Hirokawa Yoshifumi

ヒロカワヨシフミ | Hirokawa Yoshifumi

Research field (1)： Experimental pathology

Research keywords (3)： Cell biology , Prostate cancer , Pathology

Research theme for competitive and other funds (10)：

2020 - 2023 膵癌における一次線毛の機能異常と臨床病理学的特性との連関
2019 - 2022 Development of a novel diagnostic method for prostate cancer that targets tumor promoting fibroblast-derived exosomes
2016 - 2019 Mechanisms for development of castration resistance by fluctuation of the differentiation in human prostate cancer cells
2015 - 2019 Safety and Clinical Outcomes of Percutaneous Cryoablation for Musculoskeletal Tumors: a Phase-II Clinical Study (UMIN 000009906)
2013 - 2016 A new insight of cell-cell interactions in tumor stroma of prostate cancer

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Papers (82)：

Nicolas Leventoux, Satoru Morimoto, Mitsuru Ishikawa, Shiho Nakamura, Fumiko Ozawa, Reona Kobayashi, Hirotaka Watanabe, Sopak Supakul, Satoshi Okamoto, Zhi Zhou, et al. Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes. Acta neuropathologica. 2024. 147. 1. 84-84
Hiroya Kobayashi, Koji Ueda, Satoru Morimoto, Mitsuru Ishikawa, Nicolas Leventoux, Ryogen Sasaki, Yoshifumi Hirokawa, Yasumasa Kokubo, Hideyuki Okano. Protein profiling of extracellular vesicles from iPSC-derived astrocytes of patients with ALS/PDC in Kii peninsula. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023. 44. 12. 4511-4516
金山和樹, 今井裕, 松田知世, 臼杵恵梨, 広川佳史, 渡邉昌俊. Extrachromosomal DNAは動的調節を介して胃癌での受容体型チロシンキナーゼ発現の腫瘍内不均一性に寄与する(Extrachromosomal DNA contributes to intratumoral heterogeneity of RTKs in gastric cancer through dynamic regulation). 日本癌学会総会記事. 2023. 82回. 1004-1004
Chise Matsuda, Kenichiro Ishii, Yasuhisa Nakagawa, Taku Shirai, Takeshi Sasaki, Yoshifumi S Hirokawa, Kazuhiro Iguchi, Masatoshi Watanabe. Fibroblast-derived exosomal microRNA regulates NKX3-1 expression in androgen-sensitive, androgen receptor-dependent prostate cancer cells. Journal of cellular biochemistry. 2023. 124. 8. 1135-1144
Chao Qi, Bert M Verheijen, Yasumasa Kokubo, Yang Shi, Stephan Tetter, Alexey G Murzin, Asa Nakahara, Satoru Morimoto, Marc Vermulst, Ryogen Sasaki, et al. Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold. bioRxiv : the preprint server for biology. 2023

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MISC (61)：

Kenichiro Ishii, Izumi Matsuoka, Takeshi Sasaki, Manabu Kato, Kohei Nishikawa, Hideki Kanda, Yoshifumi Hirokawa, Kazuhiro Iguchi, Kiminobu Arima, Masatoshi Watanabe, et al. Loss of fibroblasts-dependent androgen receptor activation in prostate cancer cells develops castration-resistant prostate cancer. CANCER RESEARCH. 2019. 79. 13
石井健一朗, 臼杵恵梨, 広川佳史, 金山和樹, 松田知世, 内田克典, 杉村芳樹, 渡邉昌俊. 抗線維化薬ピルフェニドンによる癌細胞増殖抑制機構の解析(Pirfenidone, an anti-fibrotic agent, inhibits cell growth of human cancer cells). 日本病理学会会誌. 2018. 107. 1. 299-299
内田克典, 森尾邦正, 西井正彦, 芝原拓児, 大西毅尚, 林昭伸, 広川佳史, 矢花正, 渡邉昌俊. 筋層非浸潤性膀胱癌の再発リスク分類作成の試み. 日本病理学会会誌. 2018. 107. 1. 317-317
内田克典, 森尾邦正, 栗山直久, 臼井正信, 伊佐地秀司, 林昭伸, 広川佳史, 渡邉昌俊. The regression and risk grouping of perihilar cholamgiocarcinoma following neoadjuvant therapy(和訳中). 日本病理学会会誌. 2018. 107. 1. 363-363
広川佳史, 石井健一朗, 金山和樹, 林昭伸, 内田克典, 小塚祐司, 今井裕, 福留寿生, 渡邉昌俊. PC-3前立腺がん細胞株におけるHer2、MUC4とシグナル伝達経路. 日本病理学会会誌. 2018. 107. 1. 391-391

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Professional career (1)：

医学博士 (三重大学)

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