Rchr
J-GLOBAL ID:201801015483496309   Update date: Sep. 09, 2024

Chida Junji

チダ ジュンジ | Chida Junji
Affiliation and department:
Research field  (4): Immunology ,  Molecular biology ,  Neuroscience - general ,  Virology
Research keywords  (5): マクロファージ ,  Mitochondria ,  Energy metabolism ,  Prion protein ,  Influenza virus
Research theme for competitive and other funds  (23):
  • 2022 - 2024 宿主の炎症性マクロファージを標的とした新興感染症に対する原因療法の開発
  • 2019 - 2022 Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice
  • 2019 - 2022 Elucidation of the pathogenic mechanism and screening of therapeutic compounds in prion disease
  • 2019 - 2021 抗プリオン蛋白質抗体を用いた抗炎症性 M2 マクロファージによる非アルコール性脂肪肝炎 (NASH) の治療法開発研究
  • 2019 - 2021 肺のプリオン蛋白質を分子標的としたインフルエンザ重症化予防の確立
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Papers (43):
  • Hideyuki Hara, Hironori Miyata, Junji Chida, Suehiro Sakaguchi. Strain-dependent role of copper in prion disease through binding to histidine residues in the N-terminal domain of prion protein. Journal of Neurochemistry. 2023
  • Agriani Dini Pasiana, Hironori Miyata, Junji Chida, Hideyuki Hara, Morikazu Imamura, Ryuichiro Atarashi, Suehiro Sakaguchi. Central residues in prion protein PrPC are crucial for its conversion into the pathogenic isoform. Journal of Biological Chemistry. 2022. 298. 9. 102381-102381
  • Hideyuki Hara, Junji Chida, Keiji Uchiyama, Agriani Dini Pasiana, Etsuhisa Takahashi, Hiroshi Kido, Suehiro Sakaguchi. Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells. Scientific Reports. 2021. 11. 1
  • Keine Nishiyama, Ryohei Mizukami, Shizuka Kuki, Akihiko Ishida, Junji Chida, Hiroshi Kido, Masatoshi Maeki, Hirofumi Tani, Manabu Tokeshi. Electrochemical enzyme-based blood ATP and lactate sensor for a rapid and straightforward evaluation of illness severity. Biosensors and Bioelectronics. 2021. 198. 113832-113832
  • Keiji Uchiyama, Hideyuki Hara, Junji Chida, Agriani Dini Pasiana, Morikazu Imamura, Tsuyoshi Mori, Hanae Takatsuki, Ryuichiro Atarashi, Suehiro Sakaguchi. Ethanolamine Is a New Anti-Prion Compound. International Journal of Molecular Sciences. 2021. 22. 21. 11742-11742
more...
MISC (23):
  • Suehiro Sakaguchi, Junji Chida. Prion Protein is a Novel Modulator of Influenza: Potential Implications for Anti-Influenza Therapeutics. Current Issues in Molecular Biology. 2020. 21-32
  • Chida J, Sakaguchi S. Cellular prion protein-mediated protection against influenza A virus infection. Future Virology. 2018. In press
  • Chida J, Kido H, Sakaguchi S. Development of novel therapeutics targeting host molecules for influenza. Bio Clinica. 2018. 256. 33. 52-55
  • Sakaguchi S, Chida J. Roles of prion protein in virus infections. DNA Cell Biol. 2018. PMID: 30222366
  • Junji Chida, Hiroshi Kido. Extraction and quantification of adenosine triphosphate in mammalian tissues and cells. Methods in Molecular Biology. 2014. 1098. 21-32
more...
Patents (5):
  • 血液検体の ATP 測定方法及びキット
  • インフルエンザウイルス感染症の予防・治療剤
  • 病気の重症度の検査方法
  • インフルエンザの治療剤または予防剤
  • ヌクレオチドの抽出方法
Education (1):
  • 2003 - 2006 東北大学大学院 理学部 生命科学研究科 (理学博士)
Work history (4):
  • 2022/04 - 現在 The University of Tokushima
  • 2012/04 - 2022/03 徳島大学 先端酵素学研究所 次世代酵素学研究領域 神経変性病態学分野 助教
  • 2008/02 - 2012/03 The University of Tokushima The Institute for Enzyme Research
  • 2006/04 - 2008/01 The University of Tokushima
Awards (5):
  • 2007/06 - 日本病態プロテアーゼ学会 研究奨励賞 プラスミノーゲン欠損マウスを用いたインフルエンザウイルスの増殖機構の解析
  • 2006/03 - 東北大学 東北大学大学院学科長賞
  • 2005/12 - International Conference on Mitochondria and Life Asian Mitochondrial Young Investigator Awards A new approach to disrupt certain mitochondrial genes in Dictyostelium cells.
  • 2005/03 - 東北大学大学院 学科長賞 分化統御面におけるミトコンドリア及びミトコンドリア DNA (mtDNA) の多面的機能 : 細胞性粘菌の発生系を用いた解析
  • 2004/12 - 日本植物学会 (東北支部) 大会 最優秀学術賞 Dictyostelium discoideum の分化・形態形成における mtDNA の多面的な機能
Association Membership(s) (5):
JAPAN SOCIETY FOR PROTEASES IN PATHOPHYSIOLOGY ,  THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE INTERNATIONAL PROTEOLYSIS SOCIETY ,  日本ウイルス学会
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