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J-GLOBAL ID：201801014596215008 Update date: Dec. 21, 2024

Takeuchi Hiroaki

タケウチヒロアキ | Takeuchi Hiroaki

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Affiliation and department：
Job title： Professor
Other affiliations (2)：

Institute of SCIENCE TOKYO Center for Infectious Disease Education and Analysis (TCIDEA) Deputy Director
Institute of SCIENCE TOKYO Research Infrastructure Management Center, Center for Bioscience Head, BSL3 unit

Homepage URL (1)： https://tcidea-hridc.org

Research field (1)： Virology

Research keywords (7)： SARS-CoV-2 , COVID-19 , Infectious Diseases , HIV , Virus , ウイルスゲノム , AIDS

Research theme for competitive and other funds (17)：

2019 - 現在 Creation of new druggable target to overcome HIV-1 latency via innovative fusion between high-resolution nucleic acid analysis and leading-edge technique for viral dynamics
2021 - デジタル検出技術を基盤としたウイルスの新規感染診断法の開発
2018 - 2021 Research on the development of anti-HIV drugs with a novel mechanism of action to cure HIV
2020 - 新型コロナウイルス(SARS-CoV-2)全ゲノム解析およびCOVID-19病態解明
2017 - 2020 HIV-1潜伏感染メカニズムの多面的解析

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Papers (96)：

Shiro Sonoda, Sho Shimada, Atsushi Sawada, Tomoka Yasuda, Tsuyoshi Shirai, Haruhiko Furusawa, Yukie Tanaka, Kousuke Tanimoto, Hiroaki Takeuchi, Yasunari Miyazaki. Refractory pneumonia due to persistent SARS-CoV-2 infection in an immunocompromised host successfully treated with extended course nirmatrelvir/ ritonavir. ASM Case Reports. 2025
Kento Inoue, Dan Tomomasa, Yu Nakagama, Hiroaki Takeuchi, Yukie Tanaka, Kousuke Tanimoto, Takahiro Kamiya, Takeshi Isoda, Masatoshi Takagi, Keisuke Tanaka, et al. Real-world experience of tixagevimab/cilgavimab prophylaxis in Japanese patients with immunodeficiency. Journal of Infection and Chemotherapy. 2025
Hilary Osaka, Yasuaki Tagashira, Hiroaki Takeuchi, Yukie Tanaka, Kousuke Tanimoto, Yoshiaki Gu. Nosocomial outbreak of SARS-CoV-2 in a hospital ward during the Omicron variant-dominant wave with a review of the relevant literature. Japanese journal of infectious diseases. 2024
Omnia Reda, Kazuaki Monde, Kenji Sugata, Akhinur Rahman, Wajihah Sakhor, Samiul Alam Rajib, Sharmin Nahar Sithi, Benjy Jek Yang Tan, Koki Niimura, Chihiro Motozono, et al. HIV-Tocky system to visualize proviral expression dynamics. Communications Biology. 2024. 7. 1
Kei Taga, Hiroaki Takeuchi. Novel role of host protein SLC25A42 in the HIV-1 reactivation of latent HIV-1 provirus. Microbiology and Immunology. 2024. 68. 3. 90-99

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MISC (12)：

Sayaka SUKEGAWA, Hiroaki TAKEUCHI. Genomics and epidemiology of SARS-CoV-2 lineage ~Current update on SARS-CoV-2 Variants of Interest (VOIs) and Variants of Concern (VOCs)~. 2021. 71. 1. 19-32
Ryuta Sakuma, Hiroaki Takeuchi. SIV replication in human cells. FRONTIERS IN MICROBIOLOGY. 2012. 3. 162-162
Natsuko Inagaki, Hiroaki Takeuchi, Saori Matsuoka, Tetsuro Matano. CRITICAL AMINO ACID RESIDUES FOR FUNCTIONAL INTERACTION BETWEEN N-TERMINAL AND C-TERMINAL DOMAINS IN SIV CAPSID PROTEINS. JOURNAL OF MEDICAL PRIMATOLOGY. 2011. 40. 4. 272-272
高原悠侑, 武内寛明, 石井洋, 高橋尚史, 三浦智行, 五十嵐樹彦, 俣野哲朗. ビルマ産アカゲザルSTV 感染により誘導されるCTL エピトープの探索. 第57 回日本ウイルス学会学術集会、2009 年10月25-27 日、東京. 2009
石井洋, 塚本徹雄, 川田真幹, 武内寛明, 明里宏文, 上野貴将, 滝口雅文, 俣野哲朗. Gag特異的CTLクローンのSIV複製抑制能の解析 (学会抄録). 日本エイズ学会誌. 2008. 10. 4. 473

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Books (1)：

Retroviral Host Cell Factors: APOBEC3G, TRIM5, and Cyclophilins.
2011 ISBN:9789533076652

Lectures and oral presentations (40)：

ヒト免疫不全ウイルス(HIV)潜伏感染維持再活性化相克の分子メカニズム
(第20回霊長類医科学フォーラム 2024)
HIV根治に向けた研究はどこまで進んでいるか
(第73回日本感染症学会東日本地方会学術集会 2024)
Genomics and epidemiology of SARS-CoV-2 lineage
(2024)
【次なる感染症パンデミックに備える】〜COVID-19パンデミックの経験を無駄にしないために〜
(令和5年度第2回公衆衛生専門技術研修:神奈川県衛生研究所・学術講演会 2024)
次なる感染症パンデミックに備えて〜ロボティック・バイオロジーを用いた病原体研究の新たな展開〜
(ソニークリニカルサミット 2024)

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Education (1)：

1999 - 2003 Tohoku University Graduate School, Division of Medical Sciences Department of Virology

Professional career (1)：

Ph.D (Tohoku University)

Work history (16)：

2024/10 - 現在 Institute of SCIENCE TOKYO Center for Bioscience Head, BSL3 unit
2024/10 - 現在 Institute of SCIENCE TOKYO Center for Infectious Disease Education and Analysis (TCIDEA) Deputy Director
2024/10 - 現在 Institute of SCIENCE TOKYO Graduate School of Medical and Dental Sciences, Department of High-risk Infectious Disease Control Professor
2023/11 - 2024/10 Tokyo Medical and Dental University TMDU Center for Infectious Disease Education and Analysis (TCIDEA) Deputy Director
2023/06 - 2024/10 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Department of High-risk Infectious Disease Control Professor

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Committee career (11)：

2023/10 - 現在 Frontiers in Cellular and Infection Microbiology Review Editor
2021/03 - 現在 Frontiers in Virology (Fundarmental Virology) Associate Editor
2021/01 - 現在 The Japanese Society for Virology Councilor
2018/04 - 現在日本エイズ学会日本エイズ学会ウェブサイトWG担当委員
2018/01 - 現在 Microbiology and Immunology Associate Editor

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Awards (7)：

2017/11 - 日本エイズ学会日本エイズ学会ECC山口メモリアルエイズ研究奨励賞(武内寛明) 新規HIV-1感染制御宿主因子の同定およびその機能解明
2017/03 - 東京医科歯科大学免疫学・病態生化学領域合同シンポジウム・最優秀発表賞(武内寛明) HIV-1感染を制御する宿主リン酸化酵素MELK
2017/03 - 東京医科歯科大学免疫学・病態生化学領域合同シンポジウム・優秀若手研究奨励賞(武内寛明) HIV-1感染を制御する宿主リン酸化酵素MELK
2015/11 - 武田科学振興財団武田科学振興財団医学系研究奨励(感染症)(武内寛明) 革新的な抗ウイルス戦略をめざした新規HIV感染制御因子群の機能解析
2008 - 上原記念生命科学財団研究奨励(武内寛明)

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Association Membership(s) (2)：

日本エイズ学会 , 日本ウイルス学会

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