Naito Mitsuru

ナイトウミツル | Naito Mitsuru

Affiliation and department：
Job title： Senior Lecturer
Homepage URL (1)： http://www.bmm.t.u-tokyo.ac.jp

Research field (5)： Polymer chemistry , Nanobioscience , Biomaterials , Biomedical engineering , Medical systems

Research keywords (8)：心疾患 , 筋疾患 , 生体高分子 , gene therapy , polyion complex , polymeric micelle , oligonucleotide therapeutics , Drug Delivery System

Research theme for competitive and other funds (12)：

2024 - 2028 サイズの精密制御に基づく薬物送達システムの設計と脳腫瘍に対するX線治療への展開
2024 - 2027 微生物による分解を必要としない海洋分解性高分子の開発とマテリアルリサイクル可能なセルロースナノファイバー複合材料への展開
2023 - 2024 粘膜免疫を誘導可能なmRNAワクチンの開発
2021 - 2022 Fablication of antigen presenting cell targeting delivery system to modulate intracellular STING pathway
2021 - 2022 Design and synthesis of dynamic crosslinkable polymers for controlling their viscoelasticity and establishment of large-scale synthesis method

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Papers (56)：

Mohit J. Mehta, Hyun Jin Kim, Sung Been Lim, Mitsuru Naito, Kanjiro Miyata. Recent Progress in the Endosomal Escape Mechanism and Chemical Structures of Polycations for Nucleic Acid Delivery. Macromolecular Bioscience. 2024
Ryunosuke Kobayashi, Mitsuru Naito, Kanjiro Miyata, Takamasa Sakai, Ung-il Chung, Takuya Katashima. Predicting the effects of degradation on viscoelastic relaxation time using model transient networks. Polymer Journal. 2024
Jongmin Yum, Fadlina Aulia, Keisuke Kamiya, Mao Hori, Nan Qiao, Beob Soo Kim, Mitsuru Naito, Satomi Ogura, Tetsuya Nagata, Takanori Yokota, et al. Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery. Bioconjugate Chemistry. 2024
Kunihiko Morihiro, Shunto Morita, Naoki Harada, Manami Baba, Jongmin Yum, Mitsuru Naito, Kanjiro Miyata, Genta Nagae, Akimitsu Okamoto. RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality. Journal of the American Chemical Society. 2024
Kento Fujiura, Mitsuru Naito, Yukiko Tanaka, Masaru Tanaka, Yurie Nakanishi, Hirotaka Ejima, Lumi Negishi, Tomoya Kujirai, Hitoshi Kurumizaka, Seiichi Ohta, et al. Development of stealth nanoparticles coated with poly(2-methoxyethyl vinyl ether) as an alternative to poly(ethylene glycol). Journal of Applied Polymer Science. 2023. 141. 11

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MISC (15)：

内藤瑞. “DDSの「ちょっとした」技術・知識”第18回縮合反応のちょっとしたコツ有機溶媒中でのアミン-アルボン酸縮合反応. Drug Delivery System. 2023. 38. 1
内藤瑞. 核酸医薬のDDS(drug delivery system)リガンドコンジュゲートによる受容体介在デリバリー. Clinical Neuroscience. 2023. 41. 5
野呂美穗子, 内藤瑞, 原倫太朗, 横田隆徳, 宮田完二郎. Fluoroalkyl-modified Nanoparticles as Stabilized Nanocarriers for Oligonucleotide Therapeutics. AGC Research Report. 2022. 72
内藤瑞. Recent advances in oligonucleotide delivery systems. 野口研究所時報. 2022. 65
内藤瑞, 宮田完二郎. Cationic polypeptide design for polyion complex-mediated mRNA delivery. Drug Delivery System. 2022. 37. 3

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Patents (13)：

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Books (3)：

Drug Delivery Systems for Musculoskeletal Tissues
2024 ISBN:3031556526
刺激応答性高分子ハンドブック
エヌ・ティー・エス 2018 ISBN:9784860435356
DDS先端技術の製剤への応用開発
技術情報協会 2017 ISBN:4861046637

Education (2)：

2010 - 2015 The University of Tokyo Graduate School of Engineering Department of Materials Engineering
2006 - 2010 The University of Tokyo School of Engineering Department of Materials Engineering

Professional career (1)：

博士(工学) (東京大学)

Work history (5)：

2023/09 - 現在 The University of Tokyo The Graduate School of Engineering
2022/04 - 2023/08 The University of Tokyo The Graduate School of Engineering Assistant professor
2019/04 - 2022/03 The University of Tokyo Graduate School of Medicine
2015/04 - 2019/03 The University of Tokyo Graduate School of Medicine Postdoctoral Researcher
2013/04 - 2015/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists (DC2)

Committee career (2)：

2023/08 - 現在次世代医工学研究会世話人
2023/04 - 現在関東高分子若手研究会世話人

Awards (10)：

2022/09 - 第27回創剤フォーラム若手研究会最優秀発表賞
2019/02 - 平成30年度手島記念研究賞(研究論文賞)
2018/11 - Japan Society for Biomaterials Japanese and Korean Biomaterials Societies Young Scientist Exchange Program Award (2018)
2018/01 - 27th intelligent materials/system symposium The Takagi Award
2017/11 - The 2nd International Symposium on Biomedical Engineering Young Researchers Poster Award

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Association Membership(s) (5)：

THE JAPANESE SOCIETY FOR BIOMATERIALS , THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM , THE SOCIETY OF POLYMER SCIENCE, JAPAN , 日本筋学会 , NUCLEIC ACIDS THERAPEUTICS SOCIETY OF JAPAN

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