Cao Liqin

Affiliation and department：
Job title： Assistant Professor

Research field (7)： Basic brain sciences , Basic brain sciences , Laboratory animal science , Animals: biochemistry, physiology, behavioral science , Laboratory animal science , Animals: biochemistry, physiology, behavioral science , Genetics

Research theme for competitive and other funds (3)：

2017 - 2020 先天的恐怖誘発機構の解明および精神疾患との関連
2010 - 2013 ミトコンドリアの遺伝的ボトルネック形成機構の解析と疾患との関連
2009 - 2012 Mouse mitochondrial inheritance and dynamics

Papers (14)：

Zhiqiang Wang, Jing Ma, Chika Miyoshi, Yuxin Li, Makito Sato, Yukino Ogawa, Tingting Lou, Chengyuan Ma, Xue Gao, Chiyu Lee, et al. Quantitative phosphoproteomic analysis of the molecular substrates of sleep need. Nature. 2018. 558. 7710. 435-439
Wang, Yibing, Cao, Liqin, Lee, Chia-Ying, Matsuo, Tomohiko, Wu, Kejia, Asher, Greg, Tang, Lijun, Saitoh, Tsuyoshi, Russell, Jamie, Klewe-Nebenius, Daniela, et al. Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors. 2018. Nature communications 9. 1. 2041
Hiroshi Shitara, Liqin Cao, Midori Yamaguchi, Hiromichi Yonekawa, Choji Taya. Establishment of a heteroplasmic mouse strain with interspecific mitochondrial DNA haplotypes and improvement of a PCR-RFLP-based measurement system for estimation of mitochondrial DNA heteroplasmy. TRANSGENIC RESEARCH. 2017. 26. 4. 559-565
Liqin Cao, Satoru Kobayakawa, Atsushi Yoshiki, Kuniya Abe. High Resolution Intravital Imaging of Subcellular Structures of Mouse Abdominal Organs Using a Microstage Device. PLOS ONE. 2012. 7. 3. e33876
Liqin Cao, Hiroshi Shitara, Michihiko Sugimoto, Jun-Ichi Hayashi, Kuniya Abe, Hiromichi Yonekawa. New Evidence Confirms That the Mitochondrial Bottleneck Is Generated without Reduction of Mitochondrial DNA Content in Early Primordial Germ Cells of Mice. PLOS GENETICS. 2009. 5. 12. e1000756

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Books (5)：

睡眠問題の解決に向けた国際統合睡眠医科学研究機構の取り組み
バイオサイエンスとインダストリー 76巻、6号 2018
Advances in Intravital Microscopy - From Basic to Clinical Research chapter 8 Live Imaging of Subcellular Structures and Cellular Processes in Mouse Intraperitoneal Organs
Springer Netherlands 2014
特集:その時ミトコンドリアは動いた(独自の品質管理システムから疾患に迫る)哺乳動物におけるミトコンドリアDNAの遺伝様式: 急調分離とボトルネック効果
細胞工学・学研メディカル秀潤社 2010
特集:ミトコンドリアの遺伝機構とエネルギー代謝制御哺乳類におけるミトコンドリアボトルネック効果
実験医学/羊土社 2008
Special Review: ミトコンドリア遺伝子の同質性とボトルネック効果:通説の崩壊
細胞工学・学研メディカル秀潤社 2007

Lectures and oral presentations (13)：

Sleep phenotyping in the CDKL5 knockout mouse model
(2019 CDKL5 Forum 2019)
Sleep disruptions in CDKL5 knockout mice
(CDKL5 ASIA Workshop 2019 2019)
A forward-genetic approach to identifying molecular drivers of fear/psychiatric disorders
(The 6th Annual IIIS Symposium 2017)
Molecular basis of innate fear: from fear genes to fear/anxiety disorders
(The 5th Annual IIIS Symposium and The 32nd Wako Workshop 2016)
Understanding the molecular basis of fear and the role of emotion in sleep regulation
(The 4th Annual IIIS Symposium 2016)

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Education (1)：

1997 - 2003 Dalhousie University, Canada, Biology Department

Professional career (1)：

Ph.D (Dalhousie University)

Work history (8)：

2014/10 - 現在 University of Tsukuba International Institute for Integrative Sleep Medicine (WPI-IIIS) Assistant Professor
2013/07 - 2014/09 University of Tsukuba International Institute for Integrative Sleep Medicine (WPI-IIIS) Researcher
2012/04 - 2013/06 RIKEN RIKEN Bio Resource Center Researcher
2009/04 - 2012/03 RIKEN RIKEN Bio Resource Center Foreign Postdoctoral Researcher
2006/10 - 2009/03 Japan Biological Informatics Consortium Research Scientist

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Awards (2)：

2010/02 - RIKEN Recognition of excellent research achievements
2009/11 - The 6th Conference ofAsian Society for Mitochondrial Research and Medicine Best Paper Award

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