Ito Ayaka

Affiliation and department：
Job title： Assistant Professor

Research field (3)： Metabolism and endocrinology , Pathobiochemistry , Nutrition and health science

Research keywords (4)： Autoimmune disease , Immunometabolism , Immunology , Lipid metabolism

Research theme for competitive and other funds (11)：

2022 - 2025 免疫細胞内脂肪酸代謝の抗体産生における意義の解明
2021 - 2023 グリア内脂質代謝を介した脳-身体連関と末梢自己免疫応答制御の解明
2019 - 2023 慢性炎症性疾患の免疫細胞における脂質リプログラミングの意義の解明
2019 - 2022 Quality and amount of lipid in autoimmune diseases
2017 - 2018 自己免疫疾患発症における細胞内コレステロール代謝の病態生理的意義

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Papers (23)：

Michiko Itoh, Atsushi Tamura, Sayaka Kanai, Miyako Tanaka, Yohei Kanamori, Ibuki Shirakawa, Ayaka Ito, Yasuyoshi Oka, Isao Hidaka, Taro Takami, et al. Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH. The Journal of experimental medicine. 2023. 220. 11
Takayuki Inoue, Bin Fu, Miwako Nishio, Miyako Tanaka, Hisashi Kato, Masashi Tanaka, Michiko Itoh, Hajime Yamakage, Kozue Ochi, Ayaka Ito, et al. Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis. Nutrients. 2023. 15. 2. 350
Naoki Yoshioka, Miyako Tanaka, Kozue Ochi, Akiko Watanabe, Kenji Ono, Makoto Sawada, Tomoo Ogi, Michiko Itoh, Ayaka Ito, Yukihiro Shiraki, et al. The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021. 140. 111738-111738
Azusa Kobayashi, Ayaka Ito, Ibuki Shirakawa, Atsushi Tamura, Susumu Tomono, Hideo Shindou, Per Niklas Hedde, Miyako Tanaka, Naotake Tsuboi, Takuji Ishimoto, et al. Dietary Supplementation With Eicosapentaenoic Acid Inhibits Plasma Cell Differentiation and Attenuates Lupus Autoimmunity. Frontiers in Immunology. 2021. 12
Kento Kurita, Hiroya Ohta, Ibuki Shirakawa, Miyako Tanaka, Yasuyuki Kitaura, Yorihiro Iwasaki, Takashi Matsuzaka, Hitoshi Shimano, Seiichiro Aoe, Hiroshi Arima, et al. Macrophages rely on extracellular serine to suppress aberrant cytokine production. Scientific reports. 2021. 11. 1. 11137-11137

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MISC (13)：

伊藤パディジャ綾香, 菅波孝祥. 細胞内脂質代謝による免疫代謝と慢性炎症性疾患. 実験医学増刊「栄養・代謝物シグナルと食品機能」. 2022. 40. 7. 219-225
伊藤綾香, 菅波孝祥. 動脈硬化と自然炎症. 炎症と免疫. 2019. 27. 4. 70-74
伊藤綾香, 菅波孝祥. 慢性炎症性疾患における脂質代謝異常の意義. 2019. 48. 6. 447-451
伊藤綾香, 菅波孝祥. 細胞内脂質代謝とイムノメタボリズム. The Lipid. 2019. 30. 2. 15-21
Ito A, Suganami T. Lipoquality in chronic inflammatory diseases. Journal of Clinical and Experimental Medicine. 2018. 264. 11. 944-948

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Lectures and oral presentations (5)：

Cholesterol accumulation in CD11c+ immune cells is a causal and targetable factor in autoimmune disease
(The 47th Annual Meeting of the Japanese Society for Immunology 2018)
Molecular crosstalk between cholesterol metabolism and immune responses
(The 4th IMCR Symposium on endocrine and metabolism 2018)
Molecular crosstalk between lipid metabolism and immune responses
(The 36th JES Summer Seminar Endocrinology & Metabolism 2018)
Cholesterol accumulation in CD11c+ immune cells is a causal and targetable factor in autoimmune disease
(Cell Symposia 2018)
Cellular cholesterol metabolism in autoimmune disease
(The 91st Annual Meeting of the Japan Endocrine Society 2018)

Education (3)：

2004 - 2008 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
2002 - 2004 Kyoto University Graduate School of Agriculture
1998 - 2002 Nara Women's University Faculty of Human Life and Environment

Professional career (1)：

Ph.D. (Medical Science) (Tokyo Medical and Dental University)

Work history (7)：

2021/11 - 現在名古屋大学高等研究院若手新分野創成研究ユニット心身相関病態研究ユニット講師(兼務)
2021/11 - 現在名古屋大学環境医学研究所分子代謝医学分野講師
2020/04 - 2021/10 名古屋大学高等研究院若手新分野創成研究ユニット心身相関病態研究ユニット助教(兼務)
2018/04 - 2021/10 Nagoya University Research Institute of Environmental Medicine Assistant Professor
2017/06 - 2018/03 Nagoya University Research Institute of Environmental Medicine Adjunct Assistant Professor

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Awards (3)：

2018/04 - Japan Society of Molecular Medicine Young Investigator Award
2014/04 - Japan Endocrine Society Young Investigator Award
2007/10 - Japan Society for the Study of Obesity Young Investigator Award

Association Membership(s) (4)：

JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE , THE JAPANESE SOCIETY FOR IMMUNOLOGY , JAPAN SOCIETY FOR THE STUDY OF OBESITY , The Japan Endocrine Society

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