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J-GLOBAL ID:201801005677937742   Update date: Jan. 21, 2025

Sakurai Hajime

サクライ ハジメ | Sakurai Hajime
Clips
Affiliation and department:
Job title: Assistant Professor
Research field  (1): Cell biology
Research keywords  (1): 細胞生物学
Research theme for competitive and other funds  (8):
  • 2024 - 2027 ゴルジ体ストレスに呼応する、ゴルジ体分解を介した恒常性維持機構の解析
  • 2024 - 2025 新規オートファジー機構GOMEDから拓く創薬基盤構築
  • 2024 - 2025 ゴルジ体恒常性維持機構から迫る潰瘍性大腸炎の創薬基盤構築
  • 2024 - 2025 2型糖尿病における膵臓β細胞『疲弊』のメカニズムの解明
  • 2021 - 2023 Study of alternative function of Golgi apparatus
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Papers (14):
  • Kanae Sasaki, Marika Toide, Takuya Adachi, Fumi Morishita, Yuto Watanabe, Hajime Tajima Sakurai, Sadao Wakabayashi, Satoshi Kusumi, Toshiyuki Yamaji, Kaori Sakurai, et al. Dysregulation of PI4P in the trans Golgi regions activates the mammalian Golgi stress response. The Journal of biological chemistry. 2024. 108075-108075
  • Hajime Tajima Sakurai, Satoko Arakawa, Hirofumi Yamaguchi, Satoru Torii, Shinya Honda, Shigeomi Shimizu. An Overview of Golgi Membrane-Associated Degradation (GOMED) and Its Detection Methods. Cells. 2023. 12. 24. 2817-2817
  • Satoru Torii, Satoko Arakawa, Shigeto Sato, Kei-Ichi Ishikawa, Daisuke Taniguchi, Hajime Tajima Sakurai, Shinya Honda, Yuuichi Hiraoka, Masaya Ono, Wado Akamatsu, et al. Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2. EMBO molecular medicine. 2023. e17451
  • Hajime Tajima Sakurai, Hidefumi Iwashita, Satoko Arakawa, Alifu Yikelamu, Mizuki Kusaba, Satoshi Kofuji, Hiroshi Nishina, Munetaka Ishiyama, Yuichiro Ueno, Shigeomi Shimizu. Development of small fluorescent probes for the analysis of autophagy kinetics. iScience. 2023. 26. 7. 107218-107218
  • Kanae Sasaki, Miyu Sakamoto, Iona Miyake, Reishi Tanaka, Ryuya Tanaka, Azusa Tanaka, Misaki Terami, Ryota Komori, Mai Taniguchi, Sadao Wakabayashi, et al. Expression of transcription factors KLF2 and KLF4 is induced by the mammalian Golgi stress response. 2023
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MISC (2):
  • 医学別冊『疾患研究につながるオルガネラ実験必携プロトコール』. 第3章-4 GOMEDの解析方法. 2024
  • Detection of closed autophagic compartment by photobleaching-technique. 2023. 34. 9. 6-9
Lectures and oral presentations  (30):
  • ゴルジ体ストレス応答とGOMEDのクロストーク機構の解析
    (第46回日本分子生物学会年会 2023)
  • ゴルジ体関連分解GOMEDを可視化する蛍光プローブの開発
    (第17回日本臨床ストレス応答学会大会 2023)
  • ゴルジ体ストレス応答によるGOMED因子と糖鎖修飾酵素の発現制御機構
    (第96回日本生化学会大会 2023)
  • 新規開発低分子化合物による生体内オートファジーの可視化
    (第44回日本分子生物学会年会)
  • 新規開発低分子化合物による生体内オートファジーの可視化
    (2019年度・2020年度難治疾患研究所研究発表会 2021)
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Education (4):
  • 2009 - 2014 東京大学大学院 理学系研究科 生物科学専攻
  • 2007 - 2009 東京大学大学院 理学系研究科 生物科学専攻
  • 2005 - 2007 The University of Tokyo
  • 2003 - 2005 東京大学 理科II類
Professional career (1):
  • Ph.D. (Science) (The University of Tokyo)
Work history (7):
  • 2023/04 - 現在 University of Hyogo
  • 2022/04 - 2023/03 Tokyo Medical and Dental University Medical Research Institute
  • 2021/06 - 2022/03 Tokyo Medical and Dental University Medical Research Institute Assistant Professor
  • 2017/04 - 2021/05 Tokyo Medical and Dental University Medical Research Institute Pathophysiology Pathological Cell Biology Assistant Professor
  • 2016/12/01 - 2017/03/31 Tokyo Medical and Dental University Medical Research Institute Pathophysiology Pathological Cell Biology Project Assistant Professor
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Association Membership(s) (2):
日本臨床ストレス応答学会 ,  分子生物学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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