Miura Kazuki

ミウラカズキ | Miura Kazuki

Affiliation and department：
Homepage URL (1)： http://syn.res.titech.ac.jp

Research field (4)： Chemical biology , Pharmaceuticals - chemistry and drug development , Bioorganic chemistry , Functional biochemistry

Research keywords (8)： Chemical Biology , Medicinal Chemistry , Bioorganic Chemistry , Biochemistry , 糖質化学 , Photodynamic Therapy , Natural Product Drug Discovery , Glycan Processing

Research theme for competitive and other funds (8)：

2024 - 2027 MRIプローブによる記憶形成メカニズムの解明
2024 - 2026 Development of molecular-targeted photodynamic therapy by light-inactivation of cancer specific proteins
2021 - 2025 Development of Endogenous Albumin-Based Novel Boron Delivery System
2022 - 2024 神経活動履歴を可視化する磁性ナノプローブの開発
2022 - 2024 Development of 3D skeleton compound library targeting protein-protein interaction

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Papers (36)：

Mai Kawaguchi, Hiroshi Aoki, Hiroki Kamo, Kazuki Miura, Yuki Hiruta, Siro Simizu, Daniel Citterio. Simplified capture, extraction, and amplification of cellular DNA from water samples. Analytical Sciences. 2023. 40. 3. 501-510
Manjot Kaur, Ramovatar Meena, Kai Nishimura, Kazuki Miura, Hiroyuki Nakamura, Minoru Suzuki, Ram K. Sharma, Akshay Kumar. Boron neutron capture therapy anti-tumor effect of nanostructured boron carbon nitride: A new potential candidate. Inorganic Chemistry Communications. 2023. 157. 111318-111318
Tomoya Doi, Kohei Umedera, Kazuki Miura, Taiki Morita, Hiroyuki Nakamura. Synthesis of diazatricycloundecane scaffold via gold(I)-catalysed Conia-ene-type 5-<i>exo-dig</i> cyclization and stepwise substituent assembly for construction of sp<sup>3</sup>-rich compound library. Organic & Biomolecular Chemistry. 2023
Kazuki Miura, Manjusha Joshi, Taiki Morita, Hiroyuki Nakamura. Discovery of three-dimensional bicyclo[3.3.1]nonanols as novel heat shock protein 90 inhibitors. Bioorganic & Medicinal Chemistry. 2023. 93. 117463-117463
Kai Nishimura, Hideki Kashiwagi, Taiki Morita, Yusuke Fukuo, Satoshi Okada, Kazuki Miura, Yoshitaka Matsumoto, Yu Sugawara, Takayuki Enomoto, Minoru Suzuki, et al. Efficient neutron capture therapy of glioblastoma with pteroyl-closo-dodecaborate-conjugated 4-(p-iodophenyl)butyric acid (PBC-IP). Journal of Controlled Release. 2023. 360. 249-259

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MISC (2)：

三浦一輝, 袴田航, 平野貴子, 西尾俊幸. Da-6 β-グリコシダーゼのタンパク質糖鎖修飾酵素としての可能性(糖質関連酵素,一般講演,一般社団法人日本応用糖質科学会平成27年度大会(第64回)). 応用糖質科学 : 日本応用糖質科学会誌. 2015. 5. 3. B53
三浦一輝, 袴田航, 平野貴子, 西尾俊幸. Cp-1 ゴルジ体に局在する新規β-アロシダーゼ活性 : 光アフィニティーラベル法による標的酵素の同定(糖質の構造・合成-2,一般講演,日本応用糖質科学会平成26年度大会(第63回)). 応用糖質科学 : 日本応用糖質科学会誌. 2014. 4. 3. B48

Lectures and oral presentations (50)：

Development of novel small molecule boron carriers targeting the amino acid transporter ASCT2
(19th Annual Conference of The Japanese Society of Neutron Capture Therapy 2023)
Molecular-targeted photodynamic therapy based on light-inactivation of cancer-specific molecule
(27th Annual Conference of The Japanese Association for Molecular Target Therapy of Cancer 2023)
Development of cancer specific molecular-targeted photodynamic therapy as a novel photodynamic therapy strategy
(17th Annual Conference of the Japanese Society for Chemical Biology 2023)
Development of novel bioactive compounds with bicyclo[3.3.1]nonane scaffold and elucidation of its mechanism of action
(The 143rd Annual Meeting of the Pharmaceutical Society of Japan 2023)
Development of intracellular molecular targeted photodynamic therapy as a novel photodynamic therapy strategy
(Future Drug Discovery Empowered by Chemical Biology 2023)

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Education (2)：

2013 - 2018 日本大学大学院生物資源科学研究科
2009 - 2013 Nihon University College of Bioresource Sciences Department of Chemistry and Life Science

Professional career (1)：

博士(生物資源科学) (日本大学)

Work history (3)：

2024/10 - 現在 Institute of Sciecne Tokyo Laboratory for Chemistry and Life Science, Institute of Integrated Research Assistant professor
2021/04 - 2024/09 Tokyo Institute of Technology Laboratory for Chemistry and Life Science, Institute of Innovative Research Assistant Professor
2018/04 - 2021/03 Keio university Department of Applied Chemistry, Faculty of Science and Technology Research Associate

Awards (8)：

2023/07 - Japanese Society of Neutron Capture Therapy 19th Annual Conference of The Japanese Society of Neutron Capture Therapy Poster Award Development of novel small molecule boron carrier targeting amino acid transporter ASCT2
2023/06 - Japanese Association for Molecular Target Therapy of Cancer 27th Annual Conference of The Japanese Association for Molecular Target Therapy of Cancer Poster Award Molecular-targeted photodynamic therapy based on light-inactivation of cancer-specific molecule
2022/07 - The Japanese Association for Molecular Target Therapy of Cancer 26th Annual Conference of The Japanese Association for Molecular Target Therapy of Cancer Poster Award Target protein specific inactivation and anti-tumor effect with ligand-conjugated organic photosensitizers
2021/06 - Japanese Society for Chemical Biology 15th Annual Conference of the Japanese Society for Chemical Biology Poster Award Development of photocatalytic-proximity protein labeling for intracellular protein-protein interaction analysis
2018/07 - 日本応用糖質科学会東日本支部平成30年度日本応用糖質科学会東日本支部若手奨励賞精密分子設計に基づく蛍光基質の開発とそれを用いた新規糖質加水分解酵素の探索と同定

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Association Membership(s) (6)：

INTERNATIONAL CHEMICAL BIOLOGY SOCIETY , THE JAPANESE SOCIETY OF APPLIED GLYCOSCIENCE , JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , The Japanese Association for Molecular Target Therapy of Cancer

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