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J-GLOBAL ID：201801007281025395 Update date: Mar. 29, 2025

Shimizu Tomohiro

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Affiliation and department：
Job title： Associate Professor

Research field (1)： Orthopedics

Research keywords (6)：整形外科 , 股関節外科 , 骨粗鬆症 , 人工知能 , 関節リウマチ , スポーツ医学

Research theme for competitive and other funds (12)：

2023 - 2026 マクロファージ応答に着目した抗RANKL抗体のリバウンドのメカニズム解明とその対策
2023 - 2026 Exploring functional roles of osteal macrophages in bone metabolism for the development of osteoporosis therapeutics
2023 - 2026 Functional analysis of bone macrophages that control bone metabolism for the development of therapeutic drugs for osteoporosis.
2023 - 2026 特発性大腿骨頭壊死症における多発骨壊死発生とマイクロバイオーム異常の関連性
2022 - 2025 Elucidation of innate immune disorders that regulate joint destruction and joint degeneration after fracture

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Papers (97)：

Hirokazu Shimizu, Ken Enda, Hidenori Koyano, Takuya Ogawa, Daisuke Takahashi, Shinya Tanaka, Norimasa Iwasaki, Tomohiro Shimizu. Diagnosis on Ultrasound Images for Developmental Dysplasia of the Hip with a Deep Learning-Based Model Focusing on Signal Heterogeneity in the Bone Region. Diagnostics (Basel, Switzerland). 2025. 15. 4
Takuya Ogawa, Shunichi Yokota, Liyile Chen, Yuki Ogawa, Yoshio Nishida, Taiki Tokuhiro, Hend Alhasan, Tomoyo Yutani, Tomohiro Shimizu, Daisuke Takahashi, et al. Therapeutic Potential of Targeting Ferroptosis in Periprosthetic Osteolysis Induced by Ultra-High-Molecular-Weight Polyethylene Wear Debris. Biomedicines. 2025. 13. 1. 170-170
Yutaro Sugawara, Hotaka Ishizu, Kosuke Arita, Tetsuro Oue, Komei Sato, Renya Takahashi, Kenichi Kusunoki, Shun Shimodan, Tsuyoshi Asano, Norimasa Iwasaki, et al. Thoracolumbar kyphosis prognoses poor results after proximal femoral fracture: a 3-year multicenter prospective cohort study. Journal of bone and mineral metabolism. 2025
Qi Yao, Kanako Tsuboi, Hiromi Hongo, Mako Sakakibara, Tomomaya Yamamoto, Mai Haraguchi-Kitakamae, Hotaka Ishizu, Xuanyu Liu, Yan Shi, Weisong Li, et al. Histochemical assessment of the femora of Spontaneously Diabetic Torii-Leprfa (SDT-fa/fa) rats that mimic type II diabetes. Journal of oral biosciences. 2024. 100602-100602
Taiki Tokuhiro, Gen Matsumae, Tsutomu Endo, Yuki Ogawa, Takuya Ogawa, Chen Liyile, Yoshio Nishida, Hend Alhasan, Hideyuki Kobayashi, Taku Ebata, et al. Cellular communication network factor 3 contributes to the pathological process of rheumatoid arthritis through promoting cell senescence and osteoclastogenesis in the joint. Journal of autoimmunity. 2024. 149. 103334-103334

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MISC (406)：

濱井敏, 藤元祐介, 山口亮介, 上原悠輔, 原大介, 清水智弘, 細山嗣晃, 星野裕信, 中島康晴. 変形性関節症ガイドラインのアップデート変形性股関節症ガイドラインのアップデート(関節温存術). 日本関節病学会誌. 2024. 43. 2. 138-138
石津帆高, 清水智弘, 長谷川智香, 網塚憲生, 岩崎倫政. DAP12/TREM2 signalはRANKL中和抗体中止後の過剰な骨吸収に影響を及ぼす. 日本骨形態計測学会雑誌. 2024. 34. 1. 117-117
石津帆高, 清水智弘, 北原圭太, 高山寛己, 宮本守孝, 岩崎倫政. DXAにおいて影響を及ぼし得る体内アーチファクトに対するREMSの有用性検討. 日本骨形態計測学会雑誌. 2024. 34. 1. 129-129
濱井敏, 藤元祐介, 山口亮介, 上原悠輔, 原大介, 清水智弘, 細山嗣晃, 星野裕信, 中島康晴. エビデンスに基づいた変形性股関節症診療-ガイドライン第3版- (第5章)『関節温存術』改訂のポイント. 日本整形外科学会雑誌. 2024. 98. 2. S514-S514
浅野毅, 芝山浩樹, 有田皓介, 伊藤華奈子, 泉泰純, 清水智弘, 高橋大介, 岩崎倫政. 大腿骨近位部骨折患者における重症骨粗鬆症の有病率 3年間322症例の解析から. 日本整形外科学会雑誌. 2024. 98. 2. S105-S105

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Patents (2)：

Education (2)：

2012 - 2016 Hokkaido University Graduate School of Medicine
2001 - 2007 Hokkaido University School of Medicine

Professional career (1)：

医学博士 (北海道大学)

Work history (11)：

2024/04 - 現在 Hokkaido University Hospital Department of Orthopaedic Surgery Associate Professor
2023/04 - 現在 Hokkaido University
2018/11 - 2024/03 Hokkaido University Hospital Assistant professor
2018/04 - 2018/10 北海道大学病院整形外科医員
2016/10 - 2018/03 University of California, San Francisco

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Committee career (2)：

2024/06 - 現在日本整形外科学会代議員選挙管理委員
2024/06 - 現在日本整形外科学会男女共同参画委員

Awards (22)：

2024 - 日本股関節学会第51回日本股関節学会優秀演題賞
2023 - 日本整形外科学会日整会Travelling Fellowship(Korean Orthopaedic Association Annual Congress)
2022 - 北海道大学整形外科松田嘉博先生学術奨学金学術奨励賞
2022 - 日本医師会研究奨励賞
2022 - 北海道大学医学部医学研究院エクセレントティーチャー

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