2020 - 2023 A new drug-delivery method to the central nervous system: study on novel proteins that regulate drug-permeability in the blood-brain barrier
2020 - 2023 A hydrogen isotope separation method based on the Ludwig-Soret effect
2020 - 2023 神経活動リズムを形成する過分極応答解析のためのイメージングデバイス開発
2019 - 2023 An ALS2-linked functional cellular network-based study on molecular mechanisms of selective upper motor neuron degeneration in ALS
2018 - 2023 Ensuring integrity of gametogenesis
2018 - 2023 Establishment of in vitro spermatogenesis with high integrity
2018 - 2023 An integrated body-on-a-chip mimicking physiological parameters
2013 - 2018 In vitro system maintaining efficient spermatogenesis for a long duration
2015 - 2017 Development of an On-chip Simulator of Hepatic Lobule
2014 - 2017 Development of in vitro embryo culture system based-on microfluidics for artificial reproductive technology
2014 - 2017 Ischemic stroke therapy using quality and quantity-controlled culture system enriched in endothelial progenitor cells
2013 - 2015 細胞間相互作用の解明に向けたマイクロ流体プローブ集積型アッセイツールの構築
2009 - 2015 Behavioral analyses of genes and cells in early mammalian development
2012 - 2014 An on-chip hepatic metabolism model for pharmacokinetic studies
2010 - 2011 マイクロ流体技術を応用した哺乳類胚アッセイプラットフォームの構築
2010 - 2011 Integrated "Body on a Chip" system for cell-based assay
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Papers (93)：
Jyoti Jaiswal, Kazuma Sasaki, Kenta Shinha, Ganesh Kumar Mani, Hiroshi Kimura, Kazuyoshi Tsuchiya. Fabrication of microfluidic pH sensing chip based on sputtered Sb2O3/Sb thin film working electrode and AgIO3/Ag thin film reference electrode for detection of A549 cells. Measurement. 2024. 114781-114781
Dhimas Agung Kurniawan, Sylvia Leo, Mutsumi Inamatsu, Sohei Funaoka, Taichi Aihara, Mizuno Aiko, Inoue Rei, Takeshi Sakura, Hiroshi Arakawa, Yukio Kato, et al. Gut-liver microphysiological systems revealed potential crosstalk mechanism modulating drug metabolism. PNAS Nexus. 2024
Hiroshi Kimura, Hiroko Nakamura, Tomomi Goto, Wakana Uchida, Takayuki Uozumi, Daniel Nishizawa, Kenta Shinha, Junko Sakagami, Kotaro Doi. Standalone cell culture microfluidic device-based microphysiological system for automated cell observation and application in nephrotoxicity tests. Lab on a Chip. 2024. 24. 3. 408-421
Kikuo Komori, Shinnosuke Takumi, Kiichi Kato, Kazuya Matsumoto, Kohei Shiraishi, Hiroshi Kimura, Kazutake Takada. Direct electron transfer kinetics of histamine dehydrogenase at air plasma-treated graphite nanofibers. Journal of Electroanalytical Chemistry. 2023. 943. 117621-117621
Kiyoshi Hashimoto, Hisakazu Odaka, Yu Ishikawa-Yamauchi, Shino Nagata, Hiroko Nakamura, Hiroshi Kimura, Takuya Sato, Kazuhide Makiyama, Takehiko Ogawa. Culture-space control is effective in promoting haploid cell formation and spermiogenesis in vitro in neonatal mice. Scientific Reports. 2023. 13. 1
THE SOCIETY OF INSTRUMENT AND CONTROL ENGINEERS
, THE INSTITUTE OF ELECTRICAL ENGINEERS OF JAPAN
, THE SOCIETY FOR CHEMISTRY AND MICRO-NANO SYSTEMS
, THE JAPAN SOCIETY OF MECHANICAL ENGINEERS
, 日本動物実験代替法学会
