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Affiliation and department：
Research theme for competitive and other funds (4)：
Papers (13)：
MISC (15)：
Patents (4)：
Books (2)：
Lectures and oral presentations (22)：
Association Membership(s) (2)：
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About -
Research theme for competitive and other funds (4)：
- 2022 - 2025 NLRP3インフラマソーム阻害作用を持つ天然物を活用した創薬研究への展開
- 2019 - 2022 Research on drug development utilizing natural products with both anti-NLRP3 inflammasome and anti-fibrosis properties
- 2015 - 2018 Search for the target molecule of the licorice component inhibiting NLRP3 inflammasome and development into drug discovery research
- 2005 - 2009 Enhancement of Th1 and antitumor immunity by Ag85B and Peptide-25.
- Fumitake Usui-Kawanishi, Koudai Kani, Tadayoshi Karasawa, Hiroe Honda, Nobuyuki Takayama, Masafumi Takahashi, Kiyoshi Takatsu, Yoshinori Nagai. Isoliquiritigenin inhibits NLRP3 inflammasome activation with CAPS mutations by suppressing caspase-1 activation and mutated NLRP3 aggregation. Genes to cells : devoted to molecular & cellular mechanisms. 2024. 29. 5. 423-431
- Yuki Tada, Kaichi Kasai, Nana Makiuchi, Naoya Igarashi, Koudai Kani, Shun Takano, Hiroe Honda, Tsutomu Yanagibashi, Yasuharu Watanabe, Fumitake Usui-Kawanishi, et al. Roles of Macrophages in Advanced Liver Fibrosis, Identified Using a Newly Established Mouse Model of Diet-Induced Non-Alcoholic Steatohepatitis. International journal of molecular sciences. 2022. 23. 21
- Riko Ishibashi, Yukihiro Furusawa, Hiroe Honda, Yasuharu Watanabe, Shiho Fujisaka, Miyu Nishikawa, Shinichi Ikushiro, Shin Kurihara, Yoshiaki Tabuchi, Kazuyuki Tobe, et al. Isoliquiritigenin Attenuates Adipose Tissue Inflammation and Metabolic Syndrome by Modifying Gut Bacteria Composition in Mice. Molecular Nutrition & Food Research. 2022. 66. 10. 2101119-2101119
- Masaru Ogasawara, Shino Yamasaki-Yashiki, Masahiro Hamada, Tomomi Yamaguchi-Miyamoto, Toru Kawasuji, Hiroe Honda, Tsutomu Yanagibashi, Masashi Ikutani, Yasuharu Watanabe, Ryota Fujimoto, et al. Betulin Attenuates TGF-β1- and PGE<sub>2</sub>-Mediated Inhibition of NK Cell Activity to Suppress Tumor Progression and Metastasis in Mice. Biological and Pharmaceutical Bulletin. 2022. 45. 3. 339-353
- Watanabe Y, Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, et al. Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019. 33. 11. 11821-11835
- Hidemasa NAGAI, Hiroe HONDA, Masayuki HAYASHI, The Drug Formulation, Study Group, in Toyama, Pharmaceutical Research Association. Development of Design Space in Twin-screw Type Granulation (The Second Report). ANNUAL REPORT OF TOYAMA PREFECTURAL INSTITUTE FOR PHARMACEUTICAL RESEARCH. 2024. 51. 18-22
- Hidemasa NAGAI, Hiroe HONDA, Masayuki HAYASHI, The Drug Formulation, Study Group, in Toyama, Pharmaceutical Research Association. Development of Design Space in Twin-screw Type Granulation. ANNUAL REPORT OF TOYAMA PREFECTURAL INSTITUTE FOR PHARMACEUTICAL RESEARCH. 2023. 50. 19-24
- Takeharu MINAMITANI, Hiroe HONDA, Tsutomu YANAGIBASHI, Yasuharu WATANABE, Rieko KOJIMA, Yukihiko AIKAWA and the Biological Analysis Group in Toyama Pharmaceutical Research Association. Analysis of blood concentrations of antibody drugs using LC-MS/MS. ANNUAL REPORT OF TOYAMA PREFECTURAL INSTITUTE FOR PHARMACEUTICAL RESEARCH. 2023. 50. 25-32
- Rieko KOJIMA, Hideo OGISO, Hiroe HONDA, Tomomi MIYAMOTO, The Biological Analysis Group in Toyama Pharmaceutical Research Association. Characterization and similarity comparison of biopharmaceuticals. ANNUAL REPORT OF TOYAMA PREFECTURAL INSTITUTE FOR PHARMACEUTICAL RESEARCH. 2022. 49. 25-34
- MIYAMOTO T, MATSUNAGA T, HONDA H, YANAGIBASHI T, OGASAWARA M, TAKAYAMA N, AIKAWA Y, KAWASHIRI C, The Biological, Study Group, et al. Quality evaluation of biopharmaceuticals- Examination of Comparability of biosimilar -. 2019. 46. 24-27
- カンゾウエキス及びその製造方法、並びに、腸内細菌調整用組成物、腸管バリア機能増強組成物、抗肥満用組成物、抗糖尿病用組成物、及びNLRP3インフラマソーム活性制御用組成物
- 粘膜アジュバント
- 自然免疫を活性化する粘膜ワクチン用アジュバント
- インフラマソーム活性制御剤
- Biological activities and action mechanisms of licorice ingredients (ed. H. Sakagami)
InTech 2017 ISBN:9789535131199 - Chronic Inflammation -Mechanisms and Regulation-(M. Miyasaka and K. Takatsu)
Springer Japan 2016
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Isoliquiritigenin inhibits activation of NLRP3 inflammasome with CAPS mutations by suppressing caspase-1 activation and mutant NLRP3 aggregation
(2024) -
Effect of isoliquiritigenin on gut bacteria, adipose tissue inflammation, and metabolic syndrome
(2022) -
Effect of isoliquiritigenin on gut bacteria, adipose tissue inflammation, and metabolic syndrome
(2022) -
A licorice-derived ingredient ameliorates metabolic syndrome through the alteration of gut microbiota
(第50回日本免疫学会学術集会 2021) -
Analysis of Inhibitory Effect of Isoliquiritigenin on NLRP3 Inflammasome Activation
(2018)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.
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