MIYAGAWA TAKU

Affiliation and department：

Research field (1)： Genetics

Research theme for competitive and other funds (12)：

2022 - 2026 DNAメチル化異常がもたらすナルコレプシー発症機構の解明
2021 - 2024 フェノムワイド関連解析及び日本人特異的変異による過眠症の分子基盤の解明
2019 - 2022 メタボローム・ゲノム解析を中心としたナルコレプシーの病態解明と個別化医療への応用
2015 - 2019 Searching for susceptibility genes for narcolepsy, and their application for precision medicine
2014 - 2018 Functional analysis of Ccr3 associated with narcolepsy

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Papers (69)：

Mihoko Shimada, Yosuke Omae, Akiyoshi Kakita, Ramil Gabdulkhaev, Yuki Hitomi, Taku Miyagawa, Makoto Honda, Akihiro Fujimoto, Katsushi Tokunaga. Identification of region-specific gene isoforms in the human brain using long-read transcriptome sequencing. Science advances. 2024. 10. 4. eadj5279
Kugui Yoshida-Tanaka, Mihoko Shimada, Yoshiko Honda, Akihiro Fujimoto, Katsushi Tokunaga, Makoto Honda, Taku Miyagawa. Narcolepsy type I-associated DNA methylation and gene expression changes in the human leukocyte antigen region. Scientific reports. 2023. 13. 1. 10464-10464
Hanna M Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M Yogeshwar, Ryan P Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, et al. Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nature communications. 2023. 14. 1. 2709-2709
Makoto Honda, Yosuke Shigematsu, Mihoko Shimada, Yoshiko Honda, Katsushi Tokunaga, Taku Miyagawa. Low carnitine palmitoyltransferase1 activity is a risk factor for narcolepsy type 1 and other hypersomnia. Sleep. 2022
Taku Miyagawa, Susumu Tanaka, Mihoko Shimada, Noriaki Sakai, Kotomi Tanida, Nozomu Kotorii, Tatayu Kotorii, Yu Ariyoshi, Yuji Hashizume, Kimihiro Ogi, et al. A rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia. NPJ genomic medicine. 2022. 7. 1. 29-29

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MISC (18)：

Takeshi Otowa, Mihoko Shimada-Sugimoto, Taku Miya-gawa, Yoshiya Kawamura, Chihiro Kakiuchi, Tadashi Umekage, Kiyoto Kasai, Katsushi Tokunaga, Tsukasa Sasaki. GENOME-WIDE METHYLATION ANALYSIS OF DEPRESSION IN THE JAPANESE POPULATION. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017. 27. S289-S290
宮川卓, 豊田裕美, 小島裕人, 二神貴臣, 佐治博夫, 三島和夫, 本多裕, 徳永勝士, 本多真. 特発性過眠症の感受性遺伝子の探索. MHC: Major Histocompatibility Complex. 2016. 23. 2Suppl. 116-116
宮川卓, Seik-Soon Seik-Soon, 豊田裕美, 三島和夫, 本多裕, 本多真, 徳永勝士. HLA-DQB1*06:02陰性の真性過眠症候群の感受性遺伝子の探索. 先進医薬研究振興財団研究成果報告集. 2016. 2015年度. 74-75
杉本美穂子, 音羽健司, 宮川卓, 宮川卓, KHOR Seik-Soon, 大前陽輔, 豊岡理人, 柏瀬貢一, 小島裕人, 二神貴臣, et al. パニック症のゲノムワイド関連解析のHLAアリルによる層別解析. MHC (Web). 2016. 23. 2 Suppl
Genetic studies in sleep disorders : susceptibility genes for narcolepsy. 2015. 44. 10. 1403-1408

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Awards (3)：

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