Mokuda Sho

モクダショウ | Mokuda Sho

Research field (1)： Allergies and connective tissue disease

Research theme for competitive and other funds (16)：

2023 - 2026 イントロン型マイクロRNA・宿主遺伝子間の協調的機能の解析とその相乗効果を利用した関節疾患に対する核酸医薬の開発
2022 - 2025 炎症性サイトカインによる宿主受容体発現調節を利用したCOVID-19治療薬の開発
2023 - 2024 関節リウマチ・膠原病疾患におけるサイトカイン及び成長因子の網羅的解析
2023 - 2024 炎症誘導性宿主受容体NRP2の制御を介したCOVID-19新規治療法の開発
2022 - 2024 関節疾患における軟骨障害の新規治療法としてのmRNA医薬の開発に関する基礎的研究

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Papers (59)：

Naoyuki Ueda, Sho Mokuda, Tomokazu Kawaoka, Shinsuke Uchikawa, Kei Amioka, Masataka Tsuge, Kana Asada, Yuri Okada, Yui Kobayashi, Mai Ishikawa, et al. Influence of dispersion slope on the diagnosis of liver fibrosis by the shear wave in metabolic dysfunction-associated steatotic liver disease. Hepatology Research. 2024
Minori Tabata, Rie Nakai, Kyoko Kajihara, Hiromi Nakagawa, Shinichi Yamasaki, Fumiaki Hayashi, Sho Mokuda. Performance evaluation and user experience of BT-50 transportation unit with automated and scheduled quality control measurements. Clinical Chemistry and Laboratory Medicine (CCLM). 2024
Chihaya Watanabe, Yusuke Yoshida, Genki Kidoguchi, Hiroki Kitagawa, Takeshi Shoji, Naoki Nakamoto, Naoya Oka, Tomohiro Sugimoto, Sho Mokuda, Shintaro Hirata. Disseminated Mycobacterium abscessus infection with osteoarticular manifestations as an important differential diagnosis of inflammatory arthritis: A case report and literature review. Modern Rheumatology Case Reports. 2023. 8. 1. 49-54
Yusuke Yoshida, Naoya Oka, Ai Yorishima, Sho Masuda, Michinori Ishitoku, Kei Araki, Hiroki Kohno, Hirofumi Watanabe, Tomohiro Sugimoto, Sho Mokuda, et al. Safe Introduction of Hydroxychloroquine Focusing on Early Intolerance Due to Adverse Drug Reactions in Patients with Systemic Lupus Erythematosus. Internal medicine (Tokyo, Japan). 2023. 62. 14. 2051-2057
Michinori Ishitoku, Sho Mokuda, Kei Araki, Hirofumi Watanabe, Hiroki Kohno, Tomohiro Sugimoto, Yusuke Yoshida, Takemasa Sakaguchi, Junya Masumoto, Shintaro Hirata, et al. Tumor Necrosis Factor and Interleukin-1β Upregulate NRP2 Expression and Promote SARS-CoV-2 Proliferation. Viruses. 2023. 15. 7

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MISC (5)：

Genome editing elucidates the mechanisms of cranial development and cartilage homeostasis : to detect the coherence between intronic miRNA and host gene. 医学のあゆみ. 2020. 273. 9. 853-858
Ito Y, Mokuda S, Miyata K, Matsushima T, Asahara H. MicroRNAs in Chronic Inflammation Diseases. Chronic Inflammation (Chapter 6) 2016 Springer Japan. Review. Book. 2016
金子直恵, 伊藤有紀, 岩崎智之, 竹田浩之, 澤崎達也, 右田清志, 上松一永, 川上純, 森川紳之祐, 茂久田翔, et al. 無細胞AIM2インフラマソームの構築. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [1P0390]-[1P0390]
J. Masumoto, R. Sugiyama, K. Agematsu, K. Migita, J. Nakayama, S. Mokuda, F. Ogura, K. Haraikawa, C. Okumura, S. Suehiro, et al. Defect of Suppression of Inflammasome-Independent Interleukin-8 Secretion from SW982 Synovial Sarcoma Cells By Familial Mediterranean Fever-Derived Pyrin Mutations. JOURNAL OF CLINICAL IMMUNOLOGY. 2014. 34. S195-S196
The progress of clinical laboratory assessments in rheumatoid arthritis. 2014. 58. 9. 1004-1009

Books (2)：

リウマチ性多発筋痛症
臨床検査(医学書院) 2021
関節リウマチとサイトカインを標的とした生物学的製剤
炎症と再生(先端医学社) 2020

Awards (9)：

2022/08 - 第42回日本炎症・再生医学会優秀演題賞
2021/04 - 令和3年度日本リウマチ学会奨励賞
2020/11 - 令和2年度日本臨床検査医学会若手研究者奨励賞
2016/06 - 第19回広仁会基礎医学研究賞
2015/06 - 平成27年度日本リウマチ財団海外派遣研修医

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