Tanaka Masamitsu

Affiliation and department：
Homepage URL (1)： http://www.med.akita-u.ac.jp/department/gs/kenkyu-org/kouza.php?koza=seika2

Research field (2)： Experimental pathology , Tumor biology

Research keywords (6)：中皮細胞 , ブレブ小胞 , scirrhous , TAM , CAF , stromal cells

Research theme for competitive and other funds (21)：

2022 - 2025 遠隔間質ニッチの形成による癌の拡散メカニズム
2019 - 2023 Analyses of Tumor-Associated Macrophage in Lung Cancer with Next Generation Sequence and Tissue Clearing
2019 - 2021 MΦブレブ小胞によるがん分子情報の新規伝達メカニズム
2017 - 2020 間質の基質変化を追いかける癌の進展機構
2016 - 2019 間質ネットワークが加速するがんの悪性化メカニズム

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Papers (73)：

Kaito Hayashi, Kurara Takagane, Go Itoh, Sei Kuriyama, Souichi Koyota, Kenji Meguro, Yiwei Ling, Tatsuya Abé, Riuko Ohashi, Masakazu Yashiro, et al. Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNBhigh cancer cells accelerates peritoneal dissemination. British Journal of Cancer. 2024
Michinobu Umakoshi, Yukitsugu Kudo-Asabe, Hiroyuki Tsuchie, Zhuo Li, Kei Koyama, Ken Miyabe, Makoto Yoshida, Hiroyuki Nagasawa, Hiroshi Nanjo, Kyoji Okada, et al. Prognostic value of CAF marker expression in the intratumoral and marginal areas of soft tissue sarcoma. Pathobiology : journal of immunopathology, molecular and cellular biology. 2024
Sei Kuriyama, Kuboki Thasaneeya, Go Itoh, Satoru Kidoaki, Masamitsu Tanaka. Glyoxal-methyl-ethylene sulfonic acid fixative enhances the fixation of cytoskeletal structures for Förster resonance energy transfer measurements. Histochemistry and Cell Biology. 2024
田中正光, 堀江美里, 高金くらら, 馬越通信, 後藤明輝, 柳原吾吉. ST3GAL5高発現癌細胞のエクソソームを介した腹膜播種転移前ニッチの形成機構(Exosomes of ST3G5high cancer cells promote peritoneal metastasis by creating a premetastatic niche). 日本病理学会会誌. 2024. 113. 1. 282-282
Misato Horie, Kurara Takagane, Go Itoh, Sei Kuriyama, Kazuyoshi Yanagihara, Masakazu Yashiro, Michinobu Umakoshi, Akiteru Goto, Junichi Arita, Masamitsu Tanaka. Exosomes secreted by ST3GAL5high cancer cells promote peritoneal dissemination by establishing a pre-metastatic microenvironment. Molecular oncology. 2023

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MISC (44)：

田中正光, 堀江美里, 高金くらら, 伊藤剛, 栗山正, 柳原五吉, 八代正和. Exosomes of ST3G5^high cancer cells promote pre-metastatic niche of peritoneal dissemination. 日本癌学会学術総会抄録集(Web). 2023. 82nd
栗山正, 田中正光. PEDF is required for extravasation and mesenchymal to epithelial-like transition of osteosarcoma. 日本癌学会学術総会抄録集(Web). 2020. 79th
栗山正, 田中正光. PEDF overexpression in osteosarcoma cell line increases the endothelial permeability and promotes metastasis. 日本癌学会学術総会抄録集(Web). 2019. 78th
田中正光, 馬越通信, 前田大地, 後藤明輝, 相場なみ子. マクロファージによる癌細胞外小胞の伝搬を介した胃癌の浸潤促進作用. 日本病理学会会誌. 2018. 107. 1. 343-343
Itoh G, Tanaka M. Cancer-stromal cells response controlled by death vesicles. Akita J Med. 2018

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Professional career (1)：

医学博士

Work history (5)：

2009/01 - 現在 Akita University Graduate School of Medicine
2003/04 - 2008/12 国立がん研究センター研究所細胞増殖因子研究部室長
1996/10 - 2003/03 Hamamatsu University School of Medicine
1994/09 - 1996/09 Harvard Medical School, research fellow
1993/04 - 1994/09 日本学術振興会特別研究員

Committee career (1)：

2010 - 現在日本癌学会評議員

Association Membership(s) (3)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE SOCIETY OF PATHOLOGY , THE JAPANESE CANCER ASSOCIATION

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