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J-GLOBAL ID：201801007453491466 Update date: Feb. 14, 2025

NEGISHI Takefumi

ネギシタケフミ | NEGISHI Takefumi

Affiliation and department：
Job title： Assistant Professor
Homepage URL (2)： http://square.umin.ac.jp/Nemalab/Home.html , http://db.tohoku.ac.jp/whois/e_detail/8ab2051ed0c53edefec029e5367776e1.html

Research field (1)： Developmental biology

Research keywords (4)：線虫 , Marine invertebrate , Cell biology , Developmental biology

Research theme for competitive and other funds (10)：

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Papers (14)：

Moutushi Islam, Takefumi Negishi, Naomi Kitamoto, Yuki Hatoyama, Kanae Gamo, Ken-ichiro Hayashi, Masato T. Kanemaki. A single-chain antibody-based AID2 system for conditional degradation of GFP-tagged and untagged proteins. 2025
Réda M. Zellag, Vincent Poupart, Takefumi Negishi, Jean-Claude Labbé, Abigail R. Gerhold. The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in theC. elegansgerm line. Cell Reports. 2024. 44. 2. 115296-115296
Takefumi Negishi, Saho Kitagawa, Natsumi Horii, Yuka Tanaka, Nami Haruta, Asako Sugimoto, Hitoshi Sawa, Ken-ichiro Hayashi, Masahiko Harata, Masato T Kanemaki. The auxin-inducible degron 2 (AID2) system enables controlled protein knockdown during embryogenesis and development in Caenorhabditis elegans. Genetics. 2022. 220. 2
Ulla-Maj Fiuza, Takefumi Negishi, Alice Rouan, Hitoyoshi Yasuo, Patrick Lemaire. A Nodal/Eph signalling relay drives the transition from apical constriction to apico-basal shortening in ascidian endoderm invagination. Development (Cambridge, England). 2020. 147. 15
Takefumi Negishi, Masayo Asakawa, Masato T Kanemaki, Hitoshi Sawa. Modified auxin improves the auxin-inducible degradation (AID) system for laid C. elegans embryos. microPublication Biology. 2019

MISC (5)：

Réda M. Zellag, Vincent Poupart, Takefumi Negishi, Jean-Claude Labbé, Abigail R. Gerhold. The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in theC. elegansgerm line. 2024
根岸剛文. ホヤと線虫. 日仏生物学会誌. 2022. 61. 36-41
Ulla-Maj Fiuza, Takefumi Negishi, Alice Rouan, Hitoyoshi Yasuo, Patrick Lemaire. A Nodal/Eph signalling relay drives the transition from apical constriction to apico-basal shortening in ascidian endoderm invagination. 2018
Naoto Ueno, Takefumi Negishi. A novel membrane invagination controls oriented cell division in ascidian embryo. MECHANISMS OF DEVELOPMENT. 2017. 145. S4-S5
H. Nishida, Y. Nakamura, T. Negishi. Role of localized maternal mRNAs in eggs of a basal chordate, the ascidian Halocynthia roretzi. MECHANISMS OF DEVELOPMENT. 2005. 122. S26-S26

Patents (1)：

Lectures and oral presentations (12)：

Ror1/CAM-1 receptor cooperates with Frizzled/MOM-5 receptor in the Wnt signaling during C. elegans embryogenesis.
(2022)
胚発生中の細胞分裂制御メカニズムの解析
(195回日仏生物学会例会 2021)
Global regulation of cell polarization by two Wnt receptors, Frizzled/MOM-5 and Ror1/CAM-1 in C. elegans mid-stage embryo
(2021)
The auxin-inducible degron 2 (AID2) system provides sharp degradation control with low ligand concentrations and works at all developmental stages of C. elegans
(2021)
Global regulation of cell polarization by two Wnt receptors in C. elegans cleavage stage embryo
(2021)

Professional career (1)：

Awards (1)：

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