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J-GLOBAL ID：201801013994903490 Update date: Dec. 26, 2024

Yahagi Ayano

ヤハギアヤノ | Yahagi Ayano

Affiliation and department：

Research field (3)： Laboratory animal science , Immunology , Bacteriology

Research theme for competitive and other funds (6)：

2022 - 2027 Analysis of organelle functions for the homeostasis of hematopoietic stem cells and platelet production
2020 - 2024 脳梗塞後リハビリテーションによる大脳基底核経路ネットワーク改変メカニズムの解明
2019 - 2022 A novel regulatory mechanism for innate immune signals by ectoenzymes BST-1 and CD38
2017 - 2021 Roles for CD157 in functions of macrophage lineage cells and early pathophysiology of a rheumatoid arthritis model
2017 - 2020 Histological changes of the synovial tissues and involvement of acquired immunity in a murine model for rheumatoid arthritis induced by infection with Mycoplasma fermentans.

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Papers (24)：

Takahiko Akagi, Sumie Hiramatsu-Asano, Kenta Ikeda, Hiroyasu Hirano, Shoko Tsuji, Ayano Yahagi, Masanori Iseki, Makoto Matsuyama, Tak W. Mak, Kazuhisa Nakano, et al. TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1. Frontiers in Immunology. 2022. 13
Takahiko Akagi, Sumie Hiramatsu-Asano, Kenta Ikeda, Hiroyasu Hirano, Shoko Tsuji, Ayano Yahagi, Masanori Iseki, Makoto Matsuyama, Tak W Mak, Kazuhisa Nakano, et al. TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1. Frontiers in immunology. 2022. 13. 926175-926175
Yang Q, Liao M, Wang W, Zhang M, Chen Q, Guo J, Peng B, Huang J, Liu H, Yahagi A, et al. CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production. MBio. 2019. 10. 4
Ayano Yahagi, Taro Saika, Hiroyasu Hirano, Miwa Takai-Imamura, Fumio Tsuji, Hiroyuki Aono, Masanori Iseki, Yoshitaka Morita, Hideya Igarashi, Yukihiko Saeki, et al. IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis. RMD Open. 2019. 5. 2
Taro SAIKA, Yukiyoshi HYO, Hiroya SANO, Masakazu HAMAMOTO, Ayano YAHAGI, Katsuhiko ISHIHARA, Tamotsu HRADA, Hirotaka HARA. Development of a new mouse model of nasal hypersensitivity. 2017. 43. 2. 109-117

MISC (2)：

Masayuki Umemura, Ayano Yahagi, Satoru Hamada, Goro Matsuzaki. IL-17-mediated regulation of innate and acquired immune response against pulmonary mycobacterial infection. JOURNAL OF IMMUNOLOGY. 2006. 176. S112-S112
Umemura M., Kawabe T., Kidoya H., Shudo Koyo, Fukui Masayuki, Asano M., Iwakura Y., Matsuzaki G., Yahagi A., Imamura Ryu, et al. Molecular mechanisms of Fas ligand-induced inflammation. Cancer Research Institute report. 2006. 2003. 113-113

Lectures and oral presentations (9)：

IL-6-PAD4 axis: IL-6 dependent PAD4 production in neutrophils at the earliest phase of arthritis in gp130F759.
(The 48th Annual Meeting of the Japanese for Immunology 2019)
Toll-like receptor-induced Ab production from marginal zone B cells is negatively regulated by ADP-ribosyl cyclase BST-1/CD157
(The 48th Annual Meeting of the Japanese Society for Immunology 2019)
関節リウマチ(RA)モデルgp130F759の最初期変化と<I>M.fermentans</I>の影響
(第34回自己免疫研究会 2019)
CX3CR1-eGFP<SUP>+</SUP> macrophage-like synoviocytes in gp130F759, a mouse model for rheumatoid arthritis
(The 26th International Symposium on Molecular Cell Biology of Macrophages 2019)
BST-1/CD157 negatively regulates marginal zone B cell survival and Ab production induced with Toll-like receptor stimulation
(The 47th Annual Meeting of the Japanese Society for Immunology 2018)

Professional career (1)：

Work history (3)：

2022/06 - 現在 Tokyo Women's Medical University Microscopic and Developmental Anatomy
2022/04 - 2022/06 Kawasaki Medical School
2010/04 - 2022/03 Kawasaki Medical School

Awards (1)：

Association Membership(s) (5)：

日本免疫学会 , 日本細菌学会 , 日本生体防御学会 , Japan College of Rheumatology , The Molecular Biology Society of Japan

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