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J-GLOBAL ID：201801012360443295 Update date: Mar. 13, 2025

Naohiro Horie

Affiliation and department：
Other affiliations (1)：

Research field (2)： Surgical dentistry , Prosthodontics

Research keywords (8)：口腔外科学 , CCN2 , 口腔癌 , 再生医学 , 軟骨細胞 , FGFR , ゲノム編集 , iPS細胞

Research theme for competitive and other funds (5)：

2024 - 2027 Development of Oral Epithelial Dysplasia Inhibitors Focusing on CTGF
2022 - 2026 癌の骨破壊病変に対するHedgehogシグナルの分子基盤の構築と新たな治療戦略
2021 - 2024 CCN2を応用した新規抗がん剤のスクリーニング
2019 - 2021 Organ-on-a-Chip技術を応用した新規歯胚分化誘導法の開発
2017 - 2019 ゲノム編集を応用したFGFRシグナル制御によるヒトiPS細胞の歯胚分化誘導

Papers (13)：

M. Murata, MA. Kabir, N. Horie, K. Yokozeki, M. Shakya, K. Kusano. Barrier Effects of a poly (lactic acid/caprolactone) Bilayer Membrane for Guided Bone Regeneration on Skull without Periosteum of Adult-Senior Staged Rats. Journal of Clinical and Experimental Dentistry. 2025. e211-e218
Naohiro Horie, Masaru Murata, Yasuhito Minamida, Hiroki Nagayasu, Tsuyoshi Shimo, Toshiyuki Akazawa, Hidetsugu Tsujigiwa, Youssef Haikel, Hitoshi Nagatsuka. Coronal Cementum and Reduced Enamel Epithelium on Occlusal Surface of Impacted Wisdom Tooth in a Human. Dentistry Journal. 2024. 12. 11. 348-348
Naohiro Horie, Shen Chiayin, Tsuyoshi Shimo. The anticancer drug research using CTGF and liquid biopsy. BIO Clinica. 2024. 39. 11. 39-41
Horie N, Kitagawa T, Shimo T. The novel anti-cancer drug screening based on CCN2 and the liquid biopsy technologies. Medical Science Digest. 2023. 49. 10. 497-499
堀江尚弘, 森真理, 佐野聖子, 淀川慎太郎, 南田康人, 永易裕樹, 志茂剛. 口腔感染巣の摘出と継続的な口腔衛生管理により掌蹠膿疱症が改善した1例. 北海道医療大学歯学雑誌. 2023. 42. 1. 27-34

Books (1)：

Lectures and oral presentations (10)：

歯原性角化囊胞内の永久歯歯胚の萌出誘導を行った1 例
(北海道医療大学歯学会第43 回学術大会定例講演会 2025)
舌癌切除標本における苦味受容体TAS2R38 発現の検討
(北海道医療大学歯学会第43 回学術大会定例講演会 2025)
The efect of CTGF on Osteoblast
(The 43rd Annual Meeting of the Dental Society of Health Sciences University of Hokkaido 2025)
The effect of bitter taste receptor (Tas2r) agonist on the oral squamous cell carcinoma
(2025)
The effect of CTGF on the osteoblast
(2024)

Education (2)：

2013 - 2017 東京大学大学院医学系研究科医学博士課程外科学専攻口腔外科学分野
2006 - 2012 Health Sciences University of Hokkaido School of Dentistry Department of Dentistry

Professional career (1)：

Work history (4)：

2021/04 - 現在 Health Sciences University of Hokkaido
2021/04 - 現在 Tohoku University Graduate School of Dentistry
2017/04 - 2021/03 東北大学病院咬合修復科医員
2012/04 - 2013/03 The University of Tokyo Faculty of Medicine University Hospital, Department of Oral-Maxillofacial Surgery,Dentistry and Orthodontics

Committee career (1)：

Awards (1)：

Association Membership(s) (4)：

THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , Japan Prosthodontic Society , 日本口腔科学会 , 日本口腔外科学会

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