Rchr
J-GLOBAL ID：201801010549650272   Update date: Jun. 20, 2024

Nakakido Makoto

Nakakido Makoto
Affiliation and department：
The University of Tokyo

About The University of Tokyo


Job title： Lecturer
Research field  (4)： Biophysics ,  Molecular biology ,  Bacteriology ,  Molecular biochemistry
Research keywords  (6)： Molecular modality ,  Antibacterial agents ,  Thermodynamic analysis ,  Protein-protein interaction ,  Antibody engineering ,  Post-translational modification
Research theme for competitive and other funds  (9)：
  • 2022 - 2025 A群レンサ球菌の金属輸送系を標的とした治療薬剤としての人工抗体の取得
  • 2021 - 2024 脳分子を回収して帰還する「はやぶさ型ナノマシン」の開発
  • 2021 - 2024 Innovative nanotechnology for probing molecular landscapes in the brain
  • 2019 - 2024 生命金属動態の理解と制御のための分子認識素子の開発
  • 2020 - 2023 Elucidation and Control of Local Fractions in Protein Engineering
Show all
Papers (80)：
  • Sae Ito, Ryo Matsunaga, Makoto Nakakido, Daisuke Komura, Hiroto Katoh, Shumpei Ishikawa, Kouhei Tsumoto. High-throughput system for the thermostability analysis of proteins. Protein science : a publication of the Protein Society. 2024. 33. 6. e5029
  • Risa Asano, Miyu Takeuchi, Makoto Nakakido, Sho Ito, Chihiro Aikawa, Takeshi Yokoyama, Akinobu Senoo, Go Ueno, Satoru Nagatoishi, Yoshikazu Tanaka, et al. Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA. Protein science : a publication of the Protein Society. 2024. 33. 6. e5017
  • Risa Asano, Makoto Nakakido, Jorge Fernández Pérez, Tomoko Ise, Jose M.M. Caaveiro, Satoshi Nagata, Kouhei Tsumoto. Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab. Biochemical and Biophysical Research Communications. 2024. 714. 149969-149969
  • Koichi Yamamoto, Satoru Nagatoishi, Makoto Nakakido, Daisuke Kuroda, Kouhei Tsumoto. Functional insights of Tyr37 in framework region 2 directly contributing to the binding affinities and dissociation kinetics in single-domain VHH antibodies. Biochemical and Biophysical Research Communications. 2024
  • Akinobu Senoo, Masato Hoshino, Toshiki Shiomi, Makoto Nakakido, Satoru Nagatoishi, Daisuke Kuroda, Ichiro Nakagawa, Jeremy R H Tame, Jose M M Caaveiro, Kouhei Tsumoto. Structural basis for the recognition of human hemoglobin by the heme-acquisition protein Shr from Streptococcus pyogenes. Scientific reports. 2024. 14. 1. 5374-5374
ｍore...
MISC (33)：
  • 中木戸誠, 小菅啓史, 長門石曉, 福田哲也, 板東泰彦, VEGA Susana, 大沼信一, 津本浩平, 津本浩平. 腫瘍抑制蛋白質PRELPのマルチバレント相互作用を介した機能制御. 日本生化学会大会(Web). 2023. 96th
  • 小菅啓史, 中木戸誠, 中木戸誠, DE VEGA Susana, 長門石曉, 福田哲也, 板東泰彦, 大沼信一, 津本浩平, 津本浩平, et al. 細胞外マトリクスへの局在を介した多重特異性蛋白質PRELPの低親和性相互作用の制御機構の解析. 日本生化学会大会(Web). 2023. 96th
  • KOSUGE Hirofumi, NAKAKIDO Makoto, DE VEGA Susana, NAGATOISHI Satoru, FUKUDA Tetsuya, BANDO Yasuhiko, OHNUMA Shin-ichi, TSUMOTO Kouhei, TSUMOTO Kouhei. Characterization of modulation system of multi-specific interactions of PRELP with intrinsically weak affinity through ECM localization. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
  • KOSUGE Hirofumi, KOSUGE Hirofumi, NAKAKIDO Makoto, NAKAKIDO Makoto, NAGATOISHI Satoru, FUKUDA Tetsuya, BANDO Yasuhiko, OHNUMA Shin-ichi, TSUMOTO Kouhei, TSUMOTO Kouhei. Identification and validation of multi-specific interactions of a tumor suppressor protein PRELP. Program & Abstracts. International Symposium on Tumor Biology in Kanazawa. 2022. 2022 (Web)
  • 天野 晶子, 三條 伸夫, 安楽 泰孝, 中木戸 誠, 松原 悦朗, 永田 哲也, 西田 陽一郎, 荒木 亘, 津本 浩平, 片岡 一則, et al. ナノミセル内包型抗Aβオリゴマー抗体によるアルツハイマー病態改善効果. Dementia Japan. 2021. 35. 4. 660-660
ｍore...
Patents (2)：
  • Robo1に対する親和性を向上させた抗体および高親和性抗体の分子設計方法
  • ROBO1タンパク質に対するダイアボディ型二重特異性抗体
Books (7)：
  • AI・ナノ・量子による超高感度・迅速バイオセンシング
    2021
  • 生命金属ダイナミクス : 生体内における金属の挙動と制御
    エヌ・ティー・エス 2021 ISBN:9784860437060
  • 機器分析ハンドブック
    化学同人 2020 ISBN:9784759820225
  • 細胞表層工学の進展 = Development of cell surface engineering
    シーエムシー出版 2020 ISBN:9784781314969
  • 神経難病と抗体医薬による分子標的治療
    医薬ジャーナル Vol.54, No.7 2018
ｍore...
Education (2)：
  • 2006 - 2011 The University of Tokyo
  • 2002 - 2006 The University of Tokyo The Faculty of Engineering Department of Chemistry and Biotechnology
Professional career (1)：
  • 博士(生命科学) (東京大学)
Work history (6)：
  • 2020/11 - 現在 東京大学工学系研究科バイオエンジニアリング専攻 講師
  • 2017/08 - 2020/10 The University of Tokyo School of Engineering, Department of Bioengineering Assistant professor
  • 2017/01 - 2017/07 The University of Tokyo School of Engineering, Department of Bioengineering Project assistant professor
  • 2016/04 - 2016/12 The University of Tokyo School of Engineering, Department of Bioengineering Project researcher
  • 2013/01 - 2015/12 The University of Chicago Department of medicine Postdoctoral scholar
Show all
Awards (4)：
  • 2019/10 - JB論文賞 日本生化学会
  • 2015/07 - The Japanese Biochemical Society JB prize for publication
  • 2011/03 - 東京大学新領域創成科学研究科メディカルゲノム専攻 Excellent Research Award(博士)
  • 2009/03 - 東京大学新領域創成科学研究科メディカルゲノム専攻 Excellent Research Award(修士)
Association Membership(s) (3)：
PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  日本神経科学学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM