Research field (5):
General surgery, pediatric surgery
, Digestive surgery
, Molecular biology
, Experimental pathology
, Tumor diagnostics and therapeutics
Research theme for competitive and other funds (9):
2021 - 2024 Visualization of Cholangiocarcinoma Targeting Claudin 18.2 by Near-Infrared Fluorescently Labeled Antibody
2019 - 2021 Use of VEGFR2 for NIR-guided liver segment labeling
2020 - 2021 Development of a blood anti-SOX2 antibody assay for the early detection of breast cancer
2019 - 2020 エクソソームmicroRNAによる膵癌再発予測マーカーの開発
2016 - 2018 膵癌に対する新規分子標的治療の基盤的研究
2016 - 2017 膵癌に対する新規分子標的治療の基盤的研究
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Papers (33):
Daisuke Kyuno, Terufumi Kubo, Mitsuhiro Tsujiwaki, Shintaro Sugita, Michiko Hosaka, Hazuki Ito, Keisuke Harada, Akira Takasawa, Yusaku Kubota, Kumi Takasawa, et al. COVID-19-associated disseminated mucormycosis: An autopsy case report. World Journal of Clinical Cases. 2022. 10. 28. 10358-10365
Hazuki Ito, Ryuichiro Kakizaki, Keisuke Harada, Daisuke Kyuno, Terufumi Kubo, Naofumi Bunya, Takehiko Kasai, Shuji Uemura, Eichi Narimatsu. Disseminated mucormycosis in a patient with severe COVID-19 on venovenous extracorporeal membrane oxygenation: a case report. IDCases. 2022. e01578
Yui Ito, Akira Takasawa, Kumi Takasawa, Taro Murakami, Taishi Akimoto, Daisuke Kyuno, Yuka Kawata, Kodai Shano, Kurara Kirisawa, Misaki Ota, et al. Aberrant expression of claudin-6 contributes to malignant potentials and drug resistance of cervical adenocarcinoma. Cancer science. 2022. 113. 4. 1519-1530
Daisuke Kyuno, Akira Takasawa, Kumi Takasawa, Yusuke Ono, Tomoyuki Aoyama, Kazufumi Magara, Yuna Nakamori, Ichiro Takemasa, Makoto Osanai. Claudin-18.2 as a therapeutic target in cancers: cumulative findings from basic research and clinical trials. Tissue barriers. 2022. 10. 1. 1967080-1967080
Yu Sato, Tetsuta Satoyoshi, Kenji Okita, Daisuke Kyuno, Atsushi Hamabe, Koichi Okuya, Toshihiko Nishidate, Emi Akizuki, Masayuki Ishii, Hiro-O Yamano, et al. Snapshots of lymphatic pathways in colorectal cancer surgery using near-infrared fluorescence, in vivo and ex vivo. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2021. 47. 12. 3130-3136
及能 大輔, 高澤 啓, 高澤 久美, 真柄 和史, 小山内 誠. 膵癌患者の予後と癌進展におけるJAM-Aの役割(Junctional Adhesion Molecule-A may play a role in the progression of pancreatic cancer). 日本癌学会総会記事. 2022. 81回. J-2053
真柄 和史, 高澤 啓, 高澤 久美, 及能 大輔, 小山内 誠. タイト結合分子JAM-Aの異常高発現が乳がんの悪性化に関与する(Elevated expression of JAM-A contributes malignant progression of breast cancer). 日本癌学会総会記事. 2022. 81回. P-3247
2009 - 2013 Sapporo Medical University Graduate School of Medicine
1999 - 2005 Sapporo Medical University
Professional career (1):
M.D. and Ph.D. (Sapporo Medical University)
Work history (10):
2020/02 - 現在 Sapporo Medical University Department of Pathology Assistant professor
2019/04 - 2020/01 Sapporo Medical University Department of Surgery, Surcial Oncology and Science Clinical Associate
2018/12 - 2019/03 Sapporo Medical University Department of Surgery, Surgical Oncology and Science Clinical Fellow
2016/09 - 2018/11 Heidelberg University Hospital General, Visceral and Transplantation Surgery, Section Surgical Research Visiting Research Scholar
2015/04 - 2016/08 Sapporo Medical University Department of Surgery, Surgical Oncology and Sciencce Clinical Associate
2013/04 - 2015/03 Otaru Ekisaikai Hospital Surgery Clinical Fellow
2009/04 - 2013/03 Sapporo Medical University Department of Surgery Clinical Fellow
2007/04 - 2009/03 Hokkaido Social Service Association Hakodate Hospital Surgery Clinical Fellow
2006/04 - 2007/03 Muroran City General Hospital Junior Resident
2005/04 - 2006/03 Sapporo Medical University Hospital Junior Resident
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Awards (5):
2019/11 - Japanese digestive disease week Young investigator award Exosomes transfer information of cancer cells; reprogramming of nonmetastasizing tumor cells and therapeutic efficacy