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J-GLOBAL ID:201801011942670567   Update date: Jul. 15, 2024

Hiroshi Kawaide

Hiroshi Kawaide
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Affiliation and department:
Job title: Professor
Other affiliations (2):
Research field  (1): Bioorganic chemistry
Research keywords  (1): Natural Product Chemistry, Isoprenoid, Biosynthesis
Research theme for competitive and other funds  (26):
  • 2019 - 2022 Biosynthetic enzyme engineering and synthetic biochemical approaches to terpene precision enzyme synthesis
  • 2018 - 2021 The regulatory mechanism of endogenous gibberellin-like substances in a moss
  • 2017 - 2017 進化過程に隠されたジベレリン起源物質の構造解明
  • 2015 - 2017 生合成力を活用した複雑精緻な構造を有する生理活性ジテルペノイドの創製
  • 2016 - 2016 進化過程に隠されたジベレリン起源物質の構造解明
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Papers (108):
  • Tomonobu Toyomasu, So Oshikawa, Ayaka Naoe, Tomoka Moriya, Yuto Hasegawa, Momoko Nakasato, Yuga Ogawa, Hiroki Wakabayashi, Akira Itoh, Yuri Takeda-Kimura, et al. Gibberellin-biosynthetic ent-kaurene synthases in higher plants do not require their non-catalytic domains for the catalysis. Biochemical Journal. 2024
  • Sho Miyazaki, Hiroshi Kawaide, Masatoshi Nakajima. Inactivation Pathway of Diterpenoid Regulator in the Moss Physcomitrium patens. Journal of Plant Growth Regulation. 2024
  • Takeru Shimada, Shiho Minato, Yuto Hasegawa, Koji Miyamoto, Yasumasa Minato, Matthew R Shenton, Kazunori Okada, Hiroshi Kawaide, Tomonobu Toyomasu. Characterization of diterpene synthase genes in Brachypodium distachyon, a monocotyledonous model plant, provides evolutionary insight into their multiple homologs in cereals. Bioscience, biotechnology, and biochemistry. 2023
  • Rui Sun, Maiko Okabe, Sho Miyazaki, Toshiaki Ishida, Kiyoshi Mashiguchi, Keisuke Inoue, Yoshihiro Yoshitake, Shohei Yamaoka, Ryuichi Nishihama, Hiroshi Kawaide, et al. Biosynthesis of gibberellin-related compounds modulates far-red light responses in the liverwort Marchantia polymorpha. The Plant Cell. 2023. 35. 11. 4111-4132
  • Tetsuya Kawakami, Sho Miyazaki, Hiroshi Kawaide. Molecular characterization of a moss isoprene synthase provides insight into its evolution. FEBS Letters. 2023. 597. 16. 2133-2142
more...
MISC (32):
  • 岡田憲典, 川出洋, MAO Lingfeng, QIU Jie, YE Chuyu, FAN Longjiang, 宮本皓司, 山根久和, 林謙一郎, 野尻秀昭. 下等植物ではじめて見いだされた蘚類ハイゴケの生合成遺伝子クラスター. イソプレノイド研究会例会講演要旨集. 2019. 29th
  • Shimane Manami, Natsume Masahiro, Nozaki Hiroshi, Hayashi Ken-ichiro, Kawaide Hiroshi. 14. Evolution in substrate specificity of ent-kaurene synthases for gibberellin biosynthesis. 2014. 49. 32-32
  • Kimura Honoka, Miyazaki Sho, Shimane Manami, Kainuma Ryosuke, Ando Tomoko, Natsume Masahiro, Hayashi Ken-ichiro, Nozaki Hiroshi, Okada Kazunori, Kawaide Hiroshi. 49. Diterpene cyclases in the momilactones-producing moss Hypnum plumaeforme. 2014. 49. 67-67
  • Yang Che-Dong, Miyazaki Sho, Park Seung-Hyun, Otani Masato, Kawaide Hiroshi, Hayashi Ken-ichiro, Asami Tadao, Nakajima Masatoshi. 18. Screening of chemicals that affect protonemal differentiation of Physcomitrella patens. 2014. 49. 36-36
  • Miyazaki Sho, Park Seung-Hyun, Kawaide Hiroshi, Hayashi Ken-ichiro, Asami Tadao, Nakajima Masatoshi. 17. Purification and identification of endogenous metabolites from ent-kaurenoic acid that promote protonemal differentiation of Physcomitrella patens. 2014. 49. 35-35
more...
Books (1):
  • Assays of Protonemal Growth Responses in <I>Physcomitrella patens</I> under Blue- and Red-light Stimuli <I>in Methods in Molecular Biology</I> (Edited by Yamamoto, K.)
    Springer Science + Buisiness Media, LLC, New York 2019
Lectures and oral presentations  (29):
  • 陸上植物における生理活性ジテルペノイドの生合成にみられる機能進化
    (公益社団法人 日本農芸化学会2018年度大会シンポジウム「4SY25 化学で進化・多様性を考える」 2018)
  • 生合成酵素カクテルを用いた標識テルペノイド合成と環化反応機構解析への応用
    (日本農芸化学会2016年度大会シンポジウム「パスウェイエンジニアリングによる機能性テルペン生産研究の新展開」 2016)
  • 陸上生物界でみられる植物ホルモン・ジベレリンの生合成と機能に関する進化論
    (東北大学先端農学セミナー 2016)
  • Biosynthesis and physiological function of a moss-specific diterpneoid hormone
    (Pacifichem2015 2015)
  • 生合成酵素を用いた完全13C標識化テルペノイドの合成と多次元NMRで解析する化学構造と環化反応機構
    (理研NMR天然物シンポジウム 2015)
more...
Education (3):
  • - 1995 Iwate University Graduate School, Division of Agricltural Sciences
  • - 1990 Tokyo University of Agriculture and Technology Graduate School, Division of Agriculture
  • - 1988 Yamagata University Faculty of Agriculture 農芸化学科
Professional career (2):
  • 農学修士 (東京農工大学)
  • 博士(農学) (岩手大学)
Work history (1):
  • Tokyo University of Agriculture and Technology
Committee career (5):
  • 2018/09 - 現在 公益社団法人 日本農芸化学会 代議員(関東支部)
  • 2016/10 - 現在 一般社団法人 植物化学調節学会 学会賞授賞選考委員
  • 2015/03 - 2017/02 公益社団法人 日本農芸化学会 欧文誌編集委員
  • 2005/04 - 2009/03 社団法人 日本農芸化学会 関東支部代議員
  • 2003/04 - 2004/03 社団法人 日本農芸化学会 関東支部幹事補佐
Awards (15):
  • 2023/08 - 日本農芸化学会関東支部 日本農芸化学会関東支部大会 優秀発表賞(共同受賞) 蘚類ハイゴケ(Calohypnum plumiforme)由来のイソプレン合成酵素の同定
  • 2023/08 - 日本蘚苔類学会第52回山形県西川大会 優秀発表賞 (共同受賞) ジテルペン合成酵素から派生した蘚類イソプレン合成酵素の探索
  • 2019/03 - Japan Society for Bioscience, Biotechnology, and Agrochemistry The Excellent Paper Award Published in Bioscience, Biotechnology, & Biochemistry Biosynthetic study of conidiation-inducing factor conidiogenone: Heterologous production and cyclization mechanism of a key bifunctional diterpene synthase.
  • 2018/03/15 - 公益社団法人 日本農芸化学会 日本農芸化学会BBB論文賞
  • 2017/10/30 - Tokyo University of Agriculture and Technology Top Researcher Award Impact factor値部門
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Association Membership(s) (2):
Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  The Japanese Society for Chemical Regulation of Plants
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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