Rchr
J-GLOBAL ID：201801013024448293
Update date: Sep. 20, 2024
Nakano Keisuke
Nakano Keisuke
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Oral medicine (pathology)
Research theme for competitive and other funds (30)：
- 2024 - 2028 骨髄由来間葉系幹細胞を起点とした新たな口腔癌転移メカニズムの解明
- 2024 - 2027 Establishment of a foundation for a new diagnostic method for oral cancer with a language model for pathological imaging diagnosis.
- 2023 - 2027 癌骨破壊病変において新規破骨細胞形成促進因子Angiogeninが果たす役割の解明
- 2023 - 2027 Selective induction of bone and cartilage differentiation and reconstruction of the mandibular condyle using miRNA and TCP hybrid biomaterials
- 2023 - 2026 バイオマテリアルin vitro安全性評価のためのgPAD-オルガノイドシステムの開発
- 2023 - 2026 Development of a novel treatment for ameloblastoma by modifying tumor stroma based on CCN2
- 2022 - 2025 口腔癌間質が主導する実質進展制御メカニズム解明と新規治療法開発
- 2021 - 2025 細胞競合による癌の生物学的性格および癌化の制御
- 2020 - 2025 口腔扁平上皮癌における新規遠隔転移抑制治療の開発
- 2020 - 2024 エナメル上皮腫の生物学的性格制御による腫瘍実質ー間質相互作用破綻の誘導
- 2020 - 2023 miRNAが支配する骨・軟骨分化方向決定メカニズムの解明
- 2018 - 2022 Regulation of the biological character of cancer and induction of cancer by the cancer stroma.
- 2017 - 2021 Drug repositioning using the gene promoter activity-based anticancer drug screening system
- 2016 - 2019 Involvement of bone marrow mesenchymal cells in the repair of dentin-pulp complex
- 2016 - 2019 Characterization and potential roles of bone marrow-derived stromal cells in premetastasis niche
- 2014 - 2017 Elucidation of the molecular mechanisms of the periodontal tissue repair
- 2014 - 2017 Molecular pathology of phenotypic chenges in lesions of jow bones
- 2014 - 2017 Pathogenesis research on oro-maxillary cytological proliferative lesions
- 2013 - 2016 Molecular control mechanism of cell suppling, migration and differentiation in remodeling of periodontal ligament
- 2013 - 2016 The effects of music on the pain thresholds and the balance of autonomic nerves
- 2011 - 2013 Elucidation of the molecular mechanisms of tissue repair using stem cells
- 2011 - 2013 Elucidation of the cell differentiation molecular regulation mechanism in proliferative lesions of the oral cavity using bone marrow stem cell transplantation model
- 2010 - 2012 Elucidation of mechanism of drug-induced gingival overgrowth and search for its therapeutic drugs
- 2010 - 2012 Elucidation of molecular regulation mechanism and promotion of the orthodontic remodeling using the bone marrow stem cell
- 2008 - 2010 Molecular regulation system of cytodifferentiation due to mechanical stress
- 2008 - 2010 Molecular mechanism of cyto-differentiation of proliferating bone resorping lesions
- 2007 - 2008 Molecule regulation mechanism of the cytodifferentiation in the remodeling of a maxillo-periodontal tissues from a view point of orthodontics.
- 2000 - 2002 Molecular pathological study of tooth germ and odonto genic tumor
- 2001 - 2001 歯胚の誘導制御における基底膜VI型コラーゲンα鎖の役割
- 1999 - 2001 Gene expression of BMP family and receptors during tooth development
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Papers (204)：
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Kiyofumi Takabatake, Hidetsugu Tsujigiwa, Keisuke Nakano, Anqi Chang, Tianyan Piao, Yasunori Inada, Takuma Arashima, Ayumi Morimatsu, Ayumi Tanaka, Hotaka Kawai, et al. Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate. Materials (Basel, Switzerland). 2024. 17. 16
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Shintaro Sukegawa, Futa Tanaka, Keisuke Nakano, Takeshi Hara, Takanaga Ochiai, Katsumitsu Shimada, Yuta Inoue, Yoshihiro Taki, Fumi Nakai, Yasuhiro Nakai, et al. Training high-performance deep learning classifier for diagnosis in oral cytology using diverse annotations. Scientific reports. 2024. 14. 1. 17591-17591
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中野 敬介, 長塚 仁. 【頭頸部腫瘍II-上気道・口腔・顎顔面骨腫瘍-】口腔・歯原性・顎顔面骨腫瘍のWHO分類改訂のポイント. 病理と臨床. 2024. 42. 7. 0670-0675
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Htoo Shwe Eain, Hotaka Kawai, Masaaki Nakayama, May Wathone Oo, Toshiaki Ohara, Yoko Fukuhara, Kiyofumi Takabatake, Quisheng Shan, Yamin Soe, Kisho Ono, et al. Double-faced CX3CL1 enhances lymphangiogenesis-dependent metastasis in an aggressive subclone of oral squamous cell carcinoma. JCI insight. 2024. 9. 10
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高畠 清文, チャン・アンチ, ピャオ・ティンヤン, リー・ズウシャオ, 河合 穂高, 中野 敬介, 長塚 仁. 口腔癌間質による腫瘍実質の生物学的性格制御について. 日本病理学会会誌. 2024. 113. 1. 353-353
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MISC (110)：
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SOE Yamin, 河合穂高, EAIN Htoo Shwe, 高畠清文, 吉田沙織, 佐能彰, 佐能彰, 森松歩, 中野敬介, 長塚仁. Role of CXCR4 in angiogenesis of oral squamous cell carcinoma. 日本臨床口腔病理学会総会・学術大会プログラム・抄録集(Web). 2023. 34th
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武部祐一郎, 辻極秀次, 高畠清文, 稲田靖則, 藤井昌江, 河合穂高, 中野敬介, 長塚仁. Effect of CCN2 secreted by ameloblastoma on bone resorption through tumor stroma. 日本口腔腫瘍学会総会・学術大会プログラム・抄録集. 2023. 41st
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稲田靖則, 高畠清文, 藤井昌江, 伏見滋子, 中野敬介, 長塚仁. Mechanism of marsupialization in ameloblastomamediated via HIF-1. 日本口腔腫瘍学会総会・学術大会プログラム・抄録集. 2023. 41st
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稲田靖則, 高畠清文, 辻極秀次, 河合穂高, 中野敬介, 長塚仁. ハニカム構造を有するTCPを応用した骨髄組織誘導. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
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高畠清文, 稲田靖則, 藤井昌江, 河合穂高, 中野敬介. HIF-1αを介したエナメル上皮腫開窓術作用機序の解明. 日本口腔科学会学術集会プログラム・抄録集. 2023. 77th
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Books (7)：
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口腔癌 = Oral cancer
医歯薬出版 2023 ISBN:9784263423158
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Clinical Concepts and Practical Management Techniques in Dentistry
IntechOpen 2022 ISBN:9781839628429
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Inflammation and Oral Cancer From Bench to Bedside 1st Edition
Academic Press is an imprint of Elsevier 2021
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新口腔病理学
医歯薬出版 2021 ISBN:9784263458594
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病理組織の見方と鑑別診断
医歯薬出版 2020 ISBN:9784263731970
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Lectures and oral presentations (45)：
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口腔扁平上皮癌腫瘍間質が腫瘍関連マクロファージの集族・分化に与える影響について
(第44回岡山歯学会総会・学術大会 2023)
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口腔細胞診におけるNILM症例についての再検討
(第62回日本臨床細胞学会秋期大会 2023)
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口腔扁平上皮癌における骨髄由来間葉系幹細胞の動態の検討
(第31回硬組織再生生物学会学術大会・総会 2023)
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口腔扁平上皮癌の腫瘍血管形成におけるCXCR4の役割の検討
(第34回日本臨床口腔病理学会 学術大会 2023)
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口腔扁平上皮癌微小環境が腫瘍関連マクロファージ浸潤に与える影響 について
(第34回日本臨床口腔病理学会 学術大会 2023)
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Professional career (2)：
- 修士(学術) (北里大学)
- 博士(歯学) (岡山大学)
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