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J-GLOBAL ID：201801016736049955 Update date: Jan. 14, 2025

Nakamura Akiyoshi

Affiliation and department：

Research field (4)： Plants: molecular biology and physiology , Biophysics , Molecular biology , Structural biochemistry

Research keywords (6)：ゲノム編集 , 構造生物学 , X線結晶構造解析 , タンパク質科学 , 翻訳 , RNA

Research theme for competitive and other funds (7)：

2023 - 2026 The regulatory mechanism of gene expression via tRNA fragments generated by 3'-5' polymerase
2019 - 2023 Molecular basis of 3'-5' polymerase in a diverse RNA recognition
2016 - 2019 Study on a switching mechanism in RNA recognition by 3'-5' RNA polymerase
2012 - 2015 Elucidation of the molecular mechanism of the enzyme Thg1 which catalyzes template-dependent RNA chain elongation in the 3'- 5'direction
2011 - 2013 ピロリ菌由来アミノアシルtRNA 間接合成経路の分子機構

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Papers (38)：

Takuya Usui, Sayaka Ono, Akiyoshi Nakamura, Koji Kato, Toyoyuki Ose, Min Yao. Crystallographic analysis of the Escherichia coli tRNA seleno-modification enzyme in complex with tRNA. Acta Crystallographica Section F Structural Biology Communications. 2025. 81. 2
Akiyoshi Nakamura, Hiroshi Yamamoto, Tsubasa Yano, Reika Hasegawa, Yoichi Makino, Nobutaka Mitsuda, Teruhiko Terakawa, Seiichiro Ito, Shigeo S Sugano. Expanding the Genome-Editing Toolbox with Abyssicoccus albus Cas9 Using a Unique Protospacer Adjacent Motif Sequence. The CRISPR journal. 2024. 7. 4. 197-209
Akiyoshi Nakamura, Tsubasa Yano, Nobutaka Mitsuda, Maiko Furubayashi, Seiichiro Ito, Shigeo S Sugano, Teruhiko Terakawa. The sonication-assisted whisker method enables CRISPR-Cas9 ribonucleoprotein delivery to induce genome editing in rice. Scientific reports. 2023. 13. 1. 14205-14205
Maasa Yokomori, Hayato Suzuki, Akiyoshi Nakamura, Shigeo S. Sugano, Miho Tagawa. DNA-functionalized colloidal crystals for macromolecular encapsulation. Soft Matter. 2022. 18. 36. 6954-6964
Kentaro Ezura, Akiyoshi Nakamura, Nobutaka Mitsuda. Genome-wide characterization of the TALE homeodomain family and the KNOX-BLH interaction network in tomato. Plant molecular biology. 2022. 109. 6. 799-821

MISC (39)：

碓井拓哉, 大江花, 中村彰良, 尾瀬農之, 尾瀬農之, YAO Min, YAO Min. Structure determination of protein-tRNA complex using AlphaFold2 predicted model. Photon Factory News. 2022. 40. 3
中村彰良. Nucleotide recognition mechanism of human tRNA^His guanylyltransferase. 量子ビームサイエンスフェスタ(Web). 2021. 2020
中村彰良. Human tRNA^Hisguanylyltransferaseのヌクレオチド認識機構の解明. 日本結晶学会年会講演要旨集. 2021. 2021
中村彰良, WANG Daole, 小松康雄, 小松康雄. Analysis of nucleotide addition in the 3’-5’ direction by human tRNAHis guanylyltransferase and its application to RNA 5’-modification. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
中村彰良, 汪道楽, 小松康雄. ヒト由来tRNA^His guanylsltransferaseの塩基認識機構およびRNA5’修飾への応用. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd

Education (3)：

- 2010 Hokkaido University Graduate School of Life Science Division of Life Sciences
- 2006 北海道大学大学院理学研究科生物科学専攻 (修士)
- 2004 Hokkaido University School of Science

Work history (6)：

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Awards (3)：

2008/09 - Best Poster Presentation Award in International Conference on Aminoacyl-tRNA synthetases (aaRS2008)
2006/11 - 北海道大学国際交流基金Travel award
2006/11 - 北海道大学クラーク財団Travel award

Association Membership(s) (5)：

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE RNA SOCIETY OF JAPAN , 日本植物バイオテクノロジー学会 , 日本結晶学会

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