Murata Kazumoto

Affiliation and department：
Job title：教授

Research field (1)： Virology

Research theme for competitive and other funds (13)：

2022 - 2025 免疫賦活およびウイルス宿主免疫抑制機構の抑制によるB型肝炎治療の開発
2017 - 2020 Basic study for HBV clearance using cytokines induced by nucleotide analogues
2014 - 2017 Factors for favorable acquirement of anti-HBsAb by HBV vaccination in healthy adults
2013 - 2016 The mechanism of mitochondrial injury and iron overload induced hepatocarcinogenesis in the post hepatic virus.
2011 - 2014 Response and specific function of IFN-lambda3 against infectious diseases

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Papers (217)：

Masaharu Takahashi, Tsutomu Nishizawa, Akira Nishizono, Manri Kawakami, Yukihiro Sato, Kazunori Kawakami, Masahiko Irokawa, Tomoko Tamaru, Shinichi Miyazaki, Mizuho Shimada, et al. Recent decline in hepatitis E virus prevalence among wild boars in Japan: Probably due to countermeasures implemented in response to outbreaks of classical swine fever virus infection. Virus research. 2024. 348. 199438-199438
Shigeo Nagashima, Putu Prathiwi Primadharsini, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform. JOURNAL OF VIROLOGY. 2023
Masaharu Takahashi, Satoshi Kunita, Tsutomu Nishizawa, Hiroshi Ohnishi, Putu Prathiwi Primadharsini, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto. Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 2021. VIRUSES-BASEL. 2023. 15. 7
Kazumoto Murata, Masashi Mizokami. Possible biological mechanisms of entecavir versus tenofovir disoproxil fumarate on reducing the risk of hepatocellular carcinoma. Journal of gastroenterology and hepatology. 2023. 38. 5. 683-691
Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. VIRUSES-BASEL. 2023. 15. 4

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MISC (35)：

須藤大輔, 吉田昌, 大竹孝明, 一石英一郎, 佐藤貴一, 村田一素, 鈴木裕, 高後裕. Effect of vonoprazan on Clinical Course of endoscopic submucosal dissection in the patients with gastric tumors. 潰瘍. 2020. 47
村田一素, 前仲勝実, 溝上雅史. B型肝炎治療 2018 核酸アナログ製剤によるIFN-λ誘導とそれを標的としたB型肝炎治療薬の探索. Mebio. 2018. 35. 1. 80-87-87
Nao Nishida, Masaya Sugiyama, Hiromi Sawai, Sohji Nishina, Aiko Sakai, Keisuke Kakisaka, Keisuke Hino, Ryo Sumazaki, Yasuhiro Takikawa, Kazumoto Murata, et al. HLA-DRB1-DQB1 haplotypes and BTNL2 gene associate with response to a hepatitis B vaccine. HEPATOLOGY. 2017. 66. 796A-797A
Naohiko Masaki, Masaaki Korenaga, Mikio Yanase, Yuichi Nozaki, Shintaro Mikami, Yoshihiko Aoki, Masatoshi Imamura, Kazumoto Murata, Tatsuya Kanto, Masashi Mizokami. Effects of interferon-free treatment on serum cholesterol levels are different between the two sofosbuvir-based regimens in chronic HCV-infected patients. HEPATOLOGY. 2016. 64. 981A-981A
Kazumoto Murata, Akihiro Matsumoto, Masaya Sugiyama, Eiji Tanaka, Taisuke Inoue, Minoru Sakamoto, Nobuyuki Enomoto, Masao Honda, Shuichi Kaneko, Hiroyuki Gatanaga, et al. Induction of IFN-lambda 3 as an Additional Effect of Nucleotide, Not Nucleoside, Analogs: A New Potential Target for Hepatitis B Virus Infection. HEPATOLOGY. 2016. 64. 306A-306A

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Education (1)：

- 1988 Jichi Medical University Faculty of Medicine

Work history (1)：

2020/04 - 現在 Jichi Medical University Division of Virology, Department of Infection and Immunity Professor

Association Membership(s) (5)：

American Association for the Study of Liver Diseases , 日本消化器内視鏡学会 , 日本内科学会 , 日本消化器病学会 , 日本肝臓学会

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