2016 - 2018 Analysis of mechanism of a novel cancersuressor derived from microorganism
2014 - 2017 Elucidation of the vesicular trafficking mechanism for prion propagation on the basis of our previous findings of the disturbed vesicular trafficking in prion disease
2013 - 2016 プリオン蛋白質欠損マウスを用いた、インフルエンザ脳症の発症機序の解明
2011 - 2013 患者の重症度を目視で評価する「ATP発色診断法」の開発
2011 - 2013 New target and therapeutic approach to influenza virus-induced multiple organ failure
2011 - 2013 Studies on real-time biomarker of illness severity inthe patients of critical illness and development of the diagnosis machine
2011 - 2013 The analysis of host response determining the severe influenza and HIV infection.
2010 - 2011 患者のそばで使用可能な「ATP 簡易測定器」の研究開発
2009 - 2011 Elucidation of the molecular mechanisms of influenza-associated encephalopathy due to disorder of ATP generation in mitochondria
2009 - 2011 Development of new therapeutics for a highly pathogenic influenza virus infection by inhibition of virus entry and multiplication
2008 - 2009 Extraction and quantification of adenosine triphosphate in mammalian tissues and cells
2008 - 2009 患者のそばで使用可能な「ATP 測定装置」の開発
2007 - 2009 Elucidation of the molecular mechanism of influenza-associated encephalopathy due to disorder of ATP generation in mitochondria
Hideyuki Hara, Junji Chida, Batzaya Batchuluun, Etsuhisa Takahashi, Hiroshi Kido, Suehiro Sakaguchi. Protective role of cytosolic prion protein against virus infection in prion-infected cells. Journal of Virology. 2024. 98. 9
Hideyuki Hara, Hironori Miyata, Junji Chida, Suehiro Sakaguchi. Strain-dependent role of copper in prion disease through binding to histidine residues in the N-terminal domain of prion protein. Journal of Neurochemistry. 2023
Agriani Dini Pasiana, Hironori Miyata, Junji Chida, Hideyuki Hara, Morikazu Imamura, Ryuichiro Atarashi, Suehiro Sakaguchi. Central residues in prion protein PrPC are crucial for its conversion into the pathogenic isoform. Journal of Biological Chemistry. 2022. 298. 9. 102381-102381
Hideyuki Hara, Junji Chida, Keiji Uchiyama, Agriani Dini Pasiana, Etsuhisa Takahashi, Hiroshi Kido, Suehiro Sakaguchi. Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells. Scientific Reports. 2021. 11. 1
Keine Nishiyama, Ryohei Mizukami, Shizuka Kuki, Akihiko Ishida, Junji Chida, Hiroshi Kido, Masatoshi Maeki, Hirofumi Tani, Manabu Tokeshi. Electrochemical enzyme-based blood ATP and lactate sensor for a rapid and straightforward evaluation of illness severity. Biosensors and Bioelectronics. 2021. 198. 113832-113832
Suehiro Sakaguchi, Junji Chida. Prion Protein is a Novel Modulator of Influenza: Potential Implications for Anti-Influenza Therapeutics. Current Issues in Molecular Biology. 2020. 21-32
Chida J, Kido H, Sakaguchi S. Development of novel therapeutics targeting host molecules for influenza. Bio Clinica. 2018. 256. 33. 52-55
Sakaguchi S, Chida J. Roles of prion protein in virus infections. DNA Cell Biol. 2018. PMID: 30222366
Junji Chida, Hiroshi Kido. Extraction and quantification of adenosine triphosphate in mammalian tissues and cells. Methods in Molecular Biology. 2014. 1098. 21-32
2005/12 - International Conference on Mitochondria and Life Asian Mitochondrial Young Investigator Awards A new approach to disrupt certain mitochondrial genes in Dictyostelium cells.
2005/03 - 東北大学大学院 学科長賞 分化統御面におけるミトコンドリア及びミトコンドリア DNA (mtDNA) の多面的機能 : 細胞性粘菌の発生系を用いた解析
JAPAN SOCIETY FOR PROTEASES IN PATHOPHYSIOLOGY
, THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE INTERNATIONAL PROTEOLYSIS SOCIETY
, 日本ウイルス学会
