2015 - 2018 Phosphorylase phosphorylation in the heart failure development
2015 - 2017 限られたアミノ酸のみから原始タンパク質が構築できるか?
2014 - 2017 Influence of genetic polymorphism on three-dimensional structure and structural flexibility of drug metabolizing enzyme
2013 - 2016 Application of chemical biology to a mechanistic study of human nucleotide excision repair
2013 - 2015 Analysis of a novel small-molecule compound inducing the degradation of a cisplatin resistance-related factor ERCC1
2011 - 2013 Development of the protein-ligand docking program using multi-objective optimization and interactive optimization
2007 - 2008 Computational studies for ligand binding mechanisms of drug metabolizing enzymes with genetic polymorphism
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Papers (130)：
Ayato Mizuno, Tomoki Nakayoshi, Eiji Kurimoto, Koichi Kato, Akifumi Oda. Quantum Chemical Calculations of the Nonenzymatic Bicarbonate Ion-Catalyzed Lactamization of Ornithine Residues to Identify the Components of Primitive Proteins. The Journal of Physical Chemistry A. 2025
Koichi Kato, Tomoki Nakayoshi, Ayato Mizuno, Mayuka Yabu, Eiji Kurimoto, Akifumi Oda. Molecular dynamics simulations of putative primitive proteins including β-aspartic acid residues. Bulletin of the Chemical Society of Japan. 2025. 98. 1
Shuki Yamazaki, Eiji Hishinuma, Yuma Suzuki, Akiko Ueda, Caroline Kijogi, Tomoki Nakayoshi, Akifumi Oda, Sakae Saito, Shu Tadaka, Kengo Kinoshita, et al. Functional significance of CYP2B6 gene rare allelic variants identified in Japanese individuals. Biochemical Pharmacology. 2024. 116515-116515
Ayato Mizuno, Tomoki Nakayoshi, Koichi Kato, Eiji Kurimoto, Akifumi Oda. Computational Estimation of Residues Involving Resistance to the SARS-CoV-2 Main Protease Inhibitor Ensitrelvir Based on Virtual Alanine Scan of the Active Site. Biological and Pharmaceutical Bulletin. 2024. 47. 5. 967-977
Koichi Kato, Tomoki Nakayoshi, Yasuro Shinohara, Eiji Kurimoto, Akifumi Oda, Yoshinobu Ishikawa. Theoretical Studies on the Reaction Mechanism of Schiff Base Formation from Hexoses. The Journal of Physical Chemistry B. 2024. 128. 20. 4952-4958
矢崎望歩, 仲吉朝希, 仲吉朝希, 加藤紘一, 加藤紘一, 水谷衣美, 菱沼英史, 平塚真弘, 平塚真弘, 栗本英治, et al. Molecular dynamics simulation for conformational analysis of CYP3A4 variants and estimation of their effects on enzyme activity. 日本薬学会年会要旨集(Web). 2024. 144th
大森悠生, 菱沼英史, 菱沼英史, 上田昭子, 山崎柊紀, 鈴木祐眞, 佐藤裕, 仲吉朝希, 小田彰史, 斎藤さかえ, et al. Functional characterization of 27 CYP2E1 variants identified in 8,380 Japanese indivisuals. 日本薬学会年会要旨集(Web). 2024. 144th
山崎柊紀, 菱沼英史, 菱沼英史, 上田昭子, 前川正充, 前川正充, 前川正充, 佐藤裕, 公文代將希, 眞野成康, et al. Functional characterization of CYP2B6 rare variants identified in 8,380 Japanese individuals. 日本薬学会年会要旨集(Web). 2023. 143rd
