Rchr
J-GLOBAL ID:201801006150391330   Update date: Feb. 01, 2024

Chieko Ishifune

イシフネ チエコ | Chieko Ishifune
Affiliation and department:
Homepage URL  (1): http://immunology.hosp.med.tokushima-u.ac.jp/immunology/system/top/
Research field  (1): Immunology
Research keywords  (6): 免疫学 ,  Notch ,  分化 ,  腸管上皮間リンパ球 ,  樹状細胞 ,  マクロファージ
Research theme for competitive and other funds  (7):
  • 2025 - 2028 TCRγδ型腸管上皮間リンパ球サブセットの解明・腸病態制御に関する研究
  • 2023 - 2026 シングルセル解析技術を用いたNotch介在性の小腸上皮間リンパ球多様性獲得機序の解明
  • 2024 - 2025 Notchシグナルによる腸管上皮間リンパ球の多様なサブセットの制御に関する研究
  • 2018 - 2023 Notchシグナルによる小腸上皮間リンパ球の成熟・TCRレパトア調節機構の解明
  • 2015 - 2018 Notchシグナルによる小腸上皮間リンパ球の制御を介した腸管恒常性維持機構の解明
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Papers (19):
  • Thiranut Jaroonwitchawan, Hideki Arimochi, Yuki Sasaki, Chieko Ishifune, Hiroyuki Kondo, Kunihiro Otsuka, Shin-ichi Tsukumo, Koji Yasutomo. Stimulation of the farnesoid X receptor promotes M2 macrophage polarization. Frontiers in Immunology. 2023. 14
  • Shin-ichi Tsukumo, Poorani Ganesh Subramani, Noé Seija, Mizuho Tabata, Yoichi Maekawa, Yuya Mori, Chieko Ishifune, Yasushi Itoh, Mineto Ota, Keishi Fujio, et al. AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination. Science Advances. 2022. 8. 34
  • Chieko Ishifune, Shin-Ichi Tsukumo, Yoichi Maekawa, Katsuto Hozumi, Doo Hyun Chung, Chihiro Motozono, Sho Yamasaki, Hiroyasu Nakano, Koji Yasutomo. Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells. PLoS biology. 2019. 17. 5. e3000262
  • Taskia Sultana Zaman, Hideki Arimochi, Satoshi Maruyama, Chieko Ishifune, Shin-ichi Tsukumo, Akiko Kitamura, Koji Yasutomo. Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression. JOURNAL OF IMMUNOLOGY. 2017. 199. 6. 1989-1997
  • Masanori Niki, Kohei Nakajima, Daichi Ishikawa, Jun Nishida, Chieko Ishifune, Shin-ichi Tsukumo, Mitsuo Shimada, Shinji Nagahiro, Yoshinori Mitamura, Koji Yasutomo. MicroRNA-449a deficiency promotes colon carcinogenesis. SCIENTIFIC REPORTS. 2017. 7. 1. 10696
more...
MISC (7):
Books (1):
  • Notch and Myeloid Cells
    Springer 2017
Lectures and oral presentations  (33):
  • Notch signal controls final differentiation of TCRgd+CD8aa+ intraepithelial lymphocytes in the small intestine
    (The 51st Annual Meeting of The Japanease Society for Immunology 2022)
  • Notch-mediated final differentiation of TCRgd+CD8aa+ intraepithelial lymphocyte in the small intestine
    (The 47th Annual Meeting of The Japanease Society for Immunology 2018)
  • Notch signal controls TCRγδ+CD8αα+ intestinal intraepithelial lymphocyte
    (7th Joint Meeting of Tokushima University, Gifu University, KAIST, and Seoul National University 2018)
  • Notch signal controls the number of TCRαβ+CD8αα+ intraepithelial lymphocytes via phospholipid asymmetry by maintaining flippase ATP8a2
    (Australia-Japan Meeting on Cell Death 2018)
  • Notch signal controls the number of TCRαβ+CD8αα+ intraepithelial lymphocytes via phospholipid asymmetry by maintaining flippase ATP8a2
    (第46回日本免疫学会学術集会 2017)
more...
Education (3):
  • 2007 - 2011 The University of Tokushima Graduate School of Medical Sciences
  • 2005 - 2007 The University of Tokushima Graduate School of Medical Sciences
  • 2001 - 2005 The University of Tokushima Faculty of Engineering Department of Biological Science and Technology
Professional career (2):
  • 医科学修士 (徳島大学)
  • PhD (The University of Tokushima)
Work history (4):
  • 2015/04 - 現在 徳島大学大学院 医歯薬学研究部 生体防御医学 (大学院名称変更に伴う)
  • 2012/04 - 2015/03 徳島大学 大学院ヘルスバイオサイエンス研究部 生体防御医学 助教
  • 2011/04 - 2012/03 Japan Society for the Promotion of Science
  • 2010/04 - 2011/03 Japan Society for the Promotion of Science
Awards (4):
  • 2023/09 - 日本免疫学会 2023年若手女性研究者研究支援事業 Notchシグナルによる腸管上皮間リンパ球の多様なサブセットの制御に関する研究
  • 2016/06 - Japanese Society for Immunology Novo Nordisk International Travel Bursary for the 16th International Congress of Immunology (ICI) Notch-STAT5b is central for the development of TCRαβ+CD8αα+ small intestinal intraepithelial lymphocytes
  • 2015/11 - Tokushima University 若手研究者学長表彰
  • 2006/09 - 徳島大学大学院ヘルスバイオサイエンス研究部 第2回 Tokushima Bioscience Retreat ベストプレゼンテーション賞 Notchシグナル誘導性の新規樹状細胞の免疫応答における役割
Association Membership(s) (1):
THE JAPANESE SOCIETY FOR IMMUNOLOGY
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