Rchr
J-GLOBAL ID:201801015264093169
Update date: Nov. 27, 2024 Terakawa Tsuyoshi
テラカワ ツヨシ | Terakawa Tsuyoshi
Affiliation and department: Homepage URL (2): https://theory.biophys.kyoto-u.ac.jp/terakawa
,
https://theory.biophys.kyoto-u.ac.jp/terakawa-en Research field (1):
Biophysics
Research keywords (8):
Biophysics
, Single molecule fluorescent microscopy
, Nanopore sequencing
, Molecular dynamics simulation
, DNA replication
, DNA repair
, DNA transcription
, Chromatin structure
Research theme for competitive and other funds (18): - 2023 - 2028 分子シミュレーションとナノポアシーケンスによるヒストンリサイクルのシャペロン機構の解明
- 2024 - 2027 ナノポア解析と分子シミュレーションで探るヒストンリサイクリングの鎖バイアス機構
- 2024 - 2027 エピゲノム継承への分子・細胞スケールブリッジアプローチの推進
- 2024 - 2025 DNAカーテン1分子蛍光イメージングで探る転写因子YY1のDNAループ形成分子機構
- 2024 - 2025 生成系人工知能による高速AFMデータの高解像度化技術の開発
- 2023 - 2024 シミュレーション・イメージング・シーケンサ解析によるヒストン修飾継承機構の解明
- 2021 - 2023 クロマチンカーテン法によるクロマチン凝集の1分子蛍光顕微鏡観察
- 2019 - 2022 DNAカーテンと粗視化シミュレーションによるコンデンシン分子モーターの機構解明
- 2019 - 2022 DNAカーテンによるエピゲノム修飾継承の一分子計測
- 2019 - 2021 金銀・ナノ粒子を用いたコンデンシン分子モーターの超高分解能DNAカーテン測定
- 2019 - 2021 DNAカーテン測定によるヒストン化学修飾がクロマチン凝集に与える影響の解明
- 2018 - 2020 Molecular mechanism of chromatin folding explored by single molecule experiments
- 2018 - 2019 Inheritance of epigenomic modifications explored by DNA curtain
- 2018 - 2019 Elucidation of stepping mechanism of molecular motor Condensin
- 2018 - 2018 Molecular mechanism of chromatin folding explored by single molecule experiments
- 2017 - 2018 Mechanism of Chromatin DNA replication
- 2015 - 2017 Homologous sequence search mechanism of Rad51: Molecular simulations and single molecule experiments
- 2013 - 2015 Target search mechanism of transcription factors in a nucleus: Molecular dynamics and informatics study
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Papers (22): -
Fritz Nagae, Yasuto Murayama, Tsuyoshi Terakawa. Molecular mechanism of parental H3/H4 recycling at a replication fork. Nature Communications. 2024. 15. 1. 9485
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Fritz Nagae, Shoji Takada, Tsuyoshi Terakawa. Histone chaperone Nap1 dismantles an H2A/H2B dimer from a partially unwrapped nucleosome. Nucleic Acids Research. 2023. 51. 11. 5351-5363
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Naotaka Sekiyama, Kiyofumi Takaba, Saori Maki-Yonekura, Ken-ichi Akagi, Yasuko Ohtani, Kayo Imamura, Tsuyoshi Terakawa, Keitaro Yamashita, Daigo Inaoka, Koji Yonekura, et al. ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. Proceedings of the National Academy of Sciences. 2022. 119. 38
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Keisuke Inoue, Shoji Takada, Tsuyoshi Terakawa. Coarse-grained molecular dynamics simulations of base-pair mismatch recognition protein MutS sliding along DNA. Biophysics and Physicobiology. 2022. 19
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Takanori Harashima, Shintaro Fujii, Yuki Jono, Tsuyoshi Terakawa, Noriyuki Kurita, Satoshi Kaneko, Manabu Kiguchi, Tomoaki Nishino. Single-molecule junction spontaneously restored by DNA zipper. Nature Communications. 2021. 12. 1
more... MISC (5): - 寺川 剛. コンデンシンの分子モーター活性を同定. 生物物理. 2018. 58. 2. 89-90
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寺川 剛. 染色体構造の形成をつかさどる分子モーター:コンデンシン. 実験医学. 2018. 36. 3
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寺川 剛. 海外だより ~もし素人がアメリカで実験をはじめたら~. 生物物理. 2017. 57. 2. 117-118
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寺川 剛. コンデンシン複合体はDNAに沿って移動する メカノケミカルモーターである. サイエンス誌に載った日本人研究者. 2017. 55-55
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寺川 剛. リコンビナーゼRad51/RecAファミリーによる 塩基トリプレット歩進. サイエンス誌に載った日本人研究者. 2015. 55-55
Lectures and oral presentations (28): -
Molecular Dynamics of Histone Recycling in Chromatin Replication
(The 47th Annual Meeting of the Molecular Biology Society of Japn 2024)
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Reconstitution of chromatin replication-coupled symmetric histone recycling
(5th East Asian Single-Molecule Biophysics Symposium 2024)
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Biophysical approaches to the molecular mechanisms of histone recycling
(2024)
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Unveiling the molecular mechanism of histone recycling through biophysical approaches
(21st IUPAB Congress 2024 2024)
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Exploration of the molecular mechanism of histone recycling through molecular dynamics simulations, nanopore sequencing, and biochemical experiments
(68th Annual Meeting of the Biophysical Society 2024)
more... Education (2): - 2009 - 2014 Kyoto University Graduate School of Science Department of Biophysics
- 2005 - 2009 Tokyo University of Science Faculty of Science and Technology Department of Applied Biological Science
Professional career (1): Work history (6): Awards (4): - 2023/06 - Biophysical Society of Japan Biophysics and Physicobiology Editors' Choice Award
- 2018/09 - The Biophysical Society of Japan Early Career Award in Biophysics
- 2013/09 - Japan Society for Molecular Science Best Oral Presentation Award
- 2012/06 - Protein Science Society of Japan Best Poster Award
Association Membership(s) (3):
Japan Society for Molecular Science
, THE BIOPHYSICAL SOCIETY OF JAPAN
, Biophysical Society
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