Research keywords (3):
血管内皮細胞
, 血液脳関門(BBB)
, iPS細胞
Research theme for competitive and other funds (5):
2021 - 2023 ヒトiPS細胞からP-糖タンパク質を高発現する脳血管内皮細胞の作製
2018 - 2021 マスト細胞分化におけるGfi1の役割
2012 - 2012 Differentiation of plasmacytoid dendritic cells from iPS cells and its application for Vaccine development
2011 - 2012 Elucidation of the mechanism of VA-RNA-induced innate immune response
2007 - 2009 遺伝子治療薬の生体内投与後の毒性発現機構解析
Papers (70):
Tomoko Yamaguchi, Daiki Sako, Toshiki Kurosawa, Misae Nishijima, Ayaka Miyano, Yoshiyuki Kubo, Sumio Ohtsuki, Kenji Kawabata, Yoshiharu Deguchi. Development and Functional Evaluation of MDR1-Expressing Microvascular Endothelial-Like Cells Derived from Human iPS Cells as an In Vitro Blood-Brain Barrier Model. Journal of pharmaceutical sciences. 2023
Hongyan Zhang, Tomoko Yamaguchi, Kenji Kawabata. The maturation of iPS cell-derived brain microvascular endothelial cells by inducible-SOX18 expression. Fluids and barriers of the CNS. 2023. 20. 1. 10-10
Hiromi Nakao, Tomoko Yamaguchi, Kenji Kawabata, Katsuaki Higashi, Motohiro Nonaka, Makoto Tsuiji, Yuko Nagai, Hidenao Toyoda, Yoshiki Yamaguchi, Nobuko Kawasaki, et al. Characterization of novel antibodies that recognize sialylated keratan sulfate and lacto-N-fucopentaose I on human induced pluripotent cells: comparison with existing antibodies. Glycobiology. 2022
黒澤俊樹, 手賀悠真, 山口朋子, 川端健二, 望月達貴, 井上勝央, 楠原洋之, 出口芳春. Analysis of 6-mercaptopurine transport mechanism across blood-brain barrier model derived from human iPS cells. 日本薬剤学会年会講演要旨集(CD-ROM). 2020. 35th
Blood brain barrier disruption in cerebral ischemia: from the viewpoint of in vitro model analysis.
Avid Science. 2017
Selective differentiation into hematopoietic and cardiac cells from pluripotent stem cells based on the expression of cell surface markers
Springer Protocol Methods in Molecular Biology ES Cells: Methods and Protocols- 2nd Edition 2016