Rchr
J-GLOBAL ID:201801014160476035   Update date: Jun. 16, 2024

Abe Yoshinori

Abe Yoshinori
Affiliation and department:
Job title: Senior Assistant Professor
Research field  (3): Pathobiochemistry ,  Medical biochemistry ,  Molecular biology
Research keywords  (7): PRMT family ,  慢性炎症 ,  腫瘍 ,  癌 ,  癌幹細胞 ,  Hedgehog ,  シグナル伝達
Research theme for competitive and other funds  (17):
  • 2023 - 2026 空間的な遺伝子解析によるケロイド発生機序の解明と新規治療標的の導出
  • 2023 - 2026 Analysis of arginine methylation signal network in pancreatic cancer to develop the novel cancer therapeutic strategy
  • 2021 - 2025 .
  • 2022 - 2025 アルギニンメチル基転移酵素PRMT5による膵臓癌発症を制御する分子機構の解明
  • 2020 - 2023 PRMT5による新たなケロイド幹細胞制御機構の解明と新治療薬開発への挑戦
Show all
Papers (21):
  • Yoshinori Abe, Takumi Sano, Naoki Otsuka, Masashi Ogawa, Nobuyuki Tanaka. PRMT5-mediated methylation of STAT3 is required for lung cancer stem cell maintenance and tumour growth. Communications Biology. 2024. 7. 1
  • Mamiko Tosa, Yoshinori Abe, Seiko Egawa, Tomoka Hatakeyama, Chihiro Iwaguro, Ryotaro Mitsugi, Ayaka Moriyama, Takumi Sano, Rei Ogawa, Nobuyuki Tanaka. The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target. Communications biology. 2023. 6. 1. 1235-1235
  • Yoshinori Abe, Takumi Sano, Nobuyuki Tanaka. The Role of PRMT5 in Immuno-Oncology. Genes. 2023. 14. 3. 678-678
  • Yusuke Motoji, Ryuji Fukazawa, Ryosuke Matsui, Yoshinori Abe, Ikuno Uehara, Makoto Watanabe, Yoshiaki Hashimoto, Yasuo Miyagi, Noriko Nagi-Miura, Nobuyuki Tanaka, et al. Statins Show Anti-Atherosclerotic Effects by Improving Endothelial Cell Function in a Kawasaki Disease-Like Vasculitis Mouse Model. International Journal of Molecular Sciences. 2022. 23. 24. 16108-16108
  • Yoshinori Abe, Nobuyuki Tanaka. Fine-Tuning of GLI Activity through Arginine Methylation: Its Mechanisms and Function. Cells. 2020. 9. 9. 1973-1973
more...
MISC (31):
  • 佐野匠, 佐野匠, 阿部芳憲, 田中信之. The role of STAT3-PRMT5 activation loop machinery in lung cancer cells. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 阿部芳憲, 田中信之. PRMT5 mediates cancer stemness and acquired drug resistance in EGFR-mutant non-small cell lung cancer. 日本癌学会学術総会抄録集(Web). 2020. 79th
  • 土佐眞美子, 阿部芳憲, 土肥輝之, 小川令. ケロイドにおけるVIII型コラーゲン遺伝子の発現解析. 日本形成外科学会基礎学術集会プログラム・抄録集. 2020. 29th
  • 阿部芳憲, 佐野匠, 田中信之. PRMT5はEGFR変異非小細胞癌において癌幹細胞維持と薬剤耐性獲得に関わる. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
  • 阿部芳憲, 田中信之. 恒常的にhedgehogシグナル伝達経路が活性化した癌細胞におけるMEP50/PRMT5複合体の役割. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
more...
Patents (1):
  • 肺癌治療のための抗癌剤の効果の検査法
Professional career (1):
  • 博士(医学) (東京大学)
Work history (3):
  • 2024/04 - 現在 Nippon Medical School Laboratory of Molecular Analysis Senior Assistant Professor
  • 2003/04 - 2024/03 Nippon Medical School Department of Molecular Oncology, Institute for Medical Sciences
  • 2001/04 - 2003/03 日本学術振興会特別研究員(DC2)
Awards (1):
  • 2009/03 - 日本医科大学 日本医科大学賞 (研究部門)
Association Membership(s) (2):
THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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