Rchr
J-GLOBAL ID:201801007729942815
Update date: Feb. 14, 2024
MUNESUE Seiichi
ムネスエ セイイチ | MUNESUE Seiichi
Affiliation and department:
Job title:
Assistant Professor
Research field (1):
Medical biochemistry
Research keywords (3):
糖尿病
, がん
, 生化学
Research theme for competitive and other funds (10):
- 2021 - 2024 愛情ホルモン・オキシトシンによる炎症免疫抑制作用の分子基盤の解明
- 2020 - 2023 RAGE膜貫通ドメインによる細胞膜ダイナミクスとがん悪性化シグナルの解明
- 2018 - 2021 Understanding of pathophysiological mechanisms and development of the treatment of schizophrenia based on novel gene polymorphisms of glyoxalase 1.
- 2018 - 2021 Investigation of molecular devices for oxytocin transport into the brain
- 2015 - 2018 Establishment of osteosarcoma stem cell model induced by RAGE and elucidation of its molecular mechanism
- 2014 - 2017 Identification of RAGE inhibitory components in foods and elucidation of its inhibitory mechanism
- 2013 - 2016 To unveil mechanisms triggering pancreatic beta cell dysfunction in type 2 diabetes possibly via RAGE, glucolipotoxicity and insufficient leptin signaling.
- 2011 - 2013 Identifying challenges to discover cancer stem-like cells in osteosarcoma
- 2009 - 2011 A novel signal reception mechanism by oligomerization of RAGE and gamma-secretase
- 2007 - 2010 Genesis and physiologic significance of secretory RAGE-a new vasoprotective factor
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Papers (71):
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Hiroaki Sugita, Shinichi Nakanuma, Seiichi Munesue, Tatsuya Ishikawa, Tomokazu Tokoro, Ryohei Takei, Mitsuyoshi Okazaki, Kaichiro Kato, Satoshi Takada, Isamu Makino, et al. Cilostazol improves the prognosis after hepatectomy in rats with sinusoidal obstruction syndrome. Journal of gastroenterology and hepatology. 2024
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Masakazu Saeki, Seiichi Munesue, Yuri Higashi, Ai Harashima, Ryohei Takei, Satoshi Takada, Shinichi Nakanuma, Tetsuo Ohta, Shintaro Yagi, Hidehiro Tajima, et al. Assaying ADAMTS13 Activity as a Potential Prognostic Biomarker for Sinusoidal Obstruction Syndrome in Mice. International journal of molecular sciences. 2023. 24. 22
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Tatsuya Aoki, Jun Kinoshita, Seiichi Munesue, Toshihide Hamabe-Horiike, Takahisa Yamaguchi, Yusuke Nakamura, Koichi Okamoto, Hideki Moriyama, Keishi Nakamura, Shinichi Harada, et al. ASO Visual Abstract: Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake. Annals of surgical oncology. 2023
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Takashi Higuchi, Akihiko Takeuchi, Seiichi Munesue, Norio Yamamoto, Katsuhiro Hayashi, Ai Harashima, Yasuhiko Yamamoto, Hiroyuki Tsuchiya. A nonsteroidal anti-inflammatory drug, zaltoprofen, inhibits the growth of extraskeletal chondrosarcoma cells by inducing PPARγ, p21, p27, and p53. Cell Cycle. 2023. 22. 8. 1-12
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Tatsuya Aoki, Jun Kinoshita, Seiichi Munesue, Toshihide Hamabe-Horiike, Takahisa Yamaguchi, Yusuke Nakamura, Koichi Okamoto, Hideki Moriyama, Keishi Nakamura, Shinichi Harada, et al. Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake. Annals of surgical oncology. 2022
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MISC (30):
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丸銭 祥吾, 田島 秀浩, 山本 靖彦, 棟居 聖一, 岡崎 充善, 大畠 慶直, 真橋 宏幸, 中沼 伸一, 牧野 勇, 八木 真太郎. 膵神経内分泌腫瘍治療の新たな展開 膵神経内分泌腫瘍細胞株(QGP-1)へのメトホルミン投与による細胞増殖抑制効果の検討. 日本消化器外科学会総会. 2021. 76回. O32-1
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新村朱子, 木下結衣, 原島愛, 棟居聖一, 木村久美, LEERACH Nontaphat, 大島由, 林謙次郎, 田中麻莉子, 後藤久典, et al. Visualization of protein glycation using the atomic force microscopy. 日本メイラード学会年会プログラム・抄録集. 2021. 31st (CD-ROM)
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樋口 貴史, 山本 憲男, 林 克洋, 武内 章彦, 阿部 健作, 谷口 裕太, 相羽 久輝, 荒木 麗博, 原島 愛, 棟居 聖一, et al. ZaltoprofenはPPARγを介して軟骨肉腫の増殖を抑制する. 日本癌治療学会学術集会抄録集. 2017. 55回. P41-1
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樋口 貴史, 武内 章彦, 土屋 弘行, 山本 靖彦, 棟居 聖一. 整形トピックス ザルトプロフェンはPPARγを介して軟骨肉腫における浸潤能および遊走能の抑制効果を発揮する. 整形外科. 2017. 68. 10. 1082-1082
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樋口 貴史, 山本 憲男, 林 克洋, 武内 章彦, 阿部 健作, 谷口 裕太, 原島 愛, 棟居 聖一, 山本 靖彦, 土屋 弘行. Zaltoprofenはin vitroとin vivoにおいてPPARγを介して軟骨肉腫の増殖を抑制する. 日本整形外科学会雑誌. 2017. 91. 8. S1527-S1527
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Professional career (1):
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