Research field (5):
Immunology
, Oral medicine (pathology)
, Conservative dentistry and endodontics
, Allergies and connective tissue disease
, Laboratory animal science
Research theme for competitive and other funds (14):
2018 - 2021 Dynamics of immune regulation in oral chronic inflammation and cancer, and their connection to systemic immunity
2017 - 2020 Role of VISTA in periodontitis
2014 - 2017 Analysis of characteristic immune regulation in the oral cavity
2014 - 2017 Roles of interleukin-33 in gingival Inflammation
2014 - 2017 Does Advanced Glycation End products (AGEs) is useful for risk management of implant treatment ?
2013 - 2016 Analyses for persistent inflammation in the skin and oral mucosa
2012 - 2014 Roles of interleukin-33 in gingival inflammation
2011 - 2014 Regulatory mechanisms in oral tissue-specific immune responses and tolerance
2010 - 2012 Involvement of Oral Mucosal Immune System in Sublingual Immunotherapy
2010 - 2011 T細胞に依存しない新たな補助シグナル分子機能の解明
2010 - 2011 The analysis of IL-33 inducible Th17 cells in allergic airway inflammation
2006 - 2007 チロシンキナーゼTxkによるマスト細胞のTh1/Th2応答の制御機構
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Papers (48):
Takafumi Numata, Masashi Ikutani, Ken Arae, Tatsukuni Ohno, Koki Okada, Takayuki Yoshimoto, Katsuko Sudo, Hajime Suto, Ko Okumura, Hirohisa Saito, et al. IL-10 promotes Th17 cell differentiation by enhancing STAT1-dependent IL-6 production via IgE-stimulated mast cells. Scientific reports. 2024. 14. 1. 26706-26706
Yuka Sendai, Kazuyoshi Takeda, Keisuke Ohta, Susumu Nakae, Kyotaro Koshika, Kei Kitamura, Makoto Higuchi, Tatsuya Ichinohe, Toshifumi Azuma, Ko Okumura, et al. Ro5-4864, a translocator protein ligand, regulates T cell-mediated inflammatory responses in skin. International immunology. 2024
Satoshi Hanzawa, Makiko Sugiura, Susumu Nakae, Masahiro Masuo, Hideaki Morita, Kenji Matsumoto, Kazuyoshi Takeda, Ko Okumura, Masataka Nakamura, Tatsukuni Ohno, et al. The Prostaglandin D2 Receptor CRTH2 Contributes to Airway Hyperresponsiveness during Airway Inflammation Induced by Sensitization without an Adjuvant in Mice. International archives of allergy and immunology. 2024. 1-9
Takayuki Nishijima, Kentaro Okuyama, Shinsuke Shibata, Hiroo Kimura, Munehisa Shinozaki, Takehito Ouchi, Yo Mabuchi, Tatsukuni Ohno, Junpei Nakayama, Manabu Hayatsu, et al. Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury. Inflammation and regeneration. 2024. 44. 1. 6-6
Yumie Takagi, Katsuko Sudo, Sachiko Yamaguchi, Shuzo Urata, Tatsukuni Ohno, Sachiko Hirose, Kiyoshi Matsumoto, Takashi Kuramoto, Tadao Serikawa, Jiro Yasuda, et al. Characterization of novel, severely immunodeficient PrkdcΔex57/Δex57 mice. Biochemical and biophysical research communications. 2023. 678. 193-199