨集. 2013. 86回. 1S02a-1
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渡辺 昂, 伊藤 友治, 石橋 洋平, 合田 初美, 宮本 智文, 池田 和貴, 沖野 望, 田口 良, 伊東 信. 病原性真菌Cryptococcus neoformansのEGCrP2の基質特異性の検討. 日本生化学会大会プログラム・講演要旨集. 2012. 85回. 2P-055
more... Professional career (1): - Ph.D (Pharmaceutical Sciences) (Kyushu University)
Work history (6): Awards (1): - 2007/09 - 日本生薬学会 2007年度日本生薬学会学術貢献賞 分子標的スクリーニングによる新しい天然医薬シーズの探索
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