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J-GLOBAL ID：201801016520591860 Update date: Apr. 21, 2025

INOKUMA Tsubasa

いのくまつばさ | INOKUMA Tsubasa

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Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (10)：

2025 - 2026 新規生物活性ペプチドの創出を指向したα-アミノリン酸含有ペプチドの側鎖網羅的合成法の開発
2022 - 2024 Development of the strategy for synthesis of supersulfides based on rationally-designed sulfuration reagent
2022 - 2023 Direct Introduction of Side Chain Structure to Meddle Molecule Peptides and its Application to the Development of Novel Protease Inhibitory Peptides
2020 - 2023 Synthesis of aminophosphoric acid-containing peptides based on direct asymmetric reaction to iminophosphoric acid peptides
2018 - 2020 Asymmetric construction of arylglycine unit and application to the synthesis of unnatural amino acid-containing peptide

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Papers (68)：

Akiko Yamada, Akira Watanabe, Atsushi Nara, Tsubasa Inokuma, Masatake Asano, Yasuo Shinohara, Takenori Yamamoto. Multiple Inhibitory Mechanisms of DS16570511 Targeting Mitochondrial Calcium Uptake: Insights from Biochemical Analysis of Rat Liver Mitochondria. International Journal of Molecular Sciences. 2025. 26. 6. 2670-2670
Chunzhao Sun, Hiromichi Nishikawa, Tsubasa Inokuma, Ken-ichi Yamada. Diastereodivergent Construction of Octahydrophenanthridinone and Octahydrophenanthridine Cores. Molecules. 2025. 30. 2. 371-371
Tsubasa Inokuma, Ken-ichi Yamada. Improvement of Asymmetric Reactions via Remote Electronic Tuning of N-Heterocyclic Carbene Catalysts. ChemCatChem. 2024. 16. e202401078
Tsubasa Inokuma, Ken-ichi Yamada. Remote Electronic Tuning for High-performance N-Heterocyclic Carbene Catalysis. Journal of Synthetic Organic Chemistry, Japan. 2024. 82. 3. 222-233
Chunzhao Sun, Tsubasa Inokuma, Daisuke Tsuji, Yousuke Yamaoka, Reiko Akagi, Ken-ichi Yamada. Total Synthesis of 1,4a-di-epi-ent-Pancratistatin, Exemplifying a Stereodivergent Approach to Pancratistatin Isomers. Chemical Communications. 2024. 60. 53. 6757-6760

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MISC (29)：

Daishiroh Kobayashi, Kohdai Nishida, Tsubasa Inokuma, Akira Shigenaga, Akira Otaka. Lossen rearrangement-mediated preparation of N-glyoxylyl peptide without addition of oxidant,. Peptide Science 2019. 2020. 59
Taiki Kohiki, Yusuke Kato, Masaya Denda, Yusuke Nishikawa, Kazuko YORITA, Ikuko Sagawa, Tsubasa Inokuma, Akira Shigenaga, Kiyoshi Fukui, Akira Otaka. Development and application of novel protein labeling reagent "SEAL". Peptide Science 2018. 2019. 104-104
Chiaki Komiya, Jun Tsukimoto, Masahiro Ueda, Takuya Morisaki, Tsubasa Inokuma, Akira Shigenaga, Kouji Itou, Akira Otaka. Preparation of protein thioesters enabled by carboxypeptidase-mediated C-terminal specific hydrazinolysis. Peptide Science 2018. 2019. 8-8
Naoto Naruse, Kento Ohkawachi, Tsubasa Inokuma, Akira Shigenaga, Akira Otaka. N-S-acyl-transfer-mediated On-resin Formation of Thioester with Practical Application to Peptide Synthesis. Peptide Science 2017. 2018. 32-33
Chiaki Komiya, Jun Tsukimoto, Takuya Morisaki, Yusuke Tsuda, Rin Miyajima, Tsubasa Inokuma. Development of methodology for producing thioesters from naturally occurring peptide sequence. Peptide Science 2017. 2018. 86-87

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Lectures and oral presentations (203)：

Development of novel sulfur reagents for the controlled chemical synthesis of supersulfides
(Redox Week in Sendai 2025 2025)
アルデヒドのα-チオ基転位反応による脂肪族チオエステルの合成
(日本薬学会第145年会(福岡) 2025)
段階的な硫黄原子の伸長による非対称ペンタスルフィドの合成
(日本薬学会第145年会(福岡) 2025)
ビスフェニルメンチルアルキリデンマロネートを用いる不斉シクロプロパン化の開発とシクロプロパンアミノ酸合成への応用
(日本薬学会第145年会(福岡) 2025)
Development of a Novel Methodology for Supersulfide Synthesis via One-by-One Sulfur Elongation
(2025)

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Education (3)：

2008 - 京都大学大学院薬学研究科博士後期課程中途退学
2007 - 京都大学大学院薬学研究科修士課程修了
2005 - 京都大学薬学部総合薬学科卒業

Professional career (1)：

博士(薬学) (京都大学)

Work history (7)：

2022/04 - 現在 The University of Tokushima
2017/04 - 2022/03 The University of Tokushima
2015/04 - 2017/03 The University of Tokushima
2013/09 - 2015/03 The University of Tokushima
2012/01 - 2013/08 The Scripps Research Institute

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Committee career (2)：

2021/04 - 2023/03 日本薬学会ファルマシアトピックス小委員
2018/04 - 2020/03 科学技術予測センター専門調査員

Awards (5)：

2021/10 - 徳島県令和3年度徳島県科学技術大賞(若手研究者部門)
2020/12 - 令和2年度徳島大学若手研究者学長表彰多様な側鎖構造をもつ異常アミノ酸類縁体およびペプチド群の効率的かつ迅速合成法の開発
2020/03/25 - The Pharmaceutical Society of Japan 2020年度日本薬学会奨励賞 Synthesis of non-canonical amino acids and peptides containing them for establishment of the template for drug discovery
2017/10/21 - 日本薬学会中国四国支部平成29年度日本薬学会中国四国支部奨励賞ペプチドへの直接的不斉反応を基盤とした非天然アミノ酸含有ペプチドの新規効率的不斉合成法開発
2016/12 - The Society of Synthetic Organic Chemistry,Japan 塩野義製薬研究企画賞ペプチドへの直接的不斉マンニッヒ反応を基盤とする新規効率的中分子合成法の開発

Association Membership(s) (5)：

American Chemical Society , The Japanese Peptide Society , The Society of Synthetic Organic Chemistry,Japan , The Pharmaceutical Society of Japan , 日本ケミカルバイオロジー学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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