2020 - 2022 Development of mice model for elucidating the mechanism of healthy life expectancy extension
2019 - 2022 Development of radioprotectors that selectively protect normal tissues
2018 - 2021 Study of biological effects of ionizing radiation on mitochondria
2017 - 2021 A novel study on the mechanisms of low-dose radiation-induced aging and carcinogenesis
2017 - 2020 Mechanism of low dose(rate) radiation induced tumor development by using intestinal stem cell organoid system
2014 - 2018 Elucidation of the mechanisms of low dose, low dose-rate radiation induced mammary cancer through the interaction between mammary stem cells and their microenvironment
2013 - 2017 Molecular mechanism of radiation induced-leukemia using the animal model
2015 - 2016 Low-dose radiation risk assessment through investigating the mechanisms of low-dose radiation induced EMT
2013 - 2016 Development of mouse model susceptible to radiation-induced carcinogenesis at low dose and low dose rate and evaluation of radiation-induced cancer risk
2013 - 2015 Development of bio-dosimetry methods using radiation responsive urinary biomarker
2010 - 2012 The role of translesion DNA synthesis on radiation and chemical induced carcinogenesis
2010 - 2012 Development of a biological dosimeter to detect the DNA damage induced by low dose radiation and carcinogenic risk evaluation
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Papers (56)：
Toyoshima-Sasatani, Megumi, Imura, Fumika, Hamatake, Yuko, Fukunaga, Akihiro, Negishi, Tomoe. Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in Drosophila. GENES AND ENVIRONMENT. 2023. 45. 1
Suzuki, Keiji, Imaoka, Tatsuhiko, Tomita, Masanori, Sasatani, Megumi, Doi, Kazutaka, Tanaka, Satoshi, Kai, Michiaki, Yamada, Yutaka, Kakinuma, Shizuko. Molecular and cellular basis of the dose-rate-dependent adverse effects of radiation exposure in animal models. Part II: Hematopoietic system, lung and liver. JOURNAL OF RADIATION RESEARCH. 2023. 64. 2. 228-249
Suzuki, Keiji, Imaoka, Tatsuhiko, Tomita, Masanori, Sasatani, Megumi, Doi, Kazutaka, Tanaka, Satoshi, Kai, Michiaki, Yamada, Yutaka, Kakinuma, Shizuko. Molecular and cellular basis of the dose-rate-dependent adverse effects of radiation exposure in animal models. Part I: Mammary gland and digestive tract. JOURNAL OF RADIATION RESEARCH. 2023. 64. 2. 210-227
清水 なつみ, 河合 秀彦, 笹谷 めぐみ, 遠藤 充浩, 稲葉 俊哉, 神谷 研二. The effect of low dose radiation on the development of pre-implantation embryos. 長崎医学会雑誌. 2016. 91. 0. 290-292
The molecular mechanisms of the biological effect of low-dose radiation exposure on mammary glands. 2016. 69. 4. 302-304
2001 - 2005 Kyoto University Graduate School of Medicine Phisiology
1999 - 2001 Okayama University Graduate School of Natural Science and Technology Divisions of Pharmaceutical Science and Clinical Pharmaceutical Science
1995 - 1999 Okayama University Faculty of Pharmaceutical Science
1995 - 1999 Okayama University Faculty of Pharmaceutical Science
Professional career (2)：
Master of Pharmaceutical Science (Okayama University)
Ph.D. (Kyoto University)
Work history (5)：
2018/02/01 - Hiroshima University Research Institute for Radiation Biology and Medicine Associate Professor
2007/04/01 - 2018/01/31 Hiroshima University Research Institute for Radiation Biology and Medicine Assistant Professor
2006/04/01 - 2007/03/31 Kyoto University Graduate School of Medicine Research Associate
2005/04/01 - 2006/03/31 Kyoto University Radiation Biology Center Part-time Researcher
2003/04/01 - 2005/03/31 JSPS Research Fellow, Japan Society for the Promotion of Science
The Japan Radiation Research Society
, The Molecular Biology Society of Japan
, The Japanese Environmental Mutagen Society (JEMS)
, Japanese Cancer Association
