Rchr
J-GLOBAL ID：201801009158622713
Update date: Nov. 19, 2024
Iribe Gentaro
イリベ ゲンタロウ | Iribe Gentaro
Affiliation and department：
Job title：
Professor
Research field (2)：
Clinical pharmacy
, Physiology
Research keywords (4)：
mechano-electric coupling
, 心臓力学
, mechano-electric coupling
, cardiac mechanics
Research theme for competitive and other funds (25)：
- 2021 - 2024 新規メカニカル負荷装置の開発を通した次世代メカノメディスンへの挑戦
- 2021 - 2024 Force-Length Relationによる単離ヒト心筋細胞の機能評価
- 2021 - 2024 心筋機械感受性制御におけるROSシグナリングの役割とその心不全治療への展開
- 2020 - 2023 Investigation of NOX4-mediated mechanotransduction in mechanically-induced cardiac failure
- 2017 - 2020 Physiological and pathophysiological role of NOX4 in cardiac mechano-transduction
- 2014 - 2019 Mechanomedicine: Application of mechanobiological engineering to regenerative and reproductive medicine
- 2016 - 2018 Multi-level analysis of ischemic heart disease pathology based on heterogeneity in mechano-electric coupling
- 2014 - 2017 Role of reactive oxygen species in physiology and pathophysiology of cardiac biomechanics
- 2014 - 2015 心疾患治療に向けた革新的次世代メカノ組織工学・再生医療の創生
- 2010 - 2015 Integrative study on arrhythmogenicity associated with adaptive and pathological remodeling of stressed hearts.
- 2011 - 2014 role of mechanosensitive response of organelle in dynamic biomechanics of cardiomyocytes
- 2010 - 2012 Elucidation of Biological Adaptation and Remodeling Mechanisms to Mechanical Stress Based on the Development of Novel Micro-Electro-Mechanical Systems (MEMS) technology
- 2008 - 2010 Role of mechanical load in human myocardial excitation contraction coupling
- 2008 - 2009 単離心筋機械負荷操作を用いた心臓の機械電気相互作用の統合生理研究
- 2007 - 2009 The role of mechanosensor on cardiovascular disease.
- 2005 - 2009 Application of Soft Lithography to Mechanobiology
- 2001 - 2004 Analysis of coronary microcirculation and myocardial crossbridge dynamic using SPring-8 synchrotron facility
- 2002 - 2002 心筋クロスブリッジ動態ナノメカニクスが心臓ポンプ機能に及ぼす影響
- 2001 - 2002 病態モデル小動物における腎糸球体微小循環可視化法の開発と病態生理学的解析
- 2001 - 2001 複合化原子間力顕微鏡を応用した単離心筋細胞骨格化に伴う力学と代謝特性の解析
- 2000 - 2001 EVAUATION OF CROSS-SECTIONAL AREA OF CORONARY ARTERIES BY CONDUCTANCE CATHETER : TOWORD ITS APPLICATION TO PTCA
- 2000 - 2001 SPring8放射光を用いた重元素ステレオ造影による心筋微小血管ダイナミクス解析
- 1998 - 1999 統合生理学的分析法による心臓内カルシウム無駄サイクル数の推定法
- 1998 - 1999 Assessment of the total amount of CAィイD12+ィエD1 handled in the E-C coupling by analyzing postextrasystolic potentiation and OィイD22ィエD2 consumption : Systems approach
- 1997 - 1999 Macro-micro correspondence in mechanoenagetics of failing hearts
Show all
Papers (55)：
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Keiko Kaihara, Hiroaki Kai, Yumiko Chiba, Keiji Naruse, Gentaro Iribe. Stretch-induced reactive oxygen species contribute to the Frank-Starling mechanism. The Journal of Physiology. 2023. 602. 18. 4347-4362
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Sayaka Oda, Kazuhiro Nishiyama, Yuka Furumoto, Yohei Yamaguchi, Akiyuki Nishimura, Xiaokang Tang, Yuri Kato, Takuro Numaga-Tomita, Toshiyuki Kaneko, Supachoke Mangmool, et al. Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through β-adrenoceptors. Nature Communications. 2022. 13. 1
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Yohei Yamaguchi, Masayoshi Nishiyama, Hiroaki Kai, Toshiyuki Kaneko, Keiko Kaihara, Gentaro Iribe, Akira Takai, Keiji Naruse, Masatoshi Morimatsu. High hydrostatic pressure induces slow contraction in mouse cardiomyocytes. Biophysical journal. 2022
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Rémi Peyronnet, Olga Solovyova, Gentaro Iribe, Leonid B. Katsnelson. Editorial: Mechano-Calcium, Mechano-Electric, and Mechano-Metabolic Feedback Loops: Contribution to the Myocardial Contraction in Health and Diseases. Frontiers in Physiology. 2021. 12
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Breanne A. Cameron, Hiroaki Kai, Keiko Kaihara, Gentaro Iribe, T. Alexander Quinn. Ischemia Enhances the Acute Stretch-Induced Increase in Calcium Spark Rate in Ventricular Myocytes. Frontiers in Physiology. 2020. 11
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MISC (50)：
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千葉弓子, 貝原恵子, 入部玄太郎. 心筋の伸展刺激誘発性ROS産生のメカノトランスダクション. 日本生体医工学会大会プログラム・抄録集(Web). 2024. 63rd
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Komatsu Hiroaki, Kotani Yasuhiro, Kaihara Keiko, Naruse Keiji, Kasahara Shingo, Iribe Gentaro. Single cell mechanics of human cardiomyocytes assessed by cellular force-length relationships(タイトル和訳中). The Journal of Physiological Sciences. 2023. 73. Suppl.1. 108-108
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Yamaguchi Yohei, Kaneko Toshiyuki, Iribe Gentaro, Ohya Susumu. Myocardial TRPC6 modulates stretch-induced increase in contractility via Zn2+ mobilization. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 2-B-P-006
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Kaihara Keiko, Naruse Keiji, Iribe Gentaro. マウス心室心筋細胞におけるNOX4-TRPV1相互作用の単一細胞力学に対する役割(Role of NOX4-TRPV1 interaction on single cell mechanics in mouse ventricular cardiomyocytes). The Journal of Physiological Sciences. 2022. 72. Suppl.1. 117-117
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Kaihara Keiko, Naruse Kenji, Iribe Gentaro. NOX4由来のROSが心筋細胞メカニクスに及ぼす影響(Effects of NOX4-induced ROS on single cell mechanics in mouse ventricular cardiomyocytes). The Journal of Physiological Sciences. 2021. 71. Suppl.1. 163-163
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Books (4)：
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Biological, Physical and Technical Basics of Cell Engineering.
Springer 2018
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Cardiac mechano-electric coupling and arrhythmias. 2nd edition
Oxford University Press 2011
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バイオテクノロジーシリーズ 細胞分離・操作技術の最前線
(株)シーエムシー 2008
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細胞分離・操作技術の最前線
シーエムシー出版 2008
Lectures and oral presentations (30)：
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Application of mechanobiological engineering to regenerative and reproductive medicine
(第56回日本生体医工学会大会 2017)
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TRPC3 participates in the angiotensin II type 1 receptor-dependent slow force response to stretch in mouse cardiomyocytes
(7th International Workshop on Cardiac Mechano-Electric Coupling and Arrhythmia 2016)
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TRPC3 participates in the angiotensin II type 1 receptor-dependent slow force response to stretch in mouse cardiomyocytes
(The 45th European Muscle Conference 2016)
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Localization of TRPC3 channels estimated by in-silico and cellular functional experiments
(Experimental and Computational Biomedicine 2016)
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Role of TRPC3 in a Slow Force Response to Stretch on Mice Cardiomyocytes
(第8回アジア・オセアニア生理学会連合(FAOPS)2015年大会 2015)
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Education (1)：
- - 2007 University of Oxford
Professional career (1)：
Work history (5)：
- 2019 - 現在 Asahikawa Medical University Dept. Physiology Professor
- 2016 - 2019 岡山大学医歯薬学総合研究科 准教授
- 2013 - 2016 岡山大学医歯薬学総合研究科 講師
- 2013 - 2016 Senior Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
- 2016 - Associate Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
Committee career (3)：
- 2015 - 日本生体医工学会 代議員
- 2014 - 日本生理学会 評議員
- 2009 - ヨーロッパ心臓病学会(European Society of Cardiology) フェロー(FESC)
Awards (1)：
- 2005 - Sevier Poster Award
Association Membership(s) (6)：
日本生理学会
, ヨーロッパ心臓病学会(European Society of Cardiology)
, 米国生物物理学会(Biophysical Society)
, 日本生体医工学会
, 日本循環制御医学会
, 日本生物物理学会
