Rchr
J-GLOBAL ID：201801013468910880
Update date: Dec. 30, 2024 Kon Kazuyoshi
コン カズヨシ | Kon Kazuyoshi
Research field (1)：
Gastroenterology
Research keywords (4)：
alcohol-related liver disease
, lipotoxicity
, oxidative stress
, nonalcoholic steatohepatitis
Research theme for competitive and other funds (16)： - 2023 - 2026 Integrated multiomics analysis to investigate the mechanism of immunotherapy-resistant MAFLD-related hepatocarcinogenesis
- 2021 - 2024 Immunonutritional approach for innate immune dysregulation in metabolic dysfunction-associated fatty liver disease
- 2021 - 2023 Pathogenesis mechanism by changes in lipid metabolism and lipid mediators in alcohol-related/associated liver disease
- 2020 - 2023 Mechanism of enhanced hepatotoxicity through fatty acid metabolic imbalance in the progression of fatty liver disease
- 2017 - 2020 The impact of lipid composition alteration via beta-oxidation failure on the pathophysiological linkage between nonalcoholic steatohepatitis and sarcopenia
- 2016 - 2019 Development of an early diagnosis method targeting nuclear matrix protein for autophagy-related digestive disorder disease
- 2015 - 2018 Innate immune regulation in metabolic steatohepatitis and experimental therapeutics
- 2012 - 2015 New therapeutic strategy to non-alcoholic liver disease targeting on autophagy
- 2012 - 2015 The new strategy of steatohepatitis targeting alteration of epigenetic regulation
- 2012 - 2015 Innate immune regulation of hepatic metabolism and immuno-nutritional approach for nonalcoholic fatty liver disease
- 2009 - 2011 Central role of autophagy in the pathogenesis of gastrointestinal and hepatic diseases.
- 2009 - 2011 Role of innate immune system in the regulation of hepatic metabolism and pathogenesis of steatohepatitis
- 2008 - 2009 The role of endoplasmic reticulum stress and mitochondria-dependent pathway in carcinogenesis of steatohepatitis.
- 2007 - 2008 Pathogenesis and experimental therapeutics of metabolic syndrome-related liver diseases
- 2006 - 2008 The mechanism of drug-induced liver injury and development of drug resistance -involvement of insulin resistance-
- 進行中の研究課題・終了した研究課題
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Akira Uchiyama, Kazuyoshi Kon, Maki Morinaga, Hiroo Fukada, Reiko Yaginuma, Kyoko Fukuhara, Shunhei Yamashina, Kazuhisa Iwabuchi, Kenichi Ikejima. Palmitic acid induces insulin resistance and oxidative stress-mediated cell injury through accumulation of lipid rafts in murine hepatocytes. Biochemical and Biophysical Research Communications. 2025
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Akira Uchiyama, Kazuyoshi Kon, Satoshi Sakuma, Toshifumi Sato, Maki Morinaga, Hiroo Fukada, Hisafumi Yamagata, Reiko Yaginuma, Kyoko Fukuhara, Shunhei Yamashina, et al. Hepatic steatosis and skeletal muscle alterations during the COVID-19 lockdown in a cohort of patients with chronic liver disease in Japan. Hepatology research : the official journal of the Japan Society of Hepatology. 2023
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今 一義, 森永 真紀, 内山 明, 深田 浩大, 佐藤 寿史, 柳沼 礼子, 福原 京子, 山科 俊平, 池嶋 健一. 原発性胆汁性胆管炎のGLOBEスコア高値例における長期予後の検討. 日本消化器病学会雑誌. 2023. 120. 臨増総会. A399-A399
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深田 浩大, 佐藤 寿史, 森永 真紀, 山形 寿文, 内山 明, 柳沼 礼子, 福原 京子, 今 一義, 山科 俊平, 池嶋 健一. ウィズ・コロナ時代とコロナ前のA型・E型肝炎の発生動向の比較. 日本成人病(生活習慣病)学会会誌. 2023. 48. 69-69
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内山 明, 今 一義, 森永 真紀, 深田 浩大, 柳沼 礼子, 福原 京子, 山科 俊平, 池嶋 健一. コロナ禍におけるアルコール性関連肝疾患患者の骨格筋量と肝病態への影響. アルコールと医学生物学. 2022. 41. 48-50
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今 一義, 若穂囲 徹, 入來 晃久. Highlights 学会印象記(第41回アルコール医学生物学研究会学術集会/第5回関東甲信越アルコール関連問題学会新潟大会/第118回日本精神神経学会学術総会). Frontiers in Alcoholism. 2022. 10. 2. 46-49
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佐藤 寿史, 内山 明, 栁沼 礼子, 今 一義, 池嶋 健一. 臓器線維化を捉える : 線維化の非侵襲的評価からデグラドーム解析まで-The search for tracking fibrosis : non-invasive methods and analysis of the plasma degradome-特集 臓器線維化へのアプローチ : 肝臓・膵臓のアンチエイジングを見据えて. Anti-aging medicine / 日本抗加齢医学会 [編]. 2022. 18. 3. 171-176
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Kitazawa Utako, Maruyama Hitoshi, Fukada Hiroo, Morinaga Maki, Nakadera Eisuke, Uchiyama Akira, Yaginuma Reiko, Fukuhara Kyoko, Kon Kazuyoshi, Yamashina Shunhei, et al. A case of aneurysm in the splenorenal collateral treated by BRTO with GERTO in a patient on maintenance dialysis accompanied by alcoholic liver fibrosis. Kanzo. 2022. 63. 6. 286-292
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KON Kazuyoshi. Pathogenesis and epidemiology of alcohol-associated/related liver disease. Nippon Shokakibyo Gakkai Zasshi. 2022. 119. 1. 14-22
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今一義, 石塚敬, 池嶋健一. 脂肪肝炎形成の分子機構とジェントロジー. 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web). 2022. 54th
ｍore...- 2000 - 2004 Juntendo University Graduate School of Medicine
- 1990 - 1996 Juntendo University Faculty of Medicine
- 2023/03 - 現在 Juntendo University School of Medicine Department of Gastroenterology associate professor
- 2011/03 - 2023/03 Juntendo University School of Medicine Department of Gastroenterology associate professor
- 2007/01 - 2011/03 Juntendo University School of Medicine Department of Gastroenterology assistant professor
- 2002/01 - 2004/08 The University of North Carolina at Chapel Hill Department of Cell and Developmental Biology
- 2018/05 - 2023/03 The Japanese Society of Gastroenterology associate editor for Clinical Journal of Gastroenterology
- 2020 - Digital International Liver Congress 2020 Young Investigator Award
- 2009 - The Japan Society of Hepatology Sponsorship Award
- 2007/10 - JDDW Poster session excellent presentation
International Society for Biomedical Research on Alcoholism
, American College of Physicians
, American Association for the Study of Liver Diseases
, 日本抗加齢医学会
, 日本アルコール・アディクション医学会
, 日本消化器内視鏡学会
, 日本消化器病学会
, 日本肝臓学会
, 日本内科学会
