Hironari Kamikubo

カミクボヒロナリ | Hironari Kamikubo

Affiliation and department：
Homepage URL (1)： http://mswebs.naist.jp/LABs/kamikubo/index.html

Research field (4)： Biophysics , Bio-, chemical, and soft-matter physics , Basic physical chemistry , Structural biochemistry

Research keywords (9)： Photoreceptor , Structural Biology , Protein Design , Protein Folding , Neutron Crystallography , X-ray scattering , Structual Proteins , Complex Molecular Systems , Proteins

Research theme for competitive and other funds (25)：

2022 - 2027 Simplifying complexity and diversity of circadian clocks
2023 - 2026 Time-Dependent Modulation of KaiC-KaiA/KaiB Binding Modes in the Autonomous Oscillation Process of the Kai System
2017 - 2022 An Integrated Multi-scale Approach for Studying Cyanobacterial Circadian Clock System
2015 - 2019 International Activity Support for Dynamical ordering of biomolecular systems for creation of integrated functions
2013 - 2018 Exploring regulatory association and dissociation processes of biological molecules constituting a functional module

2013 - 2018 Management for Dynamical ordering of biomolecular systems for creation of integrated functions

2013 - 2016 Femtosecond Structural Study for Visualization of the Primary Dynamics of Photoreceptor Proteins

2012 - 2016 Strucuter and Photochemical Reactions of Photoactive Yellow Proteins: Generality and diversity

2013 - 2015 Study of bio-sensors based on ionic-liquid top-gated graphene field-effect transistors

2011 - 2014 Extraction and application of structural and functional elements of proteins.

2011 - 2013 Molecular mechanism for divergent interactions in PAS domain proteins

2008 - 2012 Development of model systems for intrinsically disordered protein and understanding of the role of fluctuation on molecular recognition and folding

2010 - 2011 蛋白質中に存在する低障壁水素結合の特性解析

2009 - 2010 Analysis of hierarchical structure of proteins network

2008 - 2010 Elucidation of protein dynamics as the control of protein function

2008 - 2008 蛋白質内水素結合ネットワークの直接観測

2006 - 2007 クラスリン小胞輸送に関与する蛋白質群の蛋白質-蛋白質相互作用の構造学的解析

2005 - 2006 Weak interactions that regulate the structure and function of the proteins

2004 - 2005 二成分情報伝達系におけるセンサー型ヒスチジンキナーゼの分子スイッチ機構の解明

2004 - 2005 Studies on the principle of protein architecture by the simplification of amino acid sequence

2002 - 2003 蛋白質表面に分布する水和水クラスターのダイナミクス

2001 - 2003 Structure, Properties and Function of Photoactive Yellow Protein

1999 - 2003 フォトンファクトリーにおける生物マシーナリー研究のためのより効率的な放射光利用法

1999 - 2000 マイクロ秒領域での蛋白質の動的構造変化の解明

1997 - 1999 Experimental and Theoretical Studies on Protein Dynamics and Changes in Dynamics upon Folding

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Papers (260)：

Miki Kariya, Kenichiro Omoto, Kaoru Nomura, Kento Yonezawa, Hironari Kamikubo, Toshio Nishino, Tomomi Inoie, Gwénaël Rapenne, Kazuma Yasuhara. Lipid cubic phase with an organic-inorganic hybrid structure formed by organoalkoxysilane lipid. Chemical Communications. 2024
Ibuki Nakamura, Hiroshi Amesaka, Mizuho Hara, Kento Yonezawa, Keisuke Okamoto, Hironari Kamikubo, Shun-ichi Tanaka, Takashi Matsuo. Conformation state-specific monobodies regulate the functions of flexible proteins through conformation trapping. Protein Science. 2023
Suhyang Kim, Yusuke Nakasone, Akira Takakado, Yoichi Yamazaki, Hironari Kamikubo, Masahide Terazima. A unique photochromic UV-A sensor protein, Rc-PYP, interacting with the PYP-binding protein. Physical Chemistry Chemical Physics. 2021. 23. 33. 17813-17825
Hikaru Kuramochi, Satoshi Takeuchi, Hironari Kamikubo, Mikio Kataoka, Tahei Tahara. Skeletal Structure of the Chromophore of Photoactive Yellow Protein in the Excited State Investigated by Ultraviolet Femtosecond Stimulated Raman Spectroscopy. The Journal of Physical Chemistry B. 2021. 125(23). 23. 6154-6161
Yasumichi Takase, Yoichi Yamazaki, Yugo Hayashi, Sachiko Toma-Fukai, Hironari Kamikubo. Structure elements can be predicted using the contact Volume among protein residues. Biophysics and Physicobiology. 2021. v18.006. 50-59

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MISC (40)：

高瀬安迪, 山崎洋一, 林有吾, 米澤健人, 米澤健人, 藤間祥子, 上久保裕生, 上久保裕生. TIMバレルファミリーにおける構造エレメントの分子進化学的考察. 日本蛋白質科学会年会プログラム・要旨集. 2021. 21st
青山理紗子, 山崎洋一, 米澤健人, 向山厚, 林有吾, 藤間祥子, 清水伸隆, 秋山修志, 上久保裕生, 上久保裕生. Titration analysis of KaiA for KaiC using continuous titration small angle X-ray scattering. 日本化学会春季年会講演予稿集(CD-ROM). 2020. 100th
AOYAMA Risako, YAMAZAKI Yoichi, YONEZAWA Kento, MUKAIYAMA Atsushi, HAYASHI Yugo, TOMA-FUKAI Sachiko, SHIMIZU Nobutaka, AKIYAMA Shuji, KAMIKUBO Hironari, KAMIKUBO Hironari. Titration analysis of KaiA for KaiC using continuous titration small angle X-ray scattering. 生物物理(Web). 2019. 59. Supplement 1-2
秋山芳展, 秋山光市郎, 岩間(舛井)千草, 大門康志, 檜作洋平, 水野慎也, 宮崎亮次, 森博幸, 禾晃和, 塩田拓也, et al. 大腸菌表層ストレス応答:インプットとアウトプットに働くプロテアーゼの機能. Institute for Fermentation, Osaka. Research Communications. 2019. 33
Matsumoto Takahiro, Yamaguchi Mariko, Shiba Rumi, Kamikubo Hironari, Yamazaki Yoichi, Kataoka Mikio. Main-chain dynamics of staphylococcal nuclease by tryptophan triplet state lifetime. Meeting abstracts of the Physical Society of Japan. 2013. 68. 2. 339-339

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Patents (5)：

タンパク質微小体及びその製造方法
ナノファイバーの製造方法
ポリペプチド(PAIR配列そのもの)
ポリペプチド(PAIR配列算出のアルゴリズム)
タンパク質構造体の製造方法

Lectures and oral presentations (8)：

Artificial reconstitution of the multi-hierarchical structure in spider silk from fibroin proteins
(2019)
マルチドメイン蛋白質をプラットフォームとした蛋白質複合系の相互作用・構造解析
(第41回日本分子生物学会年会 2018)
Structural analysis of multiple-component systems using continuous titration SAXS
(2018)
光による蛋白質分子複合系の自由エネルギーランドスケープの変調
(日本化学会第98回春季年会 2018)
連続滴定溶液散乱測定による蛋白質分子複合系の多成分平衡状態の解析
(第40回溶液化学シンポジウム 2017)

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Education (2)：

1993 - 1998 Osaka University Graduate School of Science Department of Physics
1989 - 1993 Osaka University School of Science Department of Physics

Professional career (1)：

博士(理学) (大阪大学)

Work history (4)：

2017/03 - 現在 Nara Institute of Science and Technology Division of Materials and Science Professor
2007/04 - 2017/03 Nara Institute of Science and Technology Division of Materials and Science Associate Professor
2001/04 - 2007/03 Nara Institute of Science and Technology Division of Materials and Science Assistant Professor
1998/04 - 2001/03 High Energy Accelerator Research Organization Institute of Materials Structure Science Assistant Professor

Association Membership(s) (5)：

THE JAPANESE SOCIETY FOR NEUTRON SCIENCE , THE JAPANESE SOCIETY FOR SYNCHROTRON RADIATION RESEARCH , PROTEIN SCIENCE SOCIETY OF JAPAN , THE PHYSICAL SOCIETY OF JAPAN , THE BIOPHYSICAL SOCIETY OF JAPAN

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