- 2022 - 2025 SIGIRR/IL-18Rα複合体形成に基づいた新規抗炎症療法の分子基盤の確立
- 2019 - 2022 Elucidation of the regulation mechanism of cystic fibrosis-specific splice variant expression and development of novel therapeutic strategies
- 2016 - 2019 Therapeutic application to cystic fibrosis based on IL-37 and stabilized cell surface expression of SIGIRR
- 2014 - 2016 Molecular basis of SIGIRR expression and regulatory function in Cystic Fibrosis and its therapeutic approach
- 2010 - 2012 Regulatory mechanism of SIGIRR/TIR8 expressionn LPS-mediated signaling.
- 2008 - 2009 Expression regulation and synthetic pathway of SIGIRR/TIR8, a negative regulator of Toll like receptor signaling
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