Tsubota Akihito

ツボタアキヒト | Tsubota Akihito

Affiliation and department：
Job title： Professor

Research field (1)： Gastroenterology

Research theme for competitive and other funds (6)：

2022 - 2025 Intrahepatocellular organelle abnormalities and occult HCV that remain long-term after HCV elimination
2022 - 2025 肝癌特異的な細胞外分泌蛋白を用いた新規早期診断法確立とその実用化に向けた検証研究
2019 - 2023 B型肝炎ウイルスのステルス性による慢性感染成立の機序解明と阻止分子標的の創薬
2015 - 2018 Integrating multiple omics analysis for understanding the pathological mechanism of chronic hepatitis B virus infection and identifying potential molecular targets using humanized chimeric mice
2011 - 2015 Functional analysis of oxidative stress-induced hepatocarcinogenic genes for molecular target treatment

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Papers (362)：

Masanori Atsukawa, Akihito Tsubota, Chisa Kondo, Hidenori Toyoda, Koichi Takaguchi, Makoto Nakamuta, Tsunamasa Watanabe, Asahiro Morishita, Joji Tani, Hironao Okubo, et al. ALBI score predicts morphological changes in esophageal varices following direct-acting antiviral-induced sustained virological response in patients with liver cirrhosis. Journal of gastroenterology. 2024
Norio Itokawa, Masanori Atsukawa, Akihito Tsubota, Toru Ishikawa, Hidenori Toyoda, Koichi Takaguchi, Tsunamasa Watanabe, Chikara Ogawa, Atsushi Hiraoka, Hironao Okubo, et al. Kinetics of the hepatitis B core-related antigen and treatment responses in chronic hepatitis B patients treated with tenofovir alafenamide. Hepatology research : the official journal of the Japan Society of Hepatology. 2024
Chika Nakagawa, Tsunekazu Oikawa, Kohji Yamada, Akihito Tsubota, Chisato Saeki, Kuniko Katagiri, Naoko Tago, Hiroshi Kamioka, Kaoru Ueda, Koichiro Haruki, et al. Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2024. 1-13
Chisato Saeki, Mitsuru Saito, Akihito Tsubota. Association of chronic liver disease with bone diseases and muscle weakness. Journal of bone and mineral metabolism. 2024
Haruyo Aoyagi, Hiroko Iijima, Eman S Gaber, Takuma Zaitsu, Mami Matsuda, Kosho Wakae, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Jeffrey Kahn, et al. Hepatocellular organellar abnormalities following elimination of hepatitis C virus. Liver international : official journal of the International Association for the Study of the Liver. 2023. 43. 8. 1677-1690

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MISC (113)：

及川恒一, 山田幸司, 坪田昭人, 佐伯千里, 上田薫, 神岡洋, 春木孝一郎, 池上徹, 吉田清嗣, 猿田雅之. 早期診断に有用な肝細胞癌特異的バイオマーカー血清PKCδ. 肝細胞研究会プログラム・抄録集. 2023. 30th
中野真範, 及川恒一, 木下勇次, 木下千夏, 富田陽一, 高野啓子, 石田仁也, 高倉一樹, 鳥巣勇一, 石川智久, et al. 当院におけるHIV/HCV重複感染例に対するDAA治療. 日本消化器病学会雑誌(Web). 2019. 116
Etsuko Iio, Noritomo Shimada, Kentaro Matsuura, Masanori Atsukawa, Koichi Takaguchi, Yuichiro Eguchi, Hideyuki Nomura, Noboru Hirashima, Akihito Tsubota, Atsunori Kusakabe, et al. Investigating the association of TLL1 variant with development of hepatocellular carcinoma after eradication of hepatitis C virus by interferon-free regimens. HEPATOLOGY. 2017. 66. 521A-521A
Taeang Arai, Masanori Atsukawa, Tadashi Ikegami, Shigeru Mikami, Noritomo Shimada, Akihito Tsubota, Keizo Kato, Hiroshi Abe, Tomomi Okubo, Ai Nakagawa, et al. Efficacy and safety of ombitasvir/ritonavir/paritaprevir combination therapy for genotype 1b chronic hepatitis C patients complicated with chronic kidney disease. HEPATOLOGY. 2016. 64. 951A-951A
M. Atsukawa, N. Shimada, A. Tsubota, H. Abe, T. Okubo, A. Nakagawa, T. Arai, N. Itokawa, C. Kondo, Y. Tanaka, et al. EFFICACY OF DACLATASVIR/ASUNAPREVIR FOR PATIENTS WITH CHRONIC HEPATITIS C 1B COMPLICATED WITH RENAL INSUFFICIENCY. JOURNAL OF HEPATOLOGY. 2016. 64. S795-S795

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Books (11)：

Management of Gastric Cancer
InTech 2011
Nanocrystal
InTech 2011
ラクトフェリン 2007
2007
C型慢性肝炎治療の新たなストラテジー:インターフェロン治療の今後
先端医学社 2004
先端医療シリーズ25 肝・胆・膵疾患肝・胆・膵疾患の最新医療
先端医療技術研究所 2004

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