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J-GLOBAL ID：201801004282493997 Update date: Apr. 02, 2025

AKINORI KANAI

カナイアキノリ | AKINORI KANAI

Affiliation and department：
Job title： Project Associate Professor

Research field (1)： Molecular biology

Research theme for competitive and other funds (15)：

2022 - 2027 Development of novel therapies for ENL-mutated Wilms tumor
2022 - 2027 幹細胞の可視化によるがん化プロセス解析マウスモデルを用いた放射線発がん機構の解明
2023 - 2026 Development of Combination Radiation Therapy Drugs to Improve Cancer Control Rates by Regulating DNA Damage Response Molecules
2022 - 2025 Mechanisms of AF10-rearranged leukemia
2021 - 2024 Samd9/9L症候群とIFNシグナルから迫るMDS発症の分子メカニズム

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Papers (85)：

Yuma Takano, Jun Suzuki, Kotaro Nomura, Gento Fujii, Junko Zenkoh, Hitomi Kawai, Yuta Kuze, Yukie Kashima, Satoi Nagasawa, Yuka Nakamura, et al. Spatially resolved gene expression profiling of tumor microenvironment reveals key steps of lung adenocarcinoma development. Nature communications. 2024. 15. 1. 10637-10637
Yuichiro Nakata, Shion Nagasawa, Yasuyuki Sera, Norimasa Yamasaki, Akinori Kanai, Kohei Kobatake, Takeshi Ueda, Miho Koizumi, Ichiro Manabe, Osamu Kaminuma, et al. PTIP epigenetically regulates DNA damage-induced cell cycle arrest by upregulating PRDM1. Scientific reports. 2024. 14. 1. 17987-17987
Dustin C Becht, Akinori Kanai, Soumi Biswas, Mohamed Halawa, Lei Zeng, Khan L Cox, Michael G Poirier, Ming-Ming Zhou, Xiaobing Shi, Akihiko Yokoyama, et al. The winged helix domain of MORF binds CpG islands and the TAZ2 domain of p300. iScience. 2024. 27. 4. 109367-109367
Nitika Gaurav, Akinori Kanai, Catherine Lachance, Khan L Cox, Jiuyang Liu, Adrian T Grzybowski, Nehmé Saksouk, Brianna J Klein, Yosuke Komata, Shuhei Asada, et al. Guiding the HBO1 complex function through the JADE subunit. Nature structural & molecular biology. 2024
Akira Nishimura, Kazuaki Yokoyama, Takuya Naruto, Chika Yamagishi, Toshihiko Imamura, Hiroto Nakazono, Shunsuke Kimura, Mieko Ito, Maiko Sagisaka, Yukie Tanaka, et al. Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type. Science advances. 2023. 9. 50. eadj4407

MISC (53)：

神力悟, 平山真弓, 金井昭教, 長町安希子, 稲葉俊哉, 松井啓隆. DDX41の機能抑制による翻訳変化とR-loopの蓄積. 日本癌学会総会記事. 2021. 80回. [P14-2]
長町安希子, 松井啓隆, 金井昭教, 神力悟, 稲葉俊哉. SAMD9/9L症候群の7q-/MDS多発におけるIFNγシグナルの関与. 日本癌学会総会記事. 2021. 80回. [J14-2]
長町安希子, 松井啓隆, 金井昭教, 神力悟, 稲葉俊哉. Involvement of IFNγ in the development of 7q-/MDS in patients with SAMD9/9L syndromes(和訳中). 日本血液学会学術集会. 2021. 83回. OS3-5
長町安希子, 松井啓隆, 金井昭教, 神力悟, 稲葉俊哉. SAMD9/9L症候群の7q-/MDS多発におけるIFNγシグナルの関与. 日本癌学会総会記事. 2021. 80回. [J14-2]
神力悟, 平山真弓, 金井昭教, 長町安希子, 稲葉俊哉, 松井啓隆. DDX41の機能抑制による翻訳変化とR-loopの蓄積. 日本癌学会総会記事. 2021. 80回. [P14-2]

Professional career (1)：

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