Miyake Kensuke

ミヤケケンスケ | Miyake Kensuke

Affiliation and department：
Job title： Associate Professor
Homepage URL (2)： https://immune-regulation.org/ , https://immune-regulation.org/index.php?id=27

Research field (3)： Allergies and connective tissue disease , Immunology , Experimental pathology

Research theme for competitive and other funds (3)：

Papers (52)：

三宅健介, 伊藤潤哉, 烏山一. 【ヒト疾患と免疫細胞サブセット解像度をあげて見えてきた病態を規定する疾患のキープレーヤーと治療戦略】(第1章)自然免疫系皮膚アレルギー炎症における好塩基球の役割. 実験医学. 2024. 42. 12. 1812-1819
三宅健介, 伊藤潤哉, 烏山一. アトピー性皮膚炎病態における好塩基球の役割. 臨床免疫・アレルギー科. 2024. 82. 2. 154-161
Miyake K, Ito J, Karasuyama H. Novel insights into the ontogeny of basophils. Frontiers in allergy. 2024. 5. 1402841
伊藤潤哉, 三宅健介, 烏山一. 1細胞RNAシーケンス解析による好塩基球分化機構の解明. 臨床免疫・アレルギー科. 2024. 81. 5. 497-503
Tchen J, Simon Q, Chapart L, Thaminy MK, Vibhushan S, Saveanu L, Lamri Y, Saidoune F, Pacreau E, Pellefigues C, et al. PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus. Nature communications. 2024. 15. 1. 3389

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MISC (2)：

柴田翔, 三宅健介, 立石知也, 烏山一, 宮崎泰成. 好酸球と好塩基球の活性化メカニズムマウス,ヒトにおいて好中球エラスターゼは好塩基球からのIL-4分泌を促進する. アレルギー. 2021. 70. 6-7. 799-799
高橋和総, 三宅健介, 須田真実, 大橋健一, 烏山一. 結膜炎・皮膚炎・免疫療法・寄生虫好塩基球由来IL-4はマクロファージのCCL24産生を促し,好酸球浸潤を誘導する. アレルギー. 2021. 70. 6-7. 821-821

Books (2)：

Global Atlas of Asthma, 2nd Edition
European Academy of Allergy and Clinical Immunology 2021
The Immune System, 4th edition
2016 ISBN:9784895928649

Lectures and oral presentations (68)：

アトピー性皮膚炎における好塩基球の役割
(第123回日本皮膚科学会総会)
Basophils promote the differentiation of pro-resolving macrophages with high efferocytic ability from classical monocytes in skin allergy
(11th European mast cell and basophil research network meeting (EMBRN2024))
Classical monocyte-derived macrophages display high efferocytic ability and contribute to the resolution of basophil-dependent skin allergic inflammation
(The 52nd Annual Meeting of the Japanese Society for Immunology 2024)
FoxO1 regulates the number of basophils in the peripheral tissues and basophil-dependent allergic inflammation
(The 52nd Annual Meeting of the Japanese Society for Immunology 2024)
Pro-Resolving Roles for Basophils and Monocyte-Derived Macrophages in IgE-Mediated Skin Allergy
(2024 Food Allergy Conference GRC 2024)

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Education (2)：

2014 - 2017 Tokyo Medical and Dental University Graduate School, Division of Medicine
2008 - 2014 Tokyo Medical and Dental University Faculty of Medicine

Professional career (2)：

Work history (4)：

2024/04 - 現在 Tokyo Medical and Dental University Institute of Research Associate Professor (tenure track)
2020/04 - 2024/03 Tokyo Medical and Dental University Institute of Research Project Assistant Professor
2017/04 - 2020/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Immune Regulation Project Assistant Professor
2014/04 - 2017/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Immune Regulation Graduate Student

Committee career (1)：

Awards (14)：

2022/03 - 大山健康財団第48回大山健康財団学術研究助成金 Nippostrongylus brasiliensis再感染時の未熟好塩基球浸潤機構の解明
2022/02 - 公益財団法人内藤記念科学振興財団 2021年度内藤記念次世代育成支援研究助成金アレルギー炎症抑制型M2マクロファージの分化・誘導機構の解明
2021/12 - 公益財団法人上原記念生命科学財団 2021年度上原記念生命科学財団研究奨励金炎症後期M2マクロファージの皮膚アレルギー抑制機構
2021/11 - 公益財団法人武田科学振興財団武田科学振興財団 2021年度医学系研究助成(基礎)
2021/11 - 公益財団法人かなえ医薬振興財団第50回かなえ医薬振興財団研究助成金好塩基球により誘導されたM2マクロファージによる皮膚アレルギー炎症抑制機構の解明

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Association Membership(s) (3)：

The Molecular Biology Society of Japan , 日本免疫学会 , 日本アレルギー学会

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