
	Chemical structure search How to Search	Import MOLfile format is only available (V3000 format is not available) Exact match Substructure search Superstructure search Substructure or superstructure search Similarity search

Rchr

J-GLOBAL ID：201801017059636616 Update date: Feb. 16, 2025

Aoyama Hiroshi

Research keywords (5)：認知症 , リン酸誘導体 , 抗ガン剤 , 抗ウイルス薬 , プロテアーゼ阻害剤

Research theme for competitive and other funds (3)：

2013 - 2016 Application of phosphate mimetics to development of biologically active compounds
2010 - 2014 Chemical control of protein dramatype
2007 - 2009 Biological response modification based on multi-template and dramatype approaches.

Papers (64)：

Takayuki Nagae, Yuya Fujita, Tatsuya Tsuchida, Takanari Kamo, Ryoka Seto, Masako Hamada, Hiroshi Aoyama, Ayana Sato-Tomita, Tomotsumi Fujisawa, Toshihiko Eki, et al. Green/red light-sensing mechanism in the chromatic acclimation photosensor. Science Advances. 2024. 10. 24
Babak Kaboudin, Hiroshi Aoyama, Akihiro Sugiyama, Yoko Endo-Takahashi, Yoichi Negishi. Organic Phase-Soluble Nanomagnetically Cationic Phospholipid: Synthesis, Characterization, and In Vitro Transfection Activity. ACS applied materials & interfaces. 2023. 15. 28. 33437-33443
Hiroshi Aoyama, Yusuke Iizuka, Ryouta Kawanishi, Kazutaka Shibatomi, Yuki Arakawa, Hideto Tsuji, Yuu Hirose, Masaki Mishima. Efficient synthesis of γ-oxo carboxylic esters and isotope-labeled 5-aminolevulinic acid (5-ALA) by Pd(OAc)2/phosphonium tetrafluoroborates catalyzed Fukuyama coupling reaction. Tetrahedron Letters. 2023. 123
Ryo Kumagai, Ryohei Ono, Shu Sakimoto, Chiharu Suzuki, Ken-ichiro Kanno, Hiroshi Aoyama, Junko Usukura, Masataka Kobayashi, Hidefumi Akiyama, Hideyuki Itabashi, et al. Photo-cleaving and photo-bleaching quantum yields of coumarin-caged luciferin. Journal of Photochemistry and Photobiology A: Chemistry. 2023. 434. 114230-114230
山元智史, 森屋亮平, 中山淳, 伊集院良祐, 青山洋史, 山本雄介. FLT3陽性多発性骨髄腫を標的とした新規抗がん剤の合成と探索(Screening of novel anti-cancer drugs targeting FLT3-positive multiple myeloma cells). International Journal of Myeloma. 2022. 12. 3. 146-146

ｍore...

MISC (5)：

飯塚佑介, 永江峰幸, 青山洋史, 伊集院良祐, 伊藤隆, 広瀬侑, 三島正規. シアノバクテリアの光センサーのX線結晶構造解析と,NMRによるプロトン化状態の解析. 日本蛋白質科学会年会(Web). 2022. 22nd
Masanori Baba, Mohammed Salim, Mika Okamoto, Hiroshi Aoyama, Yuichi Hashimoto, Yutaka Takebe, Jan Paeshuyse, Johan Neyts. gamma-Carboline Derivatives as Potent and Selective Inhibitors of Bovine Viral Diarrhea Virus (BVDV) Replication. ANTIVIRAL RESEARCH. 2010. 86. 1. A29-A29
Aoyama Atsushi, Aoyama Hiroshi, Dodo Kosuke, Ishimoto Kenji, Makishima Makoto, Doi Takefumi, Hashimoto Yuichi, Miyachi Hiroyuki. Design, Synthesis and Evaluation of Novel Liver X Receptor (LXR) Antagonists Based on Conformational Restriction. Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2008. 34. 161-161
T Ikemoto, T Hosoya, T Hiramatsu, M Nakanishi, A Hosoya, H Aoyama, T Iwata, K Maruyama, M Suzuki, M Endo. Photoaffinity labeling of HMG-CoA reductase with azido-functionalized cerivastatin derivatives. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2004. 94. 139P-139P
Y Kihara, T Ikemoto, T Hosoya, H Aoyama, K Maruyama, M Suzuki, M Endo. Effects of dantrolene and its derivatives on Ca2+ release from the sarcoplasmic reticulum of skeletal muscle fibers. JAPANESE JOURNAL OF PHARMACOLOGY. 2002. 88. 217P-217P

Patents (4)：

ジフェニルメタン誘導体を有効成分とする抗ウイルス剤
新規ヒドロキサム酸誘導体
複素芳香族化合物を有効成分とする抗ウイルス剤
光学活性化合物の製造方法、及びその触媒

Lectures and oral presentations (3)：

Selective Acetylcholinesterase Inhibitors derived from Muscle Relaxant Dantrolene
(2019)
生物活性物質の探索とその効率に関連する金属触媒
(第18回関西大学先端科学技術シンポジウム 2014)
Pd触媒を用いた加アルコール分解による軸不斉ビフェノール類の速度論的光学分割
(若手研究者のための有機化学札幌セミナー 2005)

Education (3)：

2000 - 2003 Gifu University Graduate School of Engineering
1998 - 2000 Gifu University Graduate School of Engineering
1993 - 1997 Gifu University Faculty of Engineering Department of Chemistry

Work history (5)：

2013/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Pharmacy Associate Professor
2011/04 - 2013/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy Lecture
2006/08 - 2011/03 The University of Tokyo Institute of Molecular and Cellular Biosciences Assistant Professor
2006/01 - 2006/07 RIKEN Researcher
2003/04 - 2005/12 Japan Science and Technology Agency Solution-Oriented Research for Science and Technology Researcher

Association Membership(s) (1)：

日本化学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page


	Free word	※Add the following synonyms, you can increase the number of hits.




		～