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J-GLOBAL ID：201801013873196281 Update date: Apr. 15, 2025

Hirashima Shin-ichi

Affiliation and department：
Homepage URL (1)： https://www.ps.toyaku.ac.jp/yakukagaku/

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (4)：

2022 - 2025 求核部位選択性を鍵とする多彩なリンカルコゲニド類の合成展開
2019 - 2022 Synthesis of chiral phosphorous compounds utilizing sulfur
2016 - 2019 Development of novel push-pull ethylene organocatalysts and their application to synthesis of medicines
2008 - 2009 ヒトと環境に優しい可視光酸素酸化マイクロフローシステムの開発

Papers (75)：

Eiki Hirota, Shin-ichi Hirashima, Chika Tadasue, Anna Suzuki, Yasuyuki Matsushima, Kosuke Nakashima, Tsuyoshi Miura. Synthesizing Chiral Vicinal Bisphosphine Derivatives through Hydrophosphinylation and Asymmetric Protonation of Secondary Phosphine Sulfides with Vinylphosphine Oxides. The Journal of Organic Chemistry. 2025
Taro Koda, Hiroshi Akutsu, Mitsuaki Suzuki, Kosuke Nakashima, Shin-ichi Hirashima, Akihiro Yoshida, Tsuyoshi Miura, Takashi Yamanoi. Asymmetric ε-regioselective conjugate addition of 2-furfuryl ketones to nitroalkenes using a thiourea organocatalyst. Tetrahedron Letters. 2025. 155. 155392-155392
Yasuyuki Matsushima, Yoshiyuki Iijima, Chinatsu Tanabe, Kosuke Nakashima, Shin-ichi Hirashima, Tsuyoshi Miura. Organocatalyzed Asymmetric Conjugate Addition of Cyclic β-Keto Esters to (E)-β-Nitroacrylate Derivatives. Chemistry - An Asian Journal. 2024
Kosuke Nakashima, Dancho Yordanov, Yasuyuki Matsushima, Shin-ichi Hirashima, Tsuyoshi Miura, Anton Georgiev. Rearrangement of C2-Spirooxindoles: Conversion to the 2-Hydroxyhemi-Indigo and Chromenoindole. The Journal of Organic Chemistry. 2024
Yuta Iino, Yasuyuki Matsushima, Kosuke Nakashima, Shin-ichi Hirashima, Tsuyoshi Miura. Organocatalyzed Synthesis of γ-Alkenyl Butenolides via Asymmetric Direct Vinylogous Conjugate Addition-Elimination of Substituted Furanone Derivatives to β-Phenylsulfonylenones. The Journal of Organic Chemistry. 2024

MISC (3)：

佐々木愛理, 林由浩, 木村優花, 韮沢慧, 濱野展人, 片桐文彦, 坂井崇亮, 吉田彰宏, 平島真一, 三浦剛, et al. 筋組織へのターゲティング能を有する全身投与型ナノDDSの開発. 日本筋学会学術集会プログラム・抄録集. 2019. 5回. 100-100
林由浩, 佐々木愛理, 木村優花, 韮沢慧, 濱野展人, 片桐文彦, 坂井崇亮, 吉田彰宏, 平島真一, 三浦剛, et al. A2G80ペプチド修飾リポソームの全身投与による筋組織移行性評価. 日本薬剤学会年会講演要旨集. 2019. 34年会. 182-182
林由浩, 佐々木愛理, 木村優花, 韮沢慧, 濱野展人, 片桐文彦, 坂井崇亮, 吉田彰宏, 平島真一, 三浦剛, et al. A2G80ペプチド修飾リポソームの全身投与による筋組織移行性評価. 日本薬剤学会年会講演要旨集. 2019. 34年会. 182-182

Education (3)：

2007 - 2010 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science
2005 - 2007 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science
2001 - 2005 Gifu Pharmaceutical University Faculty of Pharmaceutical Science Department of Manufacturing Pharmacy

Professional career (1)：

Work history (8)：

2021/04 - 現在 Tokyo University of Pharmacy and Life Sciences
2018/04 - 2021/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
2013/08 - 2018/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
2012/07 - 2013/07 Chubu University Research Institute of Science and Technology
2011/12 - 2012/06 Chubu University

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