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J-GLOBAL ID:201801005635411244   Update date: Apr. 08, 2025

Takahito Miyake

ミヤケ タカヒト | Takahito Miyake
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Affiliation and department:
Job title: Associate Professor
Research field  (4): Metabolism and endocrinology ,  Neuroscience - general ,  Cell biology ,  Molecular biology
Research keywords  (5): 温度生物学 ,  Molecular Biology ,  Biochemistry ,  Neuroscience ,  Circadian clock
Research theme for competitive and other funds  (6):
  • 2024 - 2028 uORFー非翻訳領域の翻訳ーが支配する生命機能の解明
  • 2023 - 2026 神経病態薬理学基盤拡張にむけたプレシナプトロジーの創成
  • 2022 - 2024 Mechanism of uORF-mediated biological clock phase control by physiological temperature changes
  • 2022 - 2024 神経間シナプス接続捕捉システムが明かす「時刻」の出力回路基盤
  • 2019 - 2022 Molecular mechanisms underlying circadian pruritic behavior for chronopharmacology
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Papers (35):
  • Tomohiro Otani, Takahito Miyake, Takumi Ota, Daisuke Yarimizu, Yuuki Nakagawa, Iori Murai, Hitoshi Okamura, Emi Hasegawa, Masao Doi. Identification of angiotensin II-responsive circadian clock gene expression in adrenal zona glomerulosa cells and human adrenocortical H295R cells. Frontiers in Endocrinology. 2025. 16. 1525844
  • Khanh Tien Nguyen Pham, Takahito Miyake, Tomo Suzuki, Shigeru Kinoshita, Yuki Hamada, Hikari Uehara, Mamiko Machida, Takeshi Nakajima, Emi Hasegawa, Masao Doi. Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity. iScience. 2025. 28. 2. 111808
  • Takahito Miyake, Kaho Tanaka, Yutsuki Inoue, Yuji Nagai, Reo Nishimura, Takehito Seta, Shumpei Nakagawa, Ken-Ichi Inoue, Emi Hasegawa, Takafumi Minamimoto, et al. Size-reduced DREADD derivatives for AAV-assisted multimodal chemogenetic control of neuronal activity and behavior. Cell reports methods. 2024. 4. 10. 100881-100881
  • Takahito Miyake, Yuichi Inoue, Yota Maekawa, Masao Doi. Circadian Clock and Body Temperature. Advances in Experimental Medicine and Biology. 2024. 1461. 177-188
  • Kotaro Tomuro, Mari Mito, Hirotaka Toh, Naohiro Kawamoto, Takahito Miyake, Siu Yu A. Chow, Masao Doi, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki. Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts. Nature Communications. 2024. 15. 1. 7061
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MISC (17):
Lectures and oral presentations  (37):
  • 温度と活性酸素種を介した生命の環境適応機構の解明
    (日本薬学会第145年会 2025)
  • ポスト転写制御がもたらす生命機能の解明に向けて
    (第4回日本神経化学会 若手KYOUEN 2025)
  • 概日体温リズムによる転写によらない生物時計調律機構の解明
    (第31回 日本時間生物学会学術大会 2024)
  • Post-transcriptional制御による体内時計時刻調律機構
    (第97回日本生化学会大会 2024)
  • The minimal upstream open reading frame of Per2 has a role in enhancing the integrity of the physiological circadian response
    (2024)
more...
Education (3):
  • 2014 - 2017 Kyoto University Graduate School of Pharmaceutical Sciences Department of Molecular Pharmacology
  • 2012 - 2014 Kyoto University Graduate School of Pharmaceutical Sciences Department of Molecular Pharmacology
  • 2008 - 2012 Kyoto University Faculty of Pharmaceutical Scieonces Division of Pharmaceutical Sciences
Professional career (1):
  • 博士(薬科学) (京都大学大学院薬学研究科)
Work history (7):
  • 2025/04 - 現在 Kwansei Gakuin University School of Biological and Environmental Sciences Department of Biomedical Sciences Associate Professor
  • 2018/10 - 2025/03 Graduate School of Pharmaceutical Sciences, Kyoto University Department of Systems Biology Assistant Professor
  • 2018/05 - 2018/11 JSPS Overseas Research Fellowships
  • 2017/05 - 2018/11 University of California, San Francisco Department of Physiology Postdoctoral scholar
  • 2017/04 - 2017/04 Graduate School of Pharmaceutical Sciences, Kyoto University Department of Molecular Pharmacology Researcher
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Awards (11):
  • 2024/11 - 日本薬学会 奨励賞 温度と活性酸素種を介した生命の環境適応機構の解明
  • 2024/08 - 日本時間生物学会 奨励賞 概日体温リズムによる転写によらない生物時計調律機構の解明
  • 2024/02 - 先端モデル動物プラットフォーム 優秀ポスター賞
  • 2022/03 - 日本薬学会 長井記念若手薬学研究者賞
  • 2017/03 - 日本薬理学会 ナノシンポジウム優秀発表賞
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Association Membership(s) (5):
THE JAPAN NEUROSCIENCE SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本時間生物学会 ,  日本分子生物学会 ,  日本内分泌学会
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