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J-GLOBAL ID：201801012210962863 Update date: Sep. 14, 2024

Nagano Makoto

ナガノマコト | Nagano Makoto

Affiliation and department：
Other affiliations (1)：

Tokyo University of Science Faculty of Advanced Engineering Department of Biological Science and Technology

Research field (3)： Cell biology , Virology , Tumor biology

Research theme for competitive and other funds (6)：

2021 - 2024 トランスゴルジネットワーク上で制御される新規なエンドソーム形成機構の解明
2013 - 2016 Mechanism of tumor adaptation to the three-dimensional adhesion environment
2012 - 2015 ZF21-FAK軸が制御するリン酸化タンパク質の網羅的同定とその定量的解析
2010 - 2014 Study of MT1-MMP in cancer
2011 - 2013 Development of the experimentalmethod to inhibitthe tumor invasion by targeting a cellmigration factor, ZF21 protein

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Papers (33)：

Makoto Nagano, Hiroki Shimamura, Junko Y. Toshima, Jiro Toshima. Requirement of Rab5 GTPase during heat stress-induced endocytosis in yeast. Journal of Biological Chemistry. 2024. 300(8). 107553. 1-13
Makoto Nagano, Kaito Aoshima, Hiroki Shimamura, Daria Elisabeth Siekhaus, Junko Y Toshima, Jiro Toshima. Distinct role of TGN-resident clathrin adaptors for Vps21p activation in the TGN-endosome trafficking pathway. Journal of Cell Science. 2023. 136. 17. 1-15
Junko Y Toshima, Ayana Tsukahara, Makoto Nagano, Takuro Tojima, Daria E Siekhaus, Akihiko Nakano, Jiro Toshima. The yeast endocytic early/sorting compartment exists as an independent sub-compartment within the trans-Golgi network. eLife. 2023. 12. e84850. 1-27
Ryutaro Kashikuma, Makoto Nagano, Hiroki Shimamura, Kouya Nukaga, Ikumi Katsumata, Junko Y Toshima, Jiro Toshima. Role of phosphatidylserine in the localization of cell surface membrane proteins in yeast. Cell structure and function. 2023. 48. 1. 19-30
Mariko Enshoji, Yoshiko Miyano, Nao Yoshida, Makoto Nagano, Minami Watanabe, Mayumi Kunihiro, Daria E Siekhaus, Junko Y Toshima, Jiro Toshima. Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway. The Journal of Cell Biology. 2022. 221. 10

MISC (4)：

First person - Makoto Nagano. Journal of Cell Science. 2023. 136. 17
長野真. がん浸潤促進分子ZF21の制御機構の解析. 上原記念生命科学財団研究報告集 27 1-6, 2013. 2013
Nishida Chiemi, Kusubata Kaori, Tashiro Yoshihiko, Ismael Gritli, Sato Aki, Koizumi Makiko, Morita Yohei, Nagano Makoto, Sakamoto Takeharu, Koshikawa Naohiko, et al. MT1-MMPはHIF介在性サイトカイン遺伝子転写調節により造血において重要な役割を果たす(MT1MMP plays a critical role in hematopoiesis by regulating HIF-mediated cytokine gene transcription). 臨床血液. 2012. 53. 9. 1104-1104
長野真. 進化するFRETテクノロジー. ファルマシア. 2011. 47. 6. 534-535

Books (3)：

Plasma Membrane Shaping 1st Edition, Part 2-14: Membrane shaping for clathrin-coated pits and endocytosis
ELSEVIER 2023 ISBN:9780323899116
メンブレントラフィック第14章酵母を用いたメンブレントラフィック研究
化学同人 2016 ISBN:9784759817232
がん生物学イラストレイテッド第5章-1 細胞運動と浸潤
羊土社 2011 ISBN:9784758120210

Lectures and oral presentations (127)：

塩基性両親媒性薬剤の細胞内小胞輸送経路に与える影響
(第93回日本生化学会大会 2020)
出芽酵母におけるゴルジ局在Rab11およびPI4キナーゼを介したRab5局在エンドソーム形成機構
(第93回日本生化学会大会 2020)
出芽酵母Rab6ホモログYpt6pのエンドサイトーシスーリサイクリング経路における役割
(第93回日本生化学会大会 2020)
ゴルジ体における糖鎖修飾抑制のエンドサイトーシスに与える影響
(第93回日本生化学会大会 2020)
ゴルジ体PI4キナーゼPik1pによるポストゴルジ体輸送経路を介したエンドサイトーシス経路の制御
(第93回日本生化学会大会 2020)

Education (4)：

2003 - 2008 The University of Tokyo Graduate School of Medicine Pathology
- 2008 The University of Tokyo Graduate School of Medicine Pathology
2001 - 2003 Gifu Pharmaceautical University
1997 - 2001 Gifu Pharmaceutical University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Professional career (1)：

Work history (9)：

2023/04 - 現在 Tokyo University of Science Faculty of Advanced Engineering Department of Biological Science and Technology
2023/04 - 現在 National Institute of Infectious Diseases
2021/04 - 2023/03 Tokyo University of Science Faculty of Advanced Engineering Department of Biological Science and Technology
2017/04 - 2021/03 Tokyo University of Science Faculty of Industrial Science and Technology
2015/04 - 2017/03 Tokyo University of Science Faculty of Industrial Science and Technology

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