Sumitomo Tomoko

スミトモトモコ | Sumitomo Tomoko

Affiliation and department：
Job title： Professor

Research field (1)： Bacteriology

Research theme for competitive and other funds (31)：

2020 - 2023 インフルエンザウイルス感染に合併する細菌性肺炎の病態形成機構の解明と新規感染制御法の開発

2020 - 2023 一細胞解析による肺炎球菌感染時の宿主転写応答の解明

2019 - 2023 細菌における新規翻訳制御機構の探索

2021 - 2022 ウイルス感染に伴う上気道定着細菌のニッチ拡大と肺炎の病態形成を規定する宿主・細菌因子の探索

2019 - 2022 Molecular mechanisms underlying streptococcal infections for development of preventive and therapeutic measures

2019 - 2021 Investigation of novel infection control strategy based on bacterial evolutional information

2018 - 2020 Exploration of a novel dissemination route for development of therapeutic strategies against bacterial meningitis

2018 - 2020 トリセルラータイトジャンクションの破綻による劇症型レンサ球菌感染症の発症機構の解明

2017 - 2020 インフルエンザウイルス感染に続発する細菌性肺炎の重症化に寄与する宿主・細菌因子群の探索と新規感染制御法の開発

2017 - 2020 Analysis of interaction between streptococci and host during bacterial dissemination

2017 - 2020 トリセルラージャンクションを標的とする病原性レンサ球菌の組織侵入機構の解析

2016 - 2020 Molecular epidemiological analysis of Streptococcus pneumoniae in Southeast Asian countries

2017 - 2019 Exploration of pathogenicity caused by association and antigenicity of fibrous protein polymers present on the bacterial cell surface

2016 - 2018 Role of streptococcal arginie deiminase in the evasion of host immunity

2015 - 2018 Exploration of streptococcal factors related with onset of bacteremia and systemic dissemination

2014 - 2017 Analysis of expression mechanisms and adhesive functions of streptococal pili

2014 - 2017 Analysis of streptococcal translocation across epithelial barrier via paracellular route

2014 - 2016 Analysis of ornithine rhamnolipid-like pigment from oral bacteria

2012 - 2015 Exploration of bacterial factors that inactivate complement regulatory factors and induce invasive infectious diseases

2012 - 2014 Group A Streptococcus translocates across an epithelial barrier

2012 - 2014 Dvelopment of novel adjuvant which constructed by DNA origami technology

2012 - 2014 Role of cyclodextrin in oral bacteria-associated systemic illness

2011 - 2013 Analysis of virulence regulatory mechanism of group A streptococcal ncRNA

2008 - 2010 Functional analysis of adhesins and colonization factors produced by human pathogenic streptococci

2008 - 2009 Group A streptococci translocates across epithelial barrier via intercellular junction cleavage

2006 - 2007 Protective immunity against group Astreptococcus infection following immunization with fibronectin-binding proteins

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Papers (61)：

Tomoko Sumitomo, Shigetada Kawabata. Respiratory tract barrier dysfunction in viral-bacterial co-infection cases. Japanese Dental Science Review. 2024. 60. 44-52
Yuki Takahara, Tomoko Sumitomo, Masamitsu Kono, Moe Takemura, Yukako Akamatsu, Yujiro Hirose, Masaya Yamaguchi, Masanobu Nakata, Muneki Hotomi, Shigetada Kawabata. Pneumolysin contributes to dysfunction of nasal epithelial barrier for promotion of pneumococcal dissemination into brain tissue. mSphere. 2024. in press
Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, et al. Identifying Genetic Variations inemm89Streptococcus pyogenesLinked to Severe Invasive Infections. 2024
山口雅也, 東孝太郎, 武部克希, 中田匡宣, 住友倫子, 川端重忠. Structural analysis of inactive hyaluronidase of Streptococcus pyogenes(タイトル和訳中). 日本細菌学雑誌. 2024. 79. 2. 268-268
Dalia Talat, Tomoko Sumitomo, Mariko Honda-Ogawa, Yuki Takahara, Yasushi Mori, Masaya Yamaguchi, Masanobu Nakata, Madiha S. Ibrahim, Shigetada Kawabata. Two-component regulatory system TCS08 of a serotype 4 strain in pneumococcal pneumonia pathogenesis. Journal of Oral Biosciences. 2024. in press

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MISC (10)：

東孝太郎, 東孝太郎, 山口雅也, 中田匡宣, 武部克希, 住友倫子, 鈴木守, 川端重忠. Structural analysis of Streptococcus pyogenes hyaluronidase and in silico analysis based on structural models. Journal of Oral Biosciences Supplement (Web). 2021. 2021
大野誠之, 大野誠之, 山口雅也, 広瀬雄二郎, 東孝太郎, 東孝太郎, 秋山徹, 住友倫子, 池辺忠義, 山口貴弘, et al. Investigation of pathogenic mechanisms of invasive emm89 Streptococcus pyogenes infection with genome-wide k-mer association study. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
東孝太郎, 東孝太郎, 山口雅也, 中田匡宣, 中田匡宣, 武部克希, 住友倫子, 鈴木守, 川端重忠. 化膿レンサ球菌におけるヒアルロン酸分解酵素の分子系統解析および結晶構造解析. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
広瀬雄二郎, 山口雅也, 秋山徹, 竹本訓彦, 奥野ルミ, 山口貴弘, 大塚仁, 住友倫子, 中田匡宣, 川端重忠. Investigation of factors contributing to the invasiveness of Streptococcus pyogenes emm 89. 日本細菌学雑誌(Web). 2020. 75. 1
東孝太郎, 武部克希, 山口雅也, 住友倫子, 中田匡宣, 鈴木守, 川端重忠. 化膿レンサ球菌におけるヒアルロン酸分解酵素の分子系統解析およびタンパク質構造解析. Journal of Oral Biosciences Supplement (Web). 2018. 2018

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Education (3)：

2002 - 2005 The University of Tokushima Graduate School of Engineering
2000 - 2002 The University of Tokushima Graduate School of Engineering
1996 - 2000 The University of Tokushima Faculty of Engineering Department of Biological Science and Technology

Professional career (1)：

Work history (4)：

Awards (2)：

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