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J-GLOBAL ID：201801012237154637 Update date: Mar. 12, 2025

MAEDA Mizuo

マエダミズオ | MAEDA Mizuo

Affiliation and department：
Job title： Assistant Executive Director
Homepage URL (1)： http://www2.riken.jp/lab-www/bioengineering/

Research field (6)： Nano/micro-systems , Nanobioscience , Biomaterials , Biomedical engineering , Analytical chemistry , Polymer chemistry

Research theme for competitive and other funds (43)：

2017 - 2020 Highly-sensitive molecular diagnosis using DNA-carrying nanoparticles with amplification reactions
2016 - 2018 Development of a microchip for capture and disruption of extracellular vesicles toward cancer point-of-care diagnosis
2013 - 2018 Creation of Biomaterials Endowed with Unique Properties of DNA Soft-Interfaces
2008 - 2014 Molecular Soft-Interface Science
2008 - 2013 Molecular Soft-Interface Science

2008 - 2012 Elucidation and application of sequence-specific phenomena of DNA-grafted nanoparticles

2008 - 2011 Highly quantitative gene analysis based on affinity capillary electrophoresis using DNA conjugates

2003 - 2007 Development of deep UV light emitting devices using nano-technology and the application

2003 - 2006 Molecular Design of DNA Conjugate and its Applications to Biosensing

2002 - 2003 DNA-高分子複合化デバイスを用いた遺伝子変異検出用マイクロチップの開発

2001 - 2003 Development of Nanomedicine for the Treatment of Cardiovascular Diseases

2001 - 2002 情報応答性DNA複合体を用いる遺伝子情報制御システム

2000 - 2002 Separation of Oligodeoxyribonucleotides Having Single-base Mutation by Affinity Capillary Electrophoresis Using a DNA- polyacrylamide Conjugate

2000 - 2002 A Polymer Micelle Responding to the Single Nucleotide Mutation

2001 - 2001 DNAコンジュゲート・ナノデバイスによるバイオチップの超機能化

2000 - 2000 DNAコンジュゲートを用いるトリプルターゲッティングシステムの開発

1999 - 2000 刺激応答性DNA複合体を用いる遺伝子情報制御システム

1999 - 1999 DNAポリマーミセルを利用する新規ターゲティングシステムの構築

1998 - 1999 光反応性レドック分子による遺伝子のマルチラベル化と超高感度電子計測

1998 - 1998 DNAナノ組織体の設計・構築と機能発現

1997 - 1998 DNAコンジュゲートによるワンポット・アフィニティー分離

1997 - 1998 Development of Bioaffinity Sensor for DNA Mutation Assay

1995 - 1998 Novel Molecular Imprinting by Latex Polymerization-Basic Research for the Structure of Resin Surface-

1997 - 1997 生体基盤材料の開発

1997 - 1997 DNAナノ組織体の設計・構築と機能発現

1996 - 1997 DNAビニルグラフト法による遺伝子の多点標識と超高感度分析

1996 - 1997 DNA Biosensors for Medical Diagnosis

1996 - 1996 DNAネットワーク組織体の構築と新機能発現

1996 - 1996 界面鋳型形成法による機能性官能基の空間分布制御

1996 - 1996 核酸-希土類金属-有機配位子三元錯体の分子論的研究

1995 - 1996 Development of Separation Material for Saccharide on the Basis of Surface Imprinting Procedure

1994 - 1996 Development of Novel Metal Ion Selective Ion-exchange Resin Based on Surface Template Polymerization

1995 - 1995 核酸-希土類金属-有機配位子三元錯体の分子論的研究

1995 - 1995 DNA構造体を反応場とする電極-溶液界面の電子移動反応とその制御

1994 - 1995 Preparation of Highly-Selective Metal Adsorbents by Surface Imprinting Method

1994 - 1994 核酸-希土類金属-有機配位子三元錯体の分子論的研究

1994 - 1994 DNA構造体を反応場とする電極-溶液界面の電子移動反応とその制御

1993 - 1994 Development of Biosensor Comprising DNA as Affinity Ligand

1992 - 1992 都市人工空間における健康影響サーベイランスシステム

1991 - 1991 都市人工空間における健康影響サ-ベイランスシステム

1990 - 1991 Multiphase Intelligent Materials for Biomimetic Sensors

1990 - 1990 複合系の構造化学的アプロ-チ

1990 - 1990 都市人工空間における健康影響サ-ベイランスシステム

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Papers (442)：

Nanami Fukuzumi, Gen Hirao, Atsushi Ogawa, Tsuyoshi Asahi, Mizuo Maeda, Tamotsu Zako. Density and structure of DNA immobilised on gold nanoparticles affect sensitivity in nucleic acid detection. Scientific Reports. 2025. 15. 1
Yuki Tanaka, Gen Hirao, Nanami Fukuzumi, Tsuyoshi Asahi, Mizuo Maeda, Atsushi Ogawa, Tamotsu Zako. Effect of DNA Density on Nucleic Acid Detection Using Cross-Linking Aggregation of DNA-Modified Gold Nanoparticles. Langmuir. 2025
Nanami Fukuzumi, Takako Nakagawa, Gen Hirao, Atsushi Ogawa, Mizuo Maeda, Tsuyoshi Asahi, Tamotsu Zako. Detection of C-reactive protein using single cluster analysis of gold nanoparticle aggregates using dark-field microscope equipped with smartphone. Sensors & Diagnostics. 2024
Gen Hirao, Nanami Fukuzumi, Atsushi Ogawa, Tsuyoshi Asahi, Maeda Mizuo, Tamotsu Zako. Effect of DNA density immobilized on gold nanoparticles on nucleic acid detection. RSC Advances. 2023. 13. 44. 30690-30695
Luyang Wang, Zhiyu He, Qianyuan Chen, Guoqing Wang, Xingguo Liang, Tohru Takarada, Mizuo Maeda. Refreshing DNA-Based Nanoprobes by Alcohol for Heavy Metal Detection: Toward Sustainable Sensing Nanomaterials. ACS Sustainable Chemistry & Engineering. 2023. 11. 9. 3611-3620

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MISC (1,046)：

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Patents (59)：

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Books (4)：

バイオマテリアルの基礎
日本医学館 2010
ソフトマター分子設計・キャラクタリゼーションから機能性材料まで
丸善 2009 ISBN:4621081691
バイオ材料の基礎 (シリーズ現代工学入門)
岩波書店 2005 ISBN:4000069381
岩波講座現代工学の基礎〈3〉コンピュータシステムの基礎《情報系IV》・バイオ材料の基礎《材料系VIII》
岩波書店 2000 ISBN:4000109839

Education (3)：

1978 - 1983 The University of Tokyo The Graduate School of Engineering
1976 - 1978 The University of Tokyo The Faculty of Engineering
1974 - 1976 The University of Tokyo College of Arts and Sciences

Professional career (1)：

工学博士 (東京大学)

Work history (10)：

2024/04 - 現在国立研究開発法人理化学研究所理事補佐
2021/04 - 現在国立研究開発法人理化学研究所開拓研究本部本部長室長
2021/04 - 2022/03 RIKEN Deputy Executive Director (Research Policy Advisor)
2006/04 - 2022/03 The University of Tokyo Graduate School of Frontier Sciences
2016/04 - 2021/03 Shinshu University Graduate School of Medicine, Science and Technology

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Committee career (6)：

2020/05 - 2022/05 高分子学会副会長
2016/04 - 2018/03 日本バイオマテリアル学会監事
2015/04 - 2017/03 日本分析化学会監事
2002/04 - 2016/03 日本バイオマテリアル学会理事
2013/04 - 2015/03 日本分析化学会副会長

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Awards (7)：

2023/05 - 高分子学会高分子科学功績賞 DNAコンジュゲート高分子の開発と応用展開
2021/11 - 日本バイオマテリアル学会日本バイオマテリアル科学功績賞
2014/09 - The Japan Society for Analytical Chemistry The Award of the Japan Society for Analytical Chemistry
2011/11 - The Japanese Society of Biomaterials The Award of Japanese Society of Biomaterials
2009/03 - the Chemical Society of Japan The Chemical Society of Japan Award for Creative Work

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Association Membership(s) (4)：

THE JAPANESE SOCIETY FOR BIOMATERIALS , THE CHEMICAL SOCIETY OF JAPAN , THE SOCIETY OF POLYMER SCIENCE, JAPAN , THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY

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