Rchr
J-GLOBAL ID:201801017219399330
Update date: Feb. 19, 2025 Yokoyama Seiya
Yokoyama Seiya
Affiliation and department: Job title:
助教
Research field (2):
Experimental pathology
, Tumor diagnostics and therapeutics
Research keywords (5):
Machine learning
, Prognosis prediction
, Early Diagnosis
, DNA methylation
, Epigenetics
Research theme for competitive and other funds (21): - 2024 - 2027 ノンコーディングRNAを転写するMALAT1遺伝子のコーディングしない新規機能の解析
- 2024 - 2027 機械学習を用いた胆管癌悪性度予測モデルの構築
- 2023 - 2026 膠芽腫におけるドライバー遺伝子変異の空間的プロテオミクスへの基盤構築
- 2023 - 2026 膠芽腫におけるEGFR意義不明変異の機能解析
- 2022 - 2025 PDGFRA遺伝子変異の抗がん剤感受性マップの作製
- 2021 - 2024 膵胆管系腫瘍の早期診断と治療の為のバイオマーカー探索
- 2021 - 2024 Construction of DNA Methylation Markers for liqid biopsy of Pancreatic Cancer.
- 2019 - 2023 うがい液試料の統合的マルチオミクス解析に基づく口腔癌プレシジョン治療の実現
- 2021 - 膵癌摘出術後リスク判別法における適応可能な検体スペクトルの検討
- 2018 - 2021 Establishment of early diagnosis and treatment effect prediction method for pancreatobiliary neoplasm
- 2018 - 2021 Basic research for the development of novel aromatase inhibitors against breast cancer
- 2018 - 2021 A fundamental study for construction of bile duct cancer early diagnosis method by DNA methylation analysis.
- 2015 - 2018 Noninvasive detection of oral cancer and precancerous lesion using aberrant DNA methylation in gargle fluid samples
- 2015 - 2018 Attempt to establishment of early diagnosis and prediction of therapeutic response in pancreatobiliary neoplasms
- 2015 - 2018 A fundamental study for construction of PDAC early diagnosis method by DNA methylation analysis.
- 2014 - 2017 膵液を用いた新規メチル化解析法による膵癌の早期診断予測法の構築
- 2012 - 2015 Establishment of early diagnosis of pabcreatobiliary neoplasm
- 2012 - 2014 Basic research for early diagnosis of lung carcinomas by the application of DNA methylation analysis
- 2011 - 2014 Establishment of early diagnosis system of pancreatobiliary carcinomas by the application of mucin expression profiles
- 2012 - ムチン発現解析を応用した胆管癌の早期診断法の開発
- 2009 - 2011 Investigation of prognostic factor in pancreatobiliary neoplasm
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Papers (57): -
Saeki Saito, Hirofumi Yoshino, Seiya Yokoyama, Mitsuhiko Tominaga, Gang Li, Junya Arima, Ichiro Kawahara, Ikumi Fukuda, Akihiko Mitsuke, Takashi Sakaguchi, et al. Targeting Heat Shock Transcription Factor 4 Enhances the Efficacy of Cabozantinib and Immune Checkpoint Inhibitors in Renal Cell Carcinoma. International Journal of Molecular Sciences. 2025
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Taiji Hamada, Seiya Yokoyama, Toshiaki Akahane, Kei Matsuo, Ikumi Kitazono, Tatsuhiko Furukawa, Akihide Tanimoto. Electroporation Induces Unexpected Alterations in Gene Expression: A Tip for Selection of Optimal Transfection Method. Current Issues in Molecular Biology. 2025
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Mari Kirishima, Seiya Yokoyama, Toshiaki Akahane, Nayuta Higa, Hiroyuki Uchida, Hajime Yonezawa, Kei Matsuo, Junkoh Yamamoto, Koji Yoshimoto, Ryosuke Hanaya, et al. Prognosis prediction via histological evaluation of cellular heterogeneity in glioblastoma. Scientific reports. 2024. 14. 1. 24955-24955
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Nayuta Higa, Toshiaki Akahane, Mari Kirishima, Hajime Yonezawa, Ryutaro Makino, Hiroyuki Uchida, Seiya Yokoyama, Tomoko Takajo, Ryosuke Otsuji, Yutaka Fujioka, et al. All-in-one bimodal DNA and RNA next-generation sequencing panel for integrative diagnosis of glioma. Pathology, research and practice. 2024. 263. 155598-155598
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Takuya Yoshimura, Yuka Hirano, Taiji Hamada, Seiya Yokoyama, Hajime Suzuki, Hirotaka Takayama, Hirono Migita, Takayuki Ishida, Yasunori Nakamura, Masahiro Ohsawa, et al. Exercise Suppresses Head and Neck Squamous Cell Carcinoma Growth via Oncostatin M. Cancers. 2024
more... MISC (1): -
横山 勢也. 最も難治性である膵癌の早期質的診断ならびに進展度診断のシステム構築. 日本膵臓病研究財団研究報告書. 2012. 19回. 75-79
Patents (7): -
癌の判定装置、癌の情報取得方法及びプログラム
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予後推定装置、情報取得方法、プログラム及び胆道癌の予後推定用キット
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DISCRIMINATION METHOD OF PROGNOSTIC RISK AFTER PANCREATIC TUMOR EXTRACTION OPERATION
- 膵腫瘍の病型診断方法
- 新規なDNAメチル化解析方法
more... Books (18): - Methylation-Specific Electrophoresis
Springer US 2024 ISBN:9781071636695
- 【あの議論の決着はつきましたか?】病理・放射線関連 胆膵系腫瘍におけるムチン発現様式と悪性度は関係するのか?
医学図書出版(株) 2023 ISBN:9784865175233
- 【マイクロバイオームが切り拓く肝胆膵の新未来】胆道疾患 胆汁中細菌叢と膵胆道癌
(株)アークメディア 2023
- Gene Regulation and Therapeutics for Cancer. Edited By Surinder K. Batra, Moorthy Palanimuthu Ponnusamy
CRC Press 2020 ISBN:9780367541163
- 【IPMN大全】IPMNの歴史的変遷 IPMNにおけるMUC発現とその評価の歴史
医学図書出版(株) 2020
more... Lectures and oral presentations (55): -
血清miRNAによる口腔癌頸部リンパ節転移診断と後発転移予測法
(日本分子腫瘍マーカー研究会プログラム・講演抄録 2024)
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WHO新分類(WHO2021)の課題とその克服2:脳腫瘍病理形態診断と分子診断の融合の可能性 グリオーマに特化したカスタムDNA/RNAパネルを用いたクリニカルシーケンス
(Brain Tumor Pathology 2024)
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脳腫瘍1 小児脳腫瘍におけるカスタムDNA/RNAパネルを用いたクリニカルシーケンス
(小児の脳神経 2024)
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SNP解析に有効な飽和ゲノム編集(Saturation genome editing is effective for a study of single nucleotide polymorphism)
(日本病理学会会誌 2024)
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PDACにおける低酸素および低グルコース環境下でのMUC1の役割(The Role of MUC1 under Hypoxia and Low glucose condition in Pancreatic ductal adenocarcinoma)
(日本病理学会会誌 2024)
more... Professional career (1): Work history (4): - 2017/04 - 現在 Kagoshima University Department of Pathology, Graduate School of Medical and Dental Sciences Assistant Professor
- 2015/03 - 2017/03 University of Nebraska Medical Center Eppley Institute for Research in Cancer Postdoctoral Research Fellow
- 2012/04 - 2017/03 Kagoshima University Graduate School of Medical and Dental Sciences
- 2009/10 - 2012/03 Kagoshima University Graduate School of Medical and Dental Sciences
Awards (5): - 2022/02 - リバネス 鹿児島テックプランター・特別賞 革新的スクリーニング技術による膵臓癌の克服に向けて
- 2021/02 - A Grant from the Kodama Memorial Fund for Medical Research 優秀研究論文顕彰
- 2018/12 - 財団法人 膵臓病研究財団 膵臓病研究奨励賞
- 2012/10 - International Symposium on Pancreatic Cancer Young Investigator Award
- 2011/12 - 財団法人 膵臓病研究財団 膵臓病研究奨励賞
Association Membership(s) (2):
THE JAPANESE SOCIETY OF PATHOLOGY
, THE JAPANESE CANCER ASSOCIATION
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