Rchr
J-GLOBAL ID:201801016905290055
Update date: Apr. 04, 2025 Hirata Eishu
ヒラタ エイシュウ | Hirata Eishu
Affiliation and department: Job title:
Associate Professor
Homepage URL (1): https://www.tcbb-kucri.org/ Research field (3):
Tumor biology
, Neurosurgery
, Neurology
Research keywords (15):
Brain tumor
, metastatic brain tumor
, Malignant glioma
, Tumor microenvironment
, Astrocyte
, Microglia
, Cancer Metastasis
, Drug Resistance
, Bioimaging
, FRET imaging
, Neurosurgery
, Neurology
, Migraine
, Migraine microenvironment
, Satellite glia
Research theme for competitive and other funds (13): - 2024 - 2032 Induction of cancer cell death by microglia and exploration of its regulatory mechanisms
- 2024 - 2027 Elucidating the glial network that eliminates metastatic cancer cells in the brain for clinical application
- 2024 - 2027 難溶性ペプチド群から医薬品を発掘する溶媒「双性イオン液体」の開発
- 2024 - 2027 ミクログリア制御によるがん脳転移治療・予防戦略の開発
- 2023 - 2025 グリオーマ関連ミクログリア・マクロファージの機能制御
- 2022 - 2025 Development of treatment strategies for cancer brain metastasis targeting metabotropic glutamate receptors
- 2020 - 2023 がん脳転移微小環境分子基盤の統合的理解と治療への応用
- 2019 - 2022 Epigenetic analysis and drug development with cell-reprogramming technology in atypical teratoid/rhabdoid tumor
- 2019 - 2021 アストロサイトを標的としたがん脳転移根治療法の開発
- 2017 - 2020 Elucidation of the nature of treatment-resistant tumor microenvironment in the central nervous system
- 2016 - 2019 Epigenomic analysis with reprogramming technology in lower grade glioma
- 2016 - 2018 脳転移がん細胞の休眠維持・破綻機構の解明と新規治療法の開発
- 2017 - 2018 ネオアンチゲン搭載型がんナノワクチン療法の開発
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Papers (38): -
Yuya Matsuda, Takeru Ishizaki, Takuya Uto, Issei Onoda, Richard W Wong, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda. Dual-Functionalized Zwitterionic Polymers for Cell Cryopreservation. Langmuir : the ACS journal of surfaces and colloids. 2025. 41. 6. 3888-3894
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Kumiko Taniguchi, Kei Sugihara, Takashi Miura, Daisuke Hoshi, Susumu Kohno, Chiaki Takahashi, Eishu Hirata, Etsuko Kiyokawa. Cholesterol synthesis is essential for the growth of liver metastasis-prone colorectal cancer cells. Cancer science. 2024
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Giovanni Giangreco, Antonio Rullan, Yutaka Naito, Dhruva Biswas, Yun-Hsin Liu, Steven Hooper, Pablo Nenclares, Shreerang Bhide, Maggie Chon U Cheang, Probir Chakravarty, et al. Cancer cell - Fibroblast crosstalk via HB-EGF, EGFR, and MAPK signaling promotes the expression of macrophage chemo-attractants in squamous cell carcinoma. iScience. 2024. 27. 9. 110635-110635
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Ryo Mizutani, Eishu Hirata. Intracardiac Injection Mouse Model to Study Cancer Cell Dormancy in Brain Metastasis. Methods in molecular biology (Clifton, N.J.). 2024. 2811. 113-122
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Kojiro Ishibashi, Eishu Hirata. Multifaceted interactions between cancer cells and glial cells in brain metastasis. Cancer science. 2024
more... MISC (27): -
Kuroda Kosuke, Hirata Eishu. Zwitterionic Liquids as Novel Solvents and Cryoprotectants. Cryobiology and Cryotechnology. 2023. 69. 1. 7-12
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Kuroda Kosuke, Hirata Eishu. Novel solvents for life sciences. 2022. 94. 2. 298-301
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丹下 正一朗, 平野 朋美, 井戸川 雅史, 平田 英周, 井本 逸勢, 時野 隆至. 膵臓がんにおける新規予後予測遺伝子の機能解析. 日本癌学会総会記事. 2021. 80回. [J15-6]
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平田 英周. 中枢神経系における治療抵抗性腫瘍微小環境の本態解明-Elucidation of the nature of treatment-resistant tumor microenvironment in the central nervous system-2018年度研究奨励金受領報告. 東京生化学研究会助成研究報告集. 2019. 34. 251-255
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平田 英周. 脳転移がん細胞の休眠維持と破綻の機構解明. 上原記念生命科学財団研究報告集. 2017. 31. 5p
more... Patents (7): -
細胞死誘導剤、医薬組成物、及びがん細胞検出薬
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現在非公開(特願2022-098339の優先権主張出願)
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現在非公開
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現在非公開
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脳転移がん抑制剤又は治療剤
more... Books (4): - がん生物学イラストレイテッド(第2版)第9章 6. 脳腫瘍
羊土社 2019 ISBN:9784758120968
- BRAF阻害薬による悪性黒色腫微小環境のparadoxical activationの分子機構
がん分子標的治療 14巻1号 遺伝子解析に基づく新しい分子標的治療 2016
- がん細胞とがん関連線維芽細胞の相互作用
生体の科学 67巻2号 細胞の社会学-細胞間で繰り広げられる協調と競争 2016
- イギリスの脳血管障害急性期医療
脳血管障害の急性期マネジメント(監修・橋本信夫、編・清水宏明)文光堂 2014 ISBN:9784830624018
Education (2): - - 2010 Kyoto University Graduate School of Medicine
- - 2002 Kyoto University School of Medicine
Professional career (2): - M.D. (Kyoto University)
- Ph.D. (Kyoto University)
Work history (9): - 2024/08 - 現在 WPI Nano Life Science Institute, Kanazawa University Professor
- 2024/08 - 現在 Cancer Research Institute of Kanazawa University Division of Tumor Cell Biology and Bioimaging Professor
- 2018/09 - 2024/07 WPI Nano Life Science Institute, Kanazawa University Associate Professor
- 2018/09 - 2024/07 Cancer Research Institute of Kanazawa University Division of Tumor Cell Biology and Bioimaging Associate Professor
- 2015/08 - 2018/08 Kanazawa Medical University Senior Assistant Professor
- 2015/04 - 2015/08 The Francis Crick Institute Research Fellow
- 2011/09 - 2015/03 Cancer Research UK London Research Institute Research Fellow
- 2010/06 - 2011/08 Kyoto University Graduate School of Biostudies Assistant Professor
- 2010/04 - 2010/05 Kyoto University Graduate School of Biostudies Postdoctoral fellow
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