Yuji Tokunaga

トクナガユウジ | Yuji Tokunaga

Affiliation and department：

Research field (1)： Structural biochemistry

Research keywords (1)： Nuclear magnetic resonance, proteins, nucleic acids

Research theme for competitive and other funds (7)：

2020 - 2023 遺伝情報の再定義:DNAと水の協同運動を反映した反復配列の概念導入
2020 - 2023 高活性化合物を創生し創薬標的の枯渇を解消する動的構造創薬技術の確立
2020 - 2022 中分子の膜透過を評価し膜透過活性を付与する創薬基盤技術の構築
2019 - 2022 膜タンパク質の膜貫通領域におけるシステイン残基を介したレドックス感知機構
2018 - 2020 NMR method to obtain structural fingerprints of an intact monoclonal antibody acquired under formulated storage conditions

Show all

Papers (17)：

Yuji Tokunaga, Masahito Tanaka, Hitoshi Iida, Moto Kinoshita, Yuya Tojima, Koh Takeuchi, Masahiko Imashimizu. Nonthermal excitation effects mediated by subterahertz radiation on hydrogen exchange in ubiquitin. Biophysical journal. 2021
Koh Takeuchi, Imai Misaki, Yuji Tokunaga, Miwa Fujisaki, Hajime Kamoshida, Takeshi Takizawa, Hiroyuki Hanzawa, Ichio Shimada. Conformational Plasticity of Cyclic Ras-Inhibitor Peptides Defines Cell Permeabilization Activity. Angewandte Chemie (International ed. in English). 2021. 60. 12. 6567-6572
Yuji Tokunaga, Koh Takeuchi. Role of NMR in High Ordered Structure Characterization of Monoclonal Antibodies. International journal of molecular sciences. 2020. 22. 1
Masahiko Imashimizu, Yuji Tokunaga, Ariel Afek, Hiroki Takahashi, Nobuo Shimamoto, David B Lukatsky. Control of Transcription Initiation by Biased Thermal Fluctuations on Repetitive Genomic Sequences. Biomolecules. 2020. 10. 9
Yumiko Mizukoshi, Koh Takeuchi, Yuji Tokunaga, Hitomi Matsuo, Misaki Imai, Miwa Fujisaki, Hajime Kamoshida, Takeshi Takizawa, Hiroyuki Hanzawa, Ichio Shimada. Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium. Science advances. 2020. 6. 40

ｍore...

MISC (1)：

Books (1)：

Education (4)：

2009 - 2012 The University of Tokyo Graduate School of Pharmaceutical Sciences Doctor course
2007 - 2009 The University of Tokyo Graduate School of Pharmaceutical Sciences
2005 - 2007 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
2003 - 2005 The University of Tokyo College of Arts and Sciences

Work history (6)：

2021/04 - 現在 National Institute of Advanced Industrial Science and Technology Cellular and Molecular Biotechnology Research Institute Research scientist
2020/04 - 2021/03 National Institute of Advanced Industrial Science and Technology Cellular and Molecular Biotechnology Research Institute Research scientist on tenure truck
2016/04 - 2020/03 National Institute of Advanced Industrial Science and Technology Molecular Profiling Research Center for Drug Discovery Research scientist on tenure truck
2013/08 - 2016/03 Japan Biological Informatics Consortium Department of Research and Development Postdoctoral fellow
2013/04 - 2013/07 National Institute of Advanced Industrial Science and Technology Molecular Profiling Research Center for Drug Discovery Postdoctoral fellow

Show all

Awards (2)：

Association Membership(s) (2)：

The Nuclear Magnetic Resonance Society of Japan , The Biophysical Society of Japan

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page