Research theme for competitive and other funds (9):
2020 - 2023 Elucidation of molecular basis of biosynthesis with the aim of expanding the diversity of natural products
2019 - 2021 Construction of biosynthetic platform based on metabolism logic of actinomycete and elucidation of the function of unknown biosynthetic gene
Islam A. Abdelhakim, Yushi Futamura, Yukihiro Asami, Hideaki Hanaki, Naoko Kito, Sachiko Masuda, Arisa Shibata, Atsuya Muranaka, Hiroyuki Koshino, Ken Shirasu, et al. Expression of Syo_1.56 SARP Regulator Unveils Potent Elasnin Derivatives with Antibacterial Activity. Journal of Natural Products. 2024
Katsuyuki Sakai, Yushi Futamura, Toshihiko Nogawa, Yuzhu Zhao, Hiroyuki Koshino, Hiroyuki Osada, Shunji Takahashi. Production of Kinanthraquinone D with Antimalarial Activity by Heterologous Gene Expression and Biotransformation in Streptomyces lividans TK23. Journal of Natural Products. 2024. 87. 4. 855-860
岡村英治, 佐藤(汐崎)裕美, 奥村英夫, 熊坂崇, 長田裕之, 高橋俊二. Analysis of RevL mutants based on model structure of RevK-RevL complex involved in reveromycin biosynthesis and determination of their interaction regions. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
岡村英治, 佐藤(汐崎)裕美, 奥村英夫, 熊坂崇, 長田裕之, 高橋俊二. Identification of key interacting residues of complex enzymes involved in reveromycin A biosynthesis. 日本放線菌学会大会講演要旨集. 2022. 36th
岡村英治, 佐藤(汐崎)裕美, 奥村英夫, 熊坂崇, 長田裕之, 高橋俊二. Prediction by in sillico analysis and experimental validation of interaction of RevKLM complex for Reveromycin A biosynthesis. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
野川俊彦, 寺井淳高, 新家一男, 池田治生, 高橋俊二, 長田裕之. Structures of new verticilactam derivatives by heterologous expression. 日本農芸化学会大会講演要旨集(Web). 2020. 2020